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| 1 | Adjuvant chemotherapy and acute toxicity in hypofractionated radiotherapy for early breast cancer显示文摘AIM: To evaluate the effect of chemotherapy to the acute toxicity of a hypofractionated radiotherapy(HFRT) schedule for breast cancer. METHODS: We retrospectively analyzed 116 breast cancer patients with T1, 2N0 Mx. The patients received3-D conformal radiotherapy with a total physical dose of 50.54 Gy or 53.2 Gy in 19 or 20 fractions according to stage, over 23-24 d. The last three to four fractions were delivered as a sequential tumor boost. All patients were monitored for acute skin toxicity according to the European Organization for Research and Treatment of Cancer/Radiation Therapy Oncology Group criteria. The maximum monitored value was taken as the final grading score. Multivariate analysis was performed for the contribution of age, chemotherapy and 19 vs 20 fractions to the radiation acute skin toxicity.RESULTS: The acute radiation induced skin toxicity was as following: grade Ⅰ 27.6%, grade Ⅱ 7.8% and grade Ⅲ 2.6%. No significant correlation was noted between toxicity grading and chemotherapy(P = 0.154, χ2 test). The mean values of acute toxicity score in terms of chemotherapy or not, were 0.64 and 0.46 respectively(P = 0.109, Mann Whitney test). No significant correlation was also noted between acute skin toxicity and radiotherapy fractions(P = 0.47, χ2test). According to univariate analysis, only chemotherapy contributed significantly to the development of acute skin toxicity but with a critical value of P = 0.05. However, in multivariate analysis, chemotherapy lost its statistical significance. None of the patients during the 2-years of follow-up presented any locoregional relapse.CONCLUSION: There is no clear evidence that chemotherapy has an impact to acute skin toxicity after an HFRT schedule. A randomized trial is needed for definite conclusions. | Vassilis Kouloulias Anna Zygogianni Efrosini Kypraiou John Georgakopoulos Zoi Thrapsanioti Ivelina Beli Eftychia Mosa Amanta Psyrri Christos Antypas Christina Armbilia Maria Tolia Kalliopi Platoni Christos Papadimitriou Nikolaos Arkadopoulos Costas Gennatas George Zografos George Kyrgias Maria Dilvoi George Patatoucas Nikolaos Kelekis John Kouvaris | 2014 | World Journal of Clinical Cases2014，2，11： | 1 |
| 2 | Investigating brain tumor dif{erentiation with diffusion and perfusion metrics at 3T MRI using pattern recognition techniques显示文摘 | Patricia S Evangelia T Eftychia K | 2013 | Magn Reson Imaging2013，31，9： | 1 |
| 3 | BR AF and RAS oncogenes regulate Rho GTPase pathways to mediate migration and invasion properties in human colon cancer cells:a comparative study显示文摘 | Eleni Makrodouli Eftychia Oikonomou Michal Koc | 2011 | Mol Cancer2011，10，： | 1 |
| 4 | Can two, four or eight‐hour urine collections after voluntary voiding be used instead of twenty ‐four hour collections for the estimation of creatinine clearance in healthy subjects显示文摘 | Sophia L. Markantonis Eftychia Agathokleous‐Kioupaki | 1998 | Pharmacy World and Science1998，，6： | 1 |
| 5 | Military expenditure and economic growth: A demand and supply model for Greece, 1960-1996 显示文摘 | Paul Dunne Eftychia Nikolaidou | 2001 | Defence and Peace Economics2001，，12： | 1 |
| 6 | Circulating tumor necrosis factor alpha concentrations are higher in abdominal versus peripheral obesity 显示文摘 | Constantine Tsigos Loannis Kyrou Eftychia Chala et at | 1999 | Metabolism1999，48，10： | 1 |
| 7 | Correlation of the Amount of Disc Removed in a Lumbar Microdiscectomy With Long-Term Outcome显示文摘 | Kostas N. Fountas Eftychia Z. Kapsalaki Carlos H. Feltes Hugh F. Smisson Kim W. Johnston Robert L. Vogel Joe S. Robinson | 2004 | Spine2004，，22： | 1 |
| 8 | Automated differentiation of glioblastomas from intracranial metastases using 3T MR spectroscopic and perfusion data显示文摘 | Evangelia Tsolaki Patricia Svolos Evanthia Kousi Eftychia Kapsalaki Konstantinos Fountas Kyriaki Theodorou Ioannis Tsougos | 2013 | International Journal of Computer Assisted Radiology and Surgery2013，，5： | 1 |
| 9 | QT dispersion before and after hemodialysis显示文摘 | SCOTT W M EFTYCHIA G GRAHAM A S | 1999 | J Am Soc Nephrol1999，10，： | 1 |
| 10 | Enhanced recovery in the resection of colorectal liver metastases显示文摘 | Declan F. J. Dunne Vincent S. Yip Robert P. Jones Ewan A. McChesney Daniel T. Lythgoe Eftychia E. Psarelli Louise Jones Carmen Lacasia‐Purroy Hassan Z. Malik Graeme J. Poston Stephen W. Fenwick | 2014 | J. Surg. Oncol2014，，2： | 1 |
