|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Comparison of multinomial logistic regression and logistic regression: which is more efficient in allocating land use?显示文摘陆地使用变化的空间地明确的模拟是在精力流动,生态学和环境上估计陆地使用和盖子变化的效果的基础。在象素水平,逻辑回归是在分配建模决定在陆地使用之间的关系的空间地明确的陆地使用使用的最普通的途径之一,它在开车的原因的因素打使用变化,并且从而使用适用性评估土地。然而,这些模型有一个缺点因为他们不基于在陆地使用变化和它的开车因素之间的直接关系决定 / 分配陆地使用。因而,一个多项的逻辑回归方法被介绍探讨这个缺陷,并且从而,在江西省的一个案例研究区域在任何给定的象素判定陆地使用的一种类型的适用性,中国。二个回归方法的比较比用逻辑回归获得了的显示用多项的逻辑回归的正确地分配的象素的比例是 92.98% ,它高是 8.47% 。配对的 t 测试结果也证明象素被多项的逻辑回归更清楚地比由逻辑回归区分。在结论,多项的逻辑回归是为陆地使用变化的空间分配的一个更有效、精确的方法。在未来陆地使用变化研究的这个方法的申请可以改进在精力流动,生态学,和环境上预言陆地使用和盖子变化的效果的精确性。 | Yingzhi LIN Xiangzheng DENG Xing LI Enjun MA | 2014 | Frontiers of Earth Science2014，8，4： | 9 |
| 2 | The zinc transporter Slc39a5 controls glucose sensing and insulin secretion in pancreatic β-cells via Sirt1- and Pgc-1α-mediated regulation of Glut2显示文摘Zinc levels are high in pancreatic β-cells, and zinc is involved in the synthesis, processing and secretion of insulin in these cells. However, precisely how cellular zinc homeostasis is regulated in pancreatic β-cells is poorly understood. By screening the expression of 14 Slc39a metal importer family member genes, we found that the zinc transporter Slc39a5 is significantly downregulated in pancreatic β-cells in diabetic db/db mice, obese ob/ob mice and high-fat diet-fed mice. Moreover,β-cell-specific Slc39a5 knockout mice have impaired insulin secretion. In addition, Slc39a5-deficient pancreatic islets have reduced glucose tolerance accompanied by reduced expression of Pgc-1α and its downstream target gene Glut2. The down-regulation of Glut2 in Slc39a5-deficient islets was rescued using agonists of Sirt1, Pgc-1α and Ppar-γ. At the mechanistic level, we found that Slc39a5-mediated zinc influx induces Glut2 expression via Sirt1-mediated Pgc-1α activation. These findings suggest that Slc39a5 may serve as a possible therapeutic target for diabetes-related conditions. | Xinhui Wang Hong Gao Wenhui Wu Enjun Xie Yingying Yu Xuyan He Jin Li Wanru Zheng Xudong Wang Xizhi Cao Zhuoxian Meng Ligong Chen Junxia Min Fudi Wang | 2019 | Protein & Cell2019，10，6： | 6 |
| 3 | The structure of erastin-bound xCT-4F2hc complex reveals molecular mechanisms underlying erastin-induced ferroptosis显示文摘Dear Editor,Ferroptosis is an iron-dependent,non-apoptotic form of regulated cell death characterized by an accumulation of lipid.derived reactive oxygen species(ROS).The small-molecule compo und erastin in duces ferroptosis via in hibiti ng the cystineglutamate antiporter system x_(c).which consists of two subunits,namely the light chain xCT and the heavy chain 4F2hc(encoded by the SLC7A11 and SLC3A2 genes,respectively).^(1-4) | Renhong Yan Enjun Xie Yaning Li Jin Li Yuanyuan Zhang Ximin Chi Xueping Hu Lei xu Tingjun Hou Brent R.Stockwell Junxia Min Qiang Zhou Fudi Wang | 2022 | Cell Research2022，32，7： | 4 |
