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| 1 | Approach to the endoscopic resection of duodenal lesions显示文摘Duodenal polyps or lesions are uncommonly found on upper endoscopy. Duodenal lesions can be categorized as subepithelial or mucosally-based, and the type of lesion often dictates the work-up and possible therapeutic options. Subepithelial lesions that can arise in the duodenum include lipomas, gastrointestinal stromal tumors, and carcinoids. Endoscopic ultrasonography with fine needle aspiration is useful in the characterization and diagnosis of subepithelial lesions. Duodenal gastrointestinal stromal tumors and large or multifocal carcinoids are best managed by surgical resection. Brunner's gland tumors, solitary Peutz-Jeghers polyps, and non-ampullary and ampullary adenomas are mucosally-based duodenal lesions, which can require removal and are typically amenable to endoscopic resection. Several anatomic characteristics of the duodenum make endoscopic resection of duodenal lesions challenging. However, advanced endoscopic techniques exist that enable the resection of large mucosally-based duodenal lesions. Endoscopic papillectomy is not without risk, but this procedure can effectively resect ampullary adenomas and allows patients to avoid surgery, which typically involves pancreaticoduodenectomy. Endoscopic mucosal resection and its variations(such as cap-assisted, cap-band-assisted, and underwater techniques) enable the safe and effective resection of most duodenal adenomas. Endoscopic submucosal dissection is possible but very difficult to safely perform in the duodenum. | Jonathan P Gaspar Edward B Stelow Andrew Y Wang | 2016 | World Journal of Gastroenterology2016,22,2: | 17 |
| 2 | Epithelial ovarian cancer:An overview显示文摘Ovarian cancer is the second most common gyneco-logical cancer and the leading cause of death in the United States. In this article we review the diagnosis and current management of epithelial ovarian cancer which accounts for over 95 percent of the ovarian malignancies. We will present various theories about the potential origin of ovarian malignancies. We will discuss the genetic anomalies and syndromes that may cause ovarian cancers with emphasis on Breast cancer type 1/2 mutations. The pathology and pathogenesis of ovarian carcinoma will also be presented. Lastly, we provide a comprehensive overview of treatment strategies and staging of ovarian cancer, conclusions and future directions. | Arpita Desai Jingyao Xu Kartik Aysola Yunlong Qin Chika Okoli Ravipati Hariprasad Ugorji Chinemerem Candace Gates Avinash Reddy Omar Danner Geary Franklin Anachebe Ngozi Guilherme Cantuaria Karan Singh William Grizzle Charles Landen Edward E Partridge Valerie Montgomery Rice E Shyam P Reddy Veena N Rao | 2014 | World Journal of Translational Medicine2014,3,1: | 10 |
| 3 | 毛细管电泳法分析蜂花粉中黄酮类化合物(英文)显示文摘使用毛细管电泳法(CE)检测了健康食品中常见的六种黄酮类化合物:橙皮甙、海棠甙、异鼠李素、山奈酚、槲皮素、芦丁。研究了一系列的试验参数,如:pH、缓冲溶液浓度、分离电压以及UV检测器波长等,以确定出最佳条件。使用H3BO3-Na2B4O7缓冲液(pH9.2),各分析物可在8min内分出。相对标准偏差(RSD):8次进样的迁移时间为0.77%~0.93%;峰面积为3.8%~8.6%;各检测限(S/N=3)范围为0.34μg/ml~2.9μg/ml,回收率为80.4%~113.9%。方法简单、灵敏,重现性高,线性好,无须固相萃取前处理,用于蜂花粉分析结果准确。 | 卢挺 Edward P C Lai Jorn C C Yu 胡风祖 | 2006 | 食品科学2006,27,12: | 9 |
| 4 | Nationwide trends and predictors of inpatient mortality in 83884 transjugular intrahepatic portosystemic shunt显示文摘AIM: To evaluate and validate the national trends and predictors of in-patient mortality of transjugular intrahepatic portosystemic shunt(TIPS) in 15 years.METHODS: Using the National Inpatient Sample which is a part of Health Cost and Utilization Project, we identified a discharge-weighted national estimate of 83884 TIPS procedures performed in the United States from 1998 to 2012 using international classification of diseases-9 procedural code 39.1. The demographic, hospital and co-morbility data were analyzed using a multivariant analysis. Using multi-nominal logistic regression analysis, we determined predictive factors related to increases in-hospital mortality. Comorbidity measures are in accordance to the Comorbidity Software designed by the Agency for Healthcare Research and Quality.RESULTS: Overall, 12.3% of patients died during hospitalization with downward trend in-hospitalmortality with the mean length of stay of 10.8 ± 13.1 d. Notable, African American patients(OR = 1.809 vs Caucasian patients, P < 0.001), transferred patients(OR = 1.347 vs non-transferred, P < 0.001), emergency admissions(OR = 3.032 vs elective cases, P < 0.001), patients in the Northeast region(OR = 1.449 vs West, P < 0.001) had significantly higher odds of inhospital mortality. Number of diagnoses and number of procedures showed positive correlations with in-hospital death(OR = 1.249 per one increase in number of procedures). Patients diagnosed with acute respiratory