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| 1 | Fondaparinux预防老年急性内科患者发生静脉血栓形成的效果与安全性:随机安慰剂对照研究显示文摘目的:观察 Fondaparinux 对具有中高度静脉血栓发生危险的老年急性内科住院患者的抗凝效果与安全性。设计:双盲随机安慰剂对照研究。背景:8个国家的35个中心。参与者:849例≥60岁内科患者,住院原因分别为充血性心力衰竭、慢性肺病合并急性呼吸系统疾患、急性炎症性或感染性疾病,预期至少住院4天以上。干预:2.5 mg Fondaparinux 或安慰剂,每天1次皮下注射,持续6~14天。观察指标:主要指标为静脉血栓形成(治疗后15天内采用双侧静脉造影检查)及有症状的静脉血栓;次要指标为死亡与出血。患者随访时间为1个月。结果:Fondaparinux 治疗组425例患者和安慰剂组414例患者接受了安全性分析(10例未治疗)。644例患者(75.9%)可接受主要指标分析。静脉血栓检出率在 Fondaparinux 治疗组为5.6%(18/321),安慰剂组为10.5%(34/323),相对危险减少46.7%(95% CI 7.7%~69.3%)。安慰剂组5例患者发生有症状的静脉血栓,Fondaparinux治疗组无患者发生有症状的静脉血栓(P=0.029)。两组均有1例(0.2%)患者发生严重出血。随访结束时,安慰剂组、Fondaparinux 治疗组分别死亡25(6.0%)、14(3.3%)例患者。结论:Fondaparinux 可有效预防急性内科老年患者无症状性及有症状的静脉血栓。严重出血几率两组相似。 | Alexander T Cohen Bruce L Davidson Alexander S Gallus Michael R Lassen Martin H Prins Witold Tomkowski Alexander G G Turpie Jan F M Egberts Anthonie W A Lensing 石汉平(译) 王深明(校) | 2006 | 英国医学杂志中文版2006，9，5： | 3 |
| 2 | Analysis of Time-se- ries MODIS 250 m Vegetation Index Data for Crop Classifica- tion in the US Central Great Plains显示文摘 | Wardlow B D Egbert S L Kastens J H | 2007 | Remote Sensing of Environment2007，108，6： | 1 |
| 3 | Large-area Crop Mapping Using Time-series MODIS 250 m NDVI Data: An Assessment for the US Central Great Plains显示文摘 | Wardlow B D Egbert S L | 2008 | Remote Sensing of Environ- ment2008，112，3： | 1 |
| 4 | 查看详情显示文摘 | Wardlow B D Egbert S L | | 0，，： | 1 |
| 5 | An investigation of power line de-icing by electro-impulse methods显示文摘 | EGBERT R I SCHRAG R L BERNHART W D | 1989 | IEEE Transactions on Power Delivery1989，4，3： | 1 |
| 6 | An investigation of power line de-icing by electro-impulse methods显示文摘 | Egbert R I Schrag R L Bernhart W D | 1989 | IEEE Trans on Power Delivery1989，4，3： | 1 |
| 7 | An investigation of line deicing by electro impulse methods 显示文摘 | EGBERT R I SCHRAG R L BERNHART W D | 1989 | IEEE Transactions on Power Delivery1989，4，3： | 1 |
| 8 | Clinical and pharmacogenetic determinants for the discontinuation of non-ergoline dopamine agonists in Parkinsons disease显示文摘 | ARBOU W M E L MOVIG K L L EGBERTS T C G POELS P J E VAN VUGT J P P WESSELS J A M VAN DER STRAATEN R J H M NEEF C GUCHELAAR H J | 2009 | Eur J Clin Pharm2009，65，12： | 1 |
| 9 | Diode laser transscleral cyclophotocoagulation as a primary surgical treatment for primary open-angle glaucoma显示文摘 | Egbert P R Fiadoyor S Budenz D L | 2001 | Arch ophthalmo2001，119，1： | 1 |
| 10 | Analysis of time-series MODIS 250 m vegetation index data for crop classification in the U S Central Great Plains显示文摘 | Wardlow B D Egbert S L Kastens J H | 2007 | Remote Sensing of Environment2007，108，： | 1 |
| 11 | High specifici-ty of myositis specific autoantibodies for myositis compared with oth-er neuromuscular disorders显示文摘 | Hengstman GJ van Brenk L Vree Egberts WT | 2005 | J Neurol2005，252，5： | 1 |
| 12 | Conflicz, strese and adap- tation, New Engl显示文摘 | Egbert L Malins Af Melzack R | 2008 | Med2008，，： | 1 |
| 13 | Conflict, stress and adaptation 显示文摘 | Egbert L Malins A F Melzack R | 1964 | New Engl J Med1964，，： | 1 |
| 14 | A comparison of MODIS 250-m EVI and NDVI data for crop mapping:a case study for southwest Kansas显示文摘 | Wardlow B D Egbert S L | 2010 | International Journal of Remote Sensing2010，31，3： | 1 |
| 15 | Correlation between probe shape and a- tomic friction peaks at graphite step edges显示文摘 | Dong Y L Liu X Z Egberts P Ye Z J Carpick R W Martini A | 2012 | Tribol- ogy Letters2012，50，1： | 1 |
| 16 | An investigation of power line deicing by electro-impulse methods显示文摘 | EGBERT R I SCHRAG R L BERNHART W D | 1989 | IEEE Transactions on Power Delivery1989，4，3： | 1 |
| 17 | An investigation of power line de-icing by electro-impulse methods显示文摘 | Egbert R I Schrag R L Bernhart W D | 1989 | IEEE Trans on Power Delivery1989，4，3： | 1 |
| 18 | Pedagogy,process,and classroom context:Integrating teacher voice and experience into research on technology-enhanced language learning显示文摘 | Egbert J Huff L Mc Neil L | 2009 | The Modern Language Journal2009，93，1： | 1 |
| 19 | Reduction of postoperative pain by encouragement and instruction of patients a study of doctor-patient rapport显示文摘 | Egbert L D Battit G E Welch C E | 1964 | N Engl J Med1964，270，16： | 1 |
| 20 | Large-area Crop Mapping Using Time-series MODIS 250 m NDVI Data:Anassessment for the US Central Great Plain显示文摘 | Wardlow B D Egbert S L | 2008 | Remote Sensing of Environment2008，112，： | 1 |
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