| 4 | Dissecting Abscisic Acid Signaling Pathways Involved in Cuticle Formation显示文摘表皮是在植物和环境之间的天线植物表面和一个重要相互作用点的外部物理障碍。许多环境压力影响表皮形成,然而,包含的规章的小径仍然保持未定义。我们在 Arabidopsis thaliana 使用了遗传和基因表达式分析定义表明断然经由表明小径的核心骆驼毛的织物调整表皮形成的循环的 abscisic 酸(骆驼毛的织物) ,包括 PYR/PYL 受体, PP2C 磷酸酶,和 SNF1 相关的蛋白质 Kinase (SnRK ) 2.2/SnRK2.3/SnRK2.6。SnRK2 kinases 下游,表皮形成没被骆驼毛的织物应答的元素绑定抄写因素,但是由相当调整使脱蜡, MYB16, MYB94,和 MYB96。另外,低空气湿度增加了核心骆驼毛的织物小径和表明表皮生合成基因的稀释表示的房间 death/reactive 氧种类的表皮形成独立人士。在 Physcomitrella 圣餐盘,外长的骆驼毛的织物压制了表皮相关的基因的表示, orthologs 是其 Arabidopsis 导致骆驼毛的织物。因此,调整表皮形成的机制被保存但是在陆地植物复杂。与表皮缺乏有关明确地发信号被识别在表明小径异种到增加的湿度并且在 modulating 的骆驼毛的织物的改编起一个主要作用他们的免疫到在 Arabidopsis 的 Botrytis cinerea。这些结果在表明调整回答到外部环境的小径的 ABA 定义一个表皮特定的下游的分支。 | Fuqiang Cui Mikael Brosche Mikko T. Lehtonen Ali Amiryousefi Enjun Xu Matleena Punkkinen Jari P.T. Valkonen Hiroaki Fujii Kirk Overmyer | 2016 | Molecular Plant2016，9，6： | 3 |
| 5 | Two Arabidopsis Receptor-like Cytoplasmic Kinases SZE1 and SZE2 Associate with the ZAR1-ZED1 Complex and Are Required for Effector-Triggered Immunity显示文摘Plants utilize intracellular nucleotide-binding leucine-rich repeat domain-containing receptors (NLRs) to recognize pathogen effectors and induce a robust defense response named effector-triggered immunity (ETI). The Arabidopsis NLR protein HOPZ-ACTIVATED RESISTANCE 1 (ZAR1) forms a precomplex with HOPZ-ETI-DEFICIENT 1 (ZED1),a receptor-like cytoplasmic kinase (RLCK) XII-2 subfamily member, to recognize the Pseudomonas syringae effector HopZ1 a. We previously described a dominant mutant of Arabi-dopsis ZED1, zed1-D, which displays temperature-sensitive autoimmunity in a ZAR1-dependent manner. Here, we report that the RLCKs SUPPRESSOR OF ZED1-D1 (SZE1) and SZE2 associate with the ZAR1-ZED1 complex and are required for the ZED7-D-activated autoimmune response and HopZ1a-triggered immunity. We show that SZE1 but not SZE2 has autophosphorylation activity, and that the N-terminal myristoylation of both SZE1 and SZE2 is critical for their plasma membrane localization and ZED1-D-activated autoimmunity. Furthermore, we demonstrate that SZE1 and SZE2 both interact with ZAR1 to form ja functional complex and are required for resistance against P. syringae pv. tomato DC3000 ex-pressing HopZIa. We also provide evidence that SZE1 and SZE2 interact with HopZ1a and function together with ZED1 to change the intramolecular interactions of ZAR1, leading to its activation. Taken together, our re-sults reveal SZE1 and SZE2 as critical signaling components of HopZ1a-triggered immunity. | Cheng Liu Dayong Cui Jingbo Zhao Na Liu Bo Wang Jing Liu Enjun Xu Zhubing Hu Dongtao Ren Dingzhong Tang Yuxin Hu | 2019 | Molecular Plant2019，12，7： | 1 |
| 6 | Xors in the air:practical wireless net- work coding 显示文摘 | Sachin Katti Hafiharan Rahul W enjun Hu Dina Katabi Muriel Medard Jon Crowcroft | 2008 | mEE/ACM Transactions on Networking2008，16，3： | 1 |
| 7 | Syn- thesis, Characterization, Interaction with DNA and Cytotoxicity in Vitro of Dinuclear Pd(lI) and Pt(ll) Complexes Dibridged by 2, 2'-Azanediyldibenzoic Acid 显示文摘 | Gao Enjun Zhu Mingchang Yin Hongxi | 2008 | JOUl''llal of Inorganic Biochemistry2008，102，10： | 1 |
| 8 | Hot-carrier and Soft-break- down Effects on VCO Performance显示文摘 | ENJUN X YUAN J S HONG Y | 2002 | IEEE Transactions on Microwave Theory and Techniques2002，50，11： | 1 |
