|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Chronic myeloid leukemia-from the Philadelphia chromosome to specific target drugs:A literature review显示文摘Chronic myeloid leukemia(CML)is a myeloproliferative neoplasm and was the first neoplastic disease associated with a well-defined genotypic anomaly―the presence of the Philadelphia chromosome.The advances in cytogenetic and molecular assays are of great importance to the diagnosis,prognosis,treatment,and monitoring of CML.The discovery of the breakpoint cluster region(BCR)-Abelson murine leukemia(ABL)1 fusion oncogene has revolutionized the treatment of CML patients by allowing the development of targeted drugs that inhibit the tyrosine kinase activity of the BCR-ABL oncoprotein.Tyrosine kinase inhibitors(known as TKIs)are the standard therapy for CML and greatly increase the survival rates,despite adverse effects and the odds of residual disease after discontinuation of treatment.As therapeutic alternatives,the subsequent TKIs lead to faster and deeper molecular remissions;however,with the emergence of resistance to these drugs,immunotherapy appears as an alternative,which may have a cure potential in these patients.Against this background,this article aims at providing an overview on CML clinical management and a summary on the main targeted drugs available in that context. | Mariana Miranda Sampaio Maria Luísa Cordeiro Santos Hanna Santos Marques Vinícius Lima de Souza Gonçalves Glauber Rocha Lima Araújo Luana Weber Lopes Jonathan Santos Apolonio Camilo Santana Silva Luana Kauany de SáSantos Beatriz Rocha Cuzzuol Quézia Estéfani Silva Guimarães Mariana Novaes Santos Breno Bittencourt de Brito Filipe Antônio França da Silva Márcio Vasconcelos Oliveira Cláudio Lima Souza Fabrício Freire de Melo | 2021 | World Journal of Clinical Oncology2021，12，2： | 3 |
| 2 | Circulating lgE in patients with ordinary and crusted scabies 显示文摘 | Arlian LG Morgan MS Estes SA | 2004 | J Med Entomol2004，41，1： | 1 |
| 3 | Prevalence of sar- coptes scabiei in the homes and nursing homes of scabietic pa- tients显示文摘 | Arlian LG Estes SA Vyszenski - Moher DL | 1988 | J Am Aead Dermatol1988，19，5： | 1 |
| 4 | 7-Alkylcarbonyl anti 7-alkyloxycarbonyl prodrugs of theophylline显示文摘 | SLOAN KB DELLA VECCHIA SA ESTES JV | 2000 | Int J Pharm2000，205，12： | 1 |
| 5 | Circulating IgE inpatients with ordinary and crusted scabies 显示文摘 | Arlian LG Morgan MS Estes SA | 2004 | J Med Ento-mol2004，4，1： | 1 |
| 6 | Erysipeloid显示文摘 | Barnett JH Estes SA Wirman JA | 1983 | J Am Acad Dermatol1983，9，1： | 1 |
| 7 | 疥疮:另一侧面的研究显示文摘本文介绍了犬疥螨的生活周期;疥螨的生活方式、存活的必要条件、宿主的特异性,疥螨的免疫反应与室尘螨的交叉反应,可能引起的临床表现,以及疫苗预防疥疮的可能性等。疥疮能否传播HIV尚需进一步探讨。 | Estes SA 贾建琴 | 1994 | 国外医学(皮肤性病学分册)1994，20，4： | 1 |
| 8 | Circulating IgE in patients with ordinary and crusted scabies 显示文摘 | Arlian LG Morgan MS Estes SA | 2004 | J Med Entomol2004，，： | 1 |
| 9 | Staufen-and FMRP-containing neuronal RNPs are structurally and functionally related to somatic P bodies显示文摘 | Barbee SA Estes PS Cziko AM | 2006 | Neuron2006，52，6： | 1 |
| 10 | Staufen- and FMRP- containing neuronal RNPs are structurally and functionally re- lated to somatic P bodies 显示文摘 | Barbee SA Estes PS Cziko AM etal | 2006 | Neuron2006，52，6： | 1 |
| 11 | Staufen- and FMRP -containing neuronal RNPs are structurally and functionally related to somatic P bodies显示文摘 | Barbee SA Estes PS Cziko AM | 2006 | Neuron2006，52，6： | 1 |
| 12 | Should a patient's own IVF physician perform the embryo transfer?显示文摘 | Estes SJ Missmer SA Ginsburg ES | 2006 | J Assist Reprod Genet2006，23，5： | 1 |
| 13 | Diagnosis and management of scabies显示文摘 | Estes SA | | 0，，04： | 1 |
| 14 | Lipedematous alopecia显示文摘 | Bridges AG yon Kuster LC Estes SA | 2000 | Cutis2000，65，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员