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| 1 | Interventions to improve sarcopenia in cirrhosis: A systematic review显示文摘BACKGROUND Sarcopenia, i.e., muscle loss is now a well-recognized complication of cirrhosis and in cases of non-alcoholic fatty liver disease can contribute to accelerate liver fibrosis leading to cirrhosis. Hence, it is imperative to study interventions which targets to improve sarcopenia in cirrhosis.AIM To examine the relationship between interventions such nutritional supplementation, exercise, combined life style intervention, testosterone replacement and trans jugular intrahepatic portosystemic shunt(TIPS) to improve muscle mass in cirrhosis.METHODS We search PubMed, EMBASE and Cochrane between June-August 2018, without a limiting period and the types of articles(RCTs, clinical trial, comparative study)in adult patients with sarcopenia and cirrhosis. The primary outcome of interest was improvement in muscle mass, strength and physical function interventions mentioned above. In the screening process, 154 full text articles were included in the review and 129 studies were excluded.RESULTS We identified 24 studies that met review inclusion criteria. The studies were diverse in terms of the design, setting, interventions, and outcome measurements.We performed only qualitative synthesis of evidence due to heterogeneity amongst studies. Risk of bias was medium in most of the included studies and low quality of evidence showed improvement in the muscle mass, strength and physical function following aerobic exercise. 60% of the included studies on the nutritional intervention, 100% of the studies on testosterone replacement in hypogonadal men and trans-jugular portosystemic shunt were proved to be effective in improving sarcopenia in cirrhosis.CONCLUSION Although the quality of evidence is low, the findings of our systematic review suggest improvement in the sarcopenia in cirrhosis with exercise, nutritional interventions, hormonal and TIPS interventions. High quality randomized controlled trials needed to further strengthen these findings. | Maliha Naseer Erica P Turse Ali Syed Francis E Dailey Mallak Zatreh Veysel Tahan | 2019 | World Journal of Clinical Cases2019，7，2： | 8 |
| 2 | A high-density, multi-parental SNP genetic map on apple validates a new mapping approach for outcrossing species显示文摘Quantitative trait loci(QTL)mapping approaches rely on the correct ordering of molecular markers along the chromosomes,which can be obtained from genetic linkage maps or a reference genome sequence.For apple(Malus domestica Borkh),the genome sequence v1 and v2 could not meet this need;therefore,a novel approach was devised to develop a dense genetic linkage map,providing the most reliable marker-loci order for the highest possible number of markers.The approach was based on four strategies:(i)the use of multiple full-sib families,(ii)the reduction of missing information through the use of HaploBlocks and alternative calling procedures for single-nucleotide polymorphism(SNP)markers,(iii)the construction of a single backcross-type data set including all families,and(iv)a two-step map generation procedure based on the sequential inclusion of markers.The map comprises 15417 SNP markers,clustered in 3 K HaploBlock markers spanning 1267 cM,with an average distance between adjacent markers of 0.37 cM and a maximum distance of 3.29 cM.Moreover,chromosome 5 was oriented according to its homoeologous chromosome 10.This map was useful to improve the apple genome sequence,design the Axiom Apple 480 K SNP array and perform multifamily-based QTL studies.Its collinearity with the genome sequences v1 and v3 are reported.To our knowledge,this is the shortest published SNP map in apple,while including the largest number of markers,families and individuals.This result validates our methodology,proving its value for the construction of integrated linkage maps for any outbreeding species. | Erica A Di Pierro Luca Gianfranceschi Mario Di Guardo Herma JJ Koehorst-van Putten Johannes W Kruisselbrink Sara Longhi Michela Troggio Luca Bianco Hélène Muranty Giulia Pagliarani Stefano Tartarini Thomas Letschka Lidia Lozano Luis Larisa Garkava-Gustavsson Diego Micheletti Marco CAM Bink Roeland E Voorrips Ebrahimi Aziz Riccardo Velasco François Laurens W Eric van de Weg | 2016 | Horticulture Research2016，3，1： | 3 |