| 11 | Circulating tumor necrosis factor alpha concentrations are higher in abdomi-nal versus peripheral obesity 显示文摘 | Constantine Tsigos Loannis Kyrou Eftychia Chala | 1999 | Metabolism1999，48，10： | 1 |
| 12 | Effectiveness of combined tamoxifen citrate and testosterone undecanoate treatment in men with idiopathic oligozoospermia显示文摘 | Dimitrios A Adamopoulos Athina Pappa Evangelia Billa Stamatina Nicopoulou Eftychia Koukkou John Michopoulos | 2003 | Fertility and Sterility2003，，4： | 1 |
| 13 | Left ventricular geometry and systolic function improvementafter percutaneous closure of aortic prosthetic paravalvular leak显示文摘 | Eftychia Demerouti Evangelos Leontiadis George Karatasakis etal | 2013 | The Journal of heart valve disease2013，22，6： | 1 |
| 14 | Effectiveness of combined tamoxifen citrate and testosterone undecanoate treatment in men with idiopathic oligozoospermia显示文摘 | Dimitrios A Adamopoulos Athina Pappa Evangelia Billa Stamatina Nicopoulou Eftychia Koukkou John Michopoulos | 2003 | Fertility and Sterility2003，，4： | 1 |
| 15 | The role of diffusion and perfusion weighted imaging in the differential diagnosis of cerebral tumors: a review and future perspectives 显示文摘 | Patrieia Svolos Evanthia Kousi Eftychia Kapsalaki | 2014 | Cancer Imaging2014，14，1： | 1 |
| 16 | THE DEMAND FOR MILITARY EXPENDITURE: EVIDENCE FROM THE EU15 (1961-2005)显示文摘 | Eftychia Nikolaidou | 2008 | Defence and Peace Economics2008，，4： | 1 |
| 17 | Correlation of the Amount of Disc Removed in a Lumbar Microdiscectomy With Long-Term Outcome显示文摘 | Kostas N. Fountas Eftychia Z. Kapsalaki Carlos H. Feltes Hugh F. Smisson Kim W. Johnston Robert L. Vogel Joe S. Robinson | 2004 | Spine2004，，22： | 1 |
| 18 | Automated differentiation of glioblastomas from intracranial metastases using 3T MR spectroscopic and perfusion data显示文摘 | Evangelia Tsolaki Patricia Svolos Evanthia Kousi Eftychia Kapsalaki Konstantinos Fountas Kyriaki Theodorou Ioannis Tsougos | 2013 | International Journal of Computer Assisted Radiology and Surgery2013，，5： | 1 |
| 19 | Brain lesion classification using 3T MRS spectra and paired SVM kernels显示文摘 | Ioannis Dimou Ioannis Tsougos Evaggelia Tsolaki Evanthia Kousi Eftychia Kapsalaki Kyriaki Theodorou Michalis Kounelakis Michalis Zervakis | 2011 | Biomedical Signal Processing and Control2011，，3： | 1 |
| 20 | COVID-19 and thyroid disease: An infodemiological pilot study显示文摘BACKGROUND Google Trends searches for symptoms and/or diseases may reflect actual disease epidemiology.Recently,Google Trends searches for coronavirus disease 2019(COVID-19)-associated terms have been linked to the epidemiology of COVID-19.Some studies have linked COVID-19 with thyroid disease.AIM To assess COVID-19 cases per se vs COVID-19-associated Google Trends searches and thyroid-associated Google Trends searches.METHODS We collected data on worldwide weekly Google Trends searches regarding“COVID-19”,“severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)”,“coronavirus”,“smell”,“taste”,“cough”,“thyroid”,“thyroiditis”,and“subacute thyroiditis”for 92 wk and worldwide weekly COVID-19 cases'statistics in the same time period.The study period was split in half(approximately corresponding to the preponderance of different SARS-COV-2 virus variants)and in each time period we performed cross-correlation analysis and mediation analysis.RESULTS Significant positive cross-correlation function values were noted in both time periods.More in detail,COVID-19 cases per se were found to be associated with no lag with Google Trends searches for COVID-19 symptoms in the first time period and in the second time period to lead searches for symptoms,COVID-19 terms,and thyroid terms.COVID-19 cases per se were associated with thyroidrelated searches in both time periods.In the second time period,the effect of“COVID-19”searches on“thyroid”searches was significantly mediated by COVID-19 cases(P=0.048).CONCLUSION Searches for a non-specific symptom or COVID-19 search terms mostly lead Google Trends thyroid-related searches,in the second time period.This time frame/sequence particularly in the second time period(noted by the preponderance of the SARSCOV-2 delta variant)lends some credence to associations of COVID-19 cases per se with(apparent)thyroid disease(via searches for them). | Ioannis Ilias Charalampos Milionis Eftychia Koukkou | 2022 | World Journal of Methodology2022，12，3： | 0 |
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