| 9 | Preliminary Study on Anther in vitro Culture of Lily“Prato”显示文摘The effects of the microspore developmental stage,hormones and culture condition on anther in vitro culture of lily(Lilium spp.) were discussed.The results showed that when the flower buds were about 23-26 mm long,the microspores were at the uninucleate stage which was suitable for culture and the culture under the darkness would promote the callus induction of anther.The induction frequency could reach 42.5% in the optimized medium which was MS+[6-BA(0.5)+KT(2.0)+2,4-D(1.0)] mg·L-1.The rate of callus differentiation could reach 31.57% in the optimized medium which was MS+ NAA(1.5,2.0) mg·L-1. | FAN Jinping PING Zhongyuan XU Enjun PAN Bingbing CHE Daidi | 2011 | Journal of Northeast Agricultural University(English Edition)2011，18，1： | 1 |
| 10 | Doping mode,band structure and photocatalytic mechanism of B-N-codoped TiO2显示文摘 | Yuan Jixiang Wang Enjun Chen Yongmei | 2011 | Applied Surface Science2011，257，16： | 1 |
| 11 | Rewiring ERBB3 and ERK signaling confers resistance to FGFR1 inhibition in gastrointestinal cancer harbored an ERBB3-E928G mutation显示文摘Dear Editor,Recently,a large number of studies found that activation of ERBB3(Erb-B2 receptor tyrosine kinase 3,also known as HER3)may be one of the major mechanisms underlying resistance to therapies that target the EGFR(epidermal growth factor receptor),HER2,and other receptor tyrosine kinases(RTKs)(Chen et al.,2011;Choi et al.,2012;Ross et al.,2018).Interestingly,mutations in ERBB3 are commonly reported in gastrointestinal(Gl)cancer,with mutations identified in approximately 12%of stomach and colorectal cancer cases(Jaiswal et al.,2013). | Xiang Yang Hongxiao Wang Enjun Xie Biyao Tang Qingdian Mu Zijun Song Junyi Chen Fudi Wang Junxia Min | 2020 | Protein & Cell2020，11，12： | 1 |
| 12 | Biodieselproduction via transesterification of soybean oil using acidcatalyst in CO2expanded methanol liquids显示文摘 | MA Zhen SHANG Ziyang WANG Enjun | 2012 | Industrial &engineering chemistry research2012，51，12： | 1 |
| 13 | Study on Chemical Grout Permeation Mechanism Based on Experiment of Mud and Sand Medium显示文摘 | Duo Tian Haoyu Shi Enjun Fu | 2012 | PRSE2012，，10： | 1 |
| 14 | Research on the Production Process of Apple Cl ear Juice Beverage显示文摘 | ZHU Xia HAN Shunyu YANG Xueshan WANG Jin SHENG W enjun ZHANG Bo | | 0，，04： | 1 |
| 15 | Impacts of Vegetation Change on the Regional Surface Climate: A Scenario-Based Analysis of Afforestation in Jiangxi Province, China显示文摘 | Enjun Ma Anping Liu Xing Li Feng Wu Jinyan Zhan Xiangzheng Deng | 2013 | Advances in Meteorology2013，，： | 1 |
| 16 | Research on the Networ Organization and theOrganizational Capacity of Disruptive Technology Innovation 显示文摘 | Shengjan Sun Enjun Xia | 2005 | Proceed-ings of 2005 International Conference on Management Science and Engi-neering2005，，： | 1 |
| 17 | A study on the dependence of the micro-pore configurations on the volatilization and the burn processes of the organic compounds in the matrix of molten carbonate fuel cells显示文摘 | Lin Huaxin Zhou Li He Changqing Kong Lianying Zhang Enjun Yi Baolian | 2002 | Electrochimica Acta2002，，9： | 1 |
