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| 1 | Deep-learning classifier with ultrawide-field fundus ophthalmoscopy for detecting branch retinal vein occlusion显示文摘AIM: To investigate and compare the efficacy of two machine-learning technologies with deep-learning(DL) and support vector machine(SVM) for the detection of branch retinal vein occlusion(BRVO) using ultrawide-field fundus images. METHODS: This study included 237 images from 236 patients with BRVO with a mean±standard deviation of age 66.3±10.6 y and 229 images from 176 non-BRVO healthy subjects with a mean age of 64.9±9.4 y. Training was conducted using a deep convolutional neural network using ultrawide-field fundus images to construct the DL model. The sensitivity, specificity, positive predictive value(PPV), negative predictive value(NPV) and area under the curve(AUC) were calculated to compare the diagnostic abilities of the DL and SVM models. RESULTS: For the DL model, the sensitivity, specificity, PPV, NPV and AUC for diagnosing BRVO was 94.0%(95%CI: 93.8%-98.8%), 97.0%(95%CI: 89.7%-96.4%), 96.5%(95%CI: 94.3%-98.7%), 93.2%(95%CI: 90.5%-96.0%) and 0.976(95%CI: 0.960-0.993), respectively. In contrast, for the SVM model, these values were 80.5%(95%CI: 77.8%-87.9%), 84.3%(95%CI: 75.8%-86.1%), 83.5%(95%CI: 78.4%-88.6%), 75.2%(95%CI: 72.1%-78.3%) and 0.857(95%CI: 0.811-0.903), respectively. The DL model outperformed the SVM model in all the aforementioned parameters(P<0.001). CONCLUSION: These results indicate that the combination of the DL model and ultrawide-field fundus ophthalmoscopy may distinguish between healthy and BRVO eyes with a high level of accuracy. The proposed combination may be used for automatically diagnosing BRVO in patients residing in remote areas lacking access to an ophthalmic medical center. | Daisuke Nagasato Hitoshi Tabuchi Hideharu Ohsugi Hiroki Masumoto Hiroki Enno Naofumi Ishitobi Tomoaki Sonobe Masahiro Kameoka Masanori Niki Yoshinori Mitamura | 2019 | International Journal of Ophthalmology(English edition)2019，12，1： | 16 |
| 2 | Detection of cytotoxin genotypes of Helicobacter pylori in stomach, saliva and dental plaque显示文摘 | Denise G. Silva Roy H. Stevens Jacyara M.B. Macedo Rodolpho M. Albano Marcio E.V. Falabella Enno C.I. Veerman Eduardo M.B. Tinoco | 2009 | Archives of Oral Biology2009，，7： | 3 |
| 3 | 应用无标定激光诱导击穿光谱法分析钢铁工业中氧化物材料显示文摘激光诱导击穿光谱技术是一种具有吸引力的快速定量表征材料的方法,可用于工业过程的在线监控。本文报告了该技术在多元氧化物材料分析上应用。采用激光诱导击穿光谱技术分析钢工业生产的炉渣和混合氧化物试料,然后以无标定法测定其中氧化物的浓度,结果发现,对于本研究所涉及的材料,无标定激光诱导击穿光谱方法的测定浓度值与参考值一致,大部分样品和氧化物组分的绝对误差小于2%(质量分数),大范围改变测定参数时浓度值保持稳定。研究结果表明激光诱导击穿光谱技术作为钢铁工业中新型的分析测试技术具有很大潜力。 | PEDARNIG Johannes D HEITZ Johannes PRAHER Bernhard KOLMHOFER Philipp HUBER Norbert RSSLER Roman WOLFMEIR Hermann ARENHOLZ Enno | 2012 | 冶金分析2012，32，8： | 2 |
| 4 | Remote electronic blood release system显示文摘 | Cox C Enno A Deveridge S | 1997 | Transfusion1997，37，9： | 1 |
| 5 | The four-electrode resistivity technique in anisotropic media:theoretical analysis and application on myocardi al tissue in vivo显示文摘 | Paul S Gerrit M Enno T | 1993 | IEEE Trans on Biomedical Engineering1993，40，： | 1 |
| 6 | Stresses developed in optical film coatings 显示文摘 | Ennos A E | 1996 | Appl Opt1996，5，1： | 1 |
| 7 | The fracture properties and mechanical designof human fingernails 显示文摘 | Fatten L Shayler S Ennos A R | 2004 | J Exp Biol2004，207，： | 1 |
| 8 | Herbivore specific induc-tion of silica-based plant defenses显示文摘 | Massey F P Ennos A R Hartley S E | | 0，，4： | 1 |
| 9 | Recording of inplane Surface Displacement by Double Exposure Speckle Photography显示文摘 | Archbold E Bureh J M Ennos A E | 1970 | Opt Acta1970，17，12： | 1 |
| 10 | Gastric mucosa-associated lymphoid tissue lymphoma: implications of animal models on pathogenic and ther-apeutic considerations-mouse models of gastric lymphoma 显示文摘 | LEE A O' ROURKE J ENNO A | 2000 | Recent Results Cancer Res2000，156，1： | 1 |
| 11 | Gasreic mucosa-associated lymphoid tissue lymphoma:implications of animal models on pathogenic and therapeutic considerations-mouse models of gastric lymphoma显示文摘 | O′Rourke J Enno A | 2000 | Recent Results Cancer Res2000，156，： | 1 |
| 12 | 'City form and natural process' - indicators for the ecological performance of urban areas and their application to Merseyside, UK 显示文摘 | Whitford V Ennos A R Handley J F | 2001 | Landscape and Urban Planning2001，57，2： | 1 |
| 13 | The aerodynamics and hydrodynamics of plants 显示文摘 | Ennos A R | 1999 | The Journal of Experimental Biology1999，202，： | 1 |
| 14 | Modelingthe environmental impacts of urban land use and land cover change-Astudy in Merseyside,UK显示文摘 | STEPHAN PAULEIT ROLAND ENNOS YVONNE GOLDING | 2005 | Landscape and Urban Planning2005，71，： | 1 |
| 15 | Characterising the urban environment of UK citise and towns:a template for landscape planning显示文摘 | GILL S E HANDLEY J F ENNOS A R | 2008 | Landscape and Urban Planning2008，87，3： | 1 |
| 16 | Wind as an ecological factor显示文摘 | Ennos A R | 1997 | Trends in Ecology and Evolution1997，12，： | 1 |
| 17 | Modeling the environmental impacts of urban land use and land cover change--a study in Merseyside, UK 显示文摘 | Pauleit S Ennos R Goldlng Y | 2005 | Landscape and Urban Planning2005，71，： | 1 |
| 18 | The genetic management of native species in Scotland显示文摘 | Ennos R A Worrell R Malcolm D C | 1998 | Forestry1998，71，1： | 1 |
| 19 | City form and natural process - Indicators for the ecological performance of urban areas and their application to Merseyside, UK显示文摘 | Whitford V A R Ennos | 2000 | Landscape and Urban Planning2000，，57： | 1 |
| 20 | The effects of soil bulk density on the morphology and anchorage mechanics of the root systems of sunflower and maize显示文摘 | Goodman A M Ennos A R | 1999 | Annals of Botany1999，83，3： | 1 |
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