| 3 | ( + )-And (-)-borneol: efficacious positive modulators of GABAaction at human recombinant ell,82 2L GABAA receptors 显示文摘 | Renee E Granger Erica L Campbell Graham A R Johnston | 2005 | Bio- chem Pharmaco12005，69，： | 1 |
| 4 | Early iron deficiency alters sensorimotor development and brain monoamines in rats 显示文摘 | ERICA LU PAUL T LAURA E | 2007 | Nutr2007，137，： | 1 |
| 5 | Synthesis and characterization of xylan-coated magnetite microparticles 显示文摘 | Amanda K Andriola Silva Erica L da Silva Elquio E Oliveira | 2007 | lnternational Journal of Pharmaceutics2007，334，： | 1 |
| 6 | Duration of Lactation and Incidence of the Metabolic Syndrome in Women of Reproductive Age According to Gestational Diabetes Mellitus Status: A 20-Year Prospective Study in CARDIA (Coronary Artery Risk Development in Young Adults)显示文摘 | Gunderson Erica P Jacobs David R Chiang Vicky Lewis Cora E Feng Juanran Quesenberry Charles P Sidney Stephen | 2010 | Diabetes2010，，： | 1 |
| 7 | Unsupportive Responses from Others Concerning a Stressful Life Event:Development of the Unsupportive Social Interactions Inventory 显示文摘 | Kathleen M I Naney E B Erica J M | 2001 | Journal of Social and Clinical Psychology2001，20，： | 1 |
| 8 | Solubility of calcium sulfate salts in acidic manganese sulfate solutions from 30 to 105 ℃ 显示文摘 | Helen E Farrah Geoffrey A Lawrance Erica J Wanless | 2007 | Hydrometallurgy2007，86，： | 1 |
| 9 | Multiple laser treatments for macular edema attributable to branch retinal vein occlusion显示文摘 | Erica E Manju LS Jeffrey SH Anand KD Trexler MT Albert RF | 2005 | Am J Ophthalmol2005，139，： | 1 |
| 10 | Domestic Poultry and SARS Coronavirus Southern China 显示文摘 | Swayne David E Suarez David L Spackman Erica | 2004 | Emerging Infectious Diseases2004，10，5： | 1 |
| 11 | Ultra-high temperature ceramic coatings for oxidation protection of carbon-carbon compo-sites 显示文摘 | Erica L C Ronald E L | 2008 | J Eur Ceram Soc2008，91，5： | 1 |
| 12 | In vitro micropropagation of Primula scotic:a rare Scottish plant显示文摘 | Erica E | 2000 | Biodiversity and Conservation2000，9，： | 1 |
| 13 | Outcomes with retrievable inferior vena cava filters: a multicenter study显示文摘 | Charles E Erica M Zipser S | 2006 | J Vasc Interv Radiol2006，17，10： | 1 |
| 14 | Multiple laser treatments for macular edema attributable to branch retinal vein occlusion 显示文摘 | Erica E Manju L S Jeffrey SH etal | 2005 | Am J Ophthalmol2005，139，： | 1 |
| 15 | In vitro micropropagation of Primula scotic:a rare Scottish plant显示文摘 | Erica E Benson J E D anaher | 2000 | Biodiversity and Conservation2000，9，： | 1 |
| 16 | Cultural Factors in Social Anxiety: A Comparison of Social Phobia Symptoms aand Taijin Kyofusho显示文摘 | Dinnel D L Erica E H N | 1997 | Journal of Anxiety Disorders1997，11，2： | 1 |
| 17 | In vitro micropropagation of Primula scotic:a rare Scottish plant显示文摘 | Erica E Benson J anaher E D | 2000 | Biodiversity and Conservation2000，，9： | 1 |
| 18 | Outcomes with retrievable inferior vena cava filters:a muhicenter study显示文摘 | Charles E Erica M Zipser S | 2006 | J Vase Interv Radiol2006，17，10： | 1 |
| 19 | Unsupportive responses from others concerning a stressful life event:Development of the unsupportive social interactions inventory显示文摘 | Kathleen M I Nancy E B Erica J M | 2001 | Journal of Social and Clinical Psychology2001，20，2： | 1 |
| 20 | Identification of Phthalates in Medications and Dietary Supplement Formulations in the United States and Canada显示文摘 | Kelley Katherine E Hernández-Díaz Sonia Chaplin Erica L Hauser Russ Mitchell Allen A | 2012 | EN2012，，3： | 1 |
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