| 18 | Tintinnid community throughout the Bohai Sea during the spring显示文摘As one of the important microzooplankton in marine pelagic habitats,tintinnids are classified as neritic genera,oceanic genera and cosmopolitan genera.Until now,we know little about the interaction between neritic and oceanic genera in continental shelves.Low species richness area was found in the mixing area between neritic and oceanic genera in the East China Sea.In this study,we investigated the spatial distribution of tintinnid community throughout the entire Bohai Sea in May(spring)of 2014 to find out:(1)whether the tintinnid assembalges differed in the three major bays bordering this shallow inland sea;(2)whether there was low species richness area in the Bohai Sea.Three genera and 11 species attributed to neritic and cosmopolitan taxa were reported from this region.Tintinnid abundance averaged(81±216)ind./L(0–1234 ind./L).Tintinnid community differed within the three major bays,with each characterized by different tintinnid taxa.Referring to the average abundance of three bays,tintinnids were most abundant in the Laizhou Bay((328±445)ind./L),and least abundant in the Liaodong Bay((34±57)ind./L).A low species richness area occurred in the central Bohai Sea(20–40 m isobaths),in some stations of which no tintinnid was recorded.Our study demonstrates that tintinnid community varied greatly over small spatial scales,and low species richness area was found in the mixing area between neritic and oceanic genera within this inland sea. | Ying Yu Feng Zhou Wuchang Zhang Chen Wei Qunshan Wang Enjun Fang | 2020 | Acta Oceanologica Sinica2020，39，6： | 0 |
| 19 | Economical Analysis on the Causes and Effects of the "Shell" Resource of the Professional Football Clubs in China显示文摘 | Sha Ge Enjun Wu Yue Wang | 2006 | Chinese Business Review2006，5，7： | 0 |
| 20 | Targeting the LSD1-G9a-ER Stress Pathway as a Novel Therapeutic Strategy for Esophageal Squamous Cell Carcinoma显示文摘Despite recent advances in the management and treatment of esophageal squamous cell carcinoma(ESCC),the prognosis remains extremely poor,and current nonsurgical treatment options are limited.To identify new therapeutic targets,we screened a curated library of epigenetic compounds using a panel of cancer cell lines and found that coinhibiting the histone demethylase LSD1 and the histone methyltransferase G9a potently suppresses cell growth;similar results were obtained by knocking down both LSD1 and G9a expression.Importantly,we also found that inhibiting LSD1 and G9a significantly decreased tumor growth in a xenograft mouse model with ESCC cell lines.To examine the clinical relevance of these findings,we performed immunohistochemical analyses of microarray profiling data obtained from human esophageal squamous cancer tissues and found that both LSD1 and G9a are upregulated in cancer tissues compared to healthy tissues,and this increased expression was significantly correlated with poor prognosis.Mechanistically,we discovered that inhibiting LSD1 and G9a induces cell death via S-phase arrest and apoptosis,and cotargeting ER stress pathways increased this effect both in vitro and in vivo.Taken together,these findings provide compelling evidence that targeting LSD1,G9a,and ER stress-related pathways may serve as a viable therapeutic strategy for ESCC. | Hongxiao Wang Zijun Song Enjun Xie Junyi Chen Biyao Tang Fudi Wang Junxia Min | 2022 | Research2022，，3： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员