failure(OR = 8.246), acute kidney failure(OR = 4.359), hepatic encephalopathy(OR = 2.217) and esophageal variceal bleeding(OR = 2.187) were at considerably higher odds of in-hospital death compared with ascites(OR = 0.136, P < 0.001). Comorbidity measures with the highest odds of in-hospital death were fluid and electrolyte disorders(OR = 2.823), coagulopathy(OR = 2.016), and lymphoma(OR = 1.842).CONCLUSION: The overall mortality of the TIPS procedure is steadily decreasing, though the length of stay has remained relatively constant. Specific patient ethnicity, location, transfer status, primary diagnosis and comorbidities correlate with increased odds of TIPS in-hospital death. | Edward Wolfgang Lee Andrew Kuei Sammy Saab Ronald W Busuttil Francisco Durazo Steven-Huy Han Mohamed M El-Kabany Justin P Mc Williams Stephen T Kee | 2016 | World Journal of Gastroenterology2016,22,25: | 7 |
| 5 | Through-needle all-optical ultrasound imaging in vivo: a preclinical swine study显示文摘High-frequency ultrasound imaging can provide exquisite visualizations of tissue to guide minimally invasive procedures.Here,we demonstrate that an all-optical ultrasound transducer,through which light guided by optical fibers is used to generate and receive ultrasound,is suitable for real-time invasive medical imaging in vivo.Broad-bandwidth ultrasound generation was achieved through the photoacoustic excitation of a multiwalled carbon nanotube-polydimethylsiloxane composite coating on the distal end of a 300-μm multi-mode optical fiber by a pulsed laser.The interrogation of a high-finesse Fabry–Pérot cavity on a single-mode optical fiber by a wavelength-tunable continuous-wave laser was applied for ultrasound reception.This transducer was integrated within a custom inner transseptal needle(diameter 1.08 mm;length 78 cm)that included a metallic septum to acoustically isolate the two optical fibers.The use of this needle within the beating heart of a pig provided unprecedented realtime views(50 Hz scan rate)of cardiac tissue(depth:2.5 cm;axial resolution:64μm)and revealed the critical anatomical structures required to safely perform a transseptal crossing:the right and left atrial walls,the right atrial appendage,and the limbus fossae ovalis.This new paradigm will allow ultrasound imaging to be integrated into a broad range of minimally invasive devices in different clinical contexts. | Malcolm C Finlay Charles A Mosse Richard J Colchester Sacha Noimark Edward Z Zhang Sebastien Ourselin Paul C Beard Richard J Schilling Ivan P Parkin Ioannis Papakonstantinou Adrien E Desjardins | 2017 | Light(Science & Applications)2017,6,1: | 6 |
| 6 | Annual growth banding in a cave stalagmite显示文摘 | Baker A Smart P Edwards R | 1993 | Nature1993,364,: | 2 |
| 7 | Genetic mapping of 66 new microsatellite(SSR)loci in bread wheat显示文摘 | Gupta P K Balyan H S Edwards K J | 2002 | Theor Appl Genet2002,105,: | 2 |
| 8 | Allocation of carbon permits within a country: a general equilibrium analysis of the United Kingdom显示文摘 | T.Huw Edwards John P Hutton | 2001 | Energy Economics2001,,: | 2 |
| 9 | Comparison of transpiration rates among saltcedar, cottonwood and willow trees by sap flow and canopy temperature methods显示文摘 | PAMELA L Nagler EDWARD P Glenn THOMPSON T Lewis | 2003 | Agri and For Meter2003,116,: | 2 |
| 10 | Apoptosis in the brain of infants suffering intrauterine cerebral injury 显示文摘 | Edwards AD Yue X Cox P | 1997 | Pediatr Res1997,42,6: | 2 |
| 11 | The allocation of risk in PPP/PFI construction projects in the UK 显示文摘 | LI B AKINTOVE A EDWARDS P J | 2005 | International Journal of Project Management2005,,23: | 1 |
| 12 | Genetic mapping of 66 new microsatellite(SSR) loci in bread wheat显示文摘 | Gupta P K Balyan H S Edwards K J | 2002 | Theor Appl Genet2002,105,: | 1 |
| 13 | Epidural analgesia improves outcome after multiple rib fractures显示文摘 | Bttlger EM Edwards T Klotz P | 2004 | Surgery2004,136,2: | 1 |
| 14 | Environmental exposures and gene regulation in disease etiology 显示文摘 | Edwards T M Myers J P | 2007 | Envi Health Pers2007,115,9: | 1 |
| 15 | Researching the Investment of Information Technology in Construction:An Examination of Evaluation Practices 显示文摘 | Iraniz L P Edwards D J | 2005 | Automation in Construction2005,14,8: | 1 |
| 16 | D2 or not D2? The gastrectomy question显示文摘 | Lewis WG Edwards P Jonathan DB | 2002 | Gastric Cancer2002,5,1: | 1 |
| 17 | The central role of wear debris in periprosthetic osteolysis显示文摘 | Edward P Panagiotis K Bryan J N | 2006 | Hospital for Special Surgery Journal2006,2,: | 1 |
| 18 | A method for analyzing plant architecture as it relates to fruit qualibty using three-dimensional computer graphics显示文摘 | Smith G S Curtis J P Edwards C M | 1992 | Annals of Botany1992,70,: | 1 |
| 19 | A test of climate, sun, and culture relationships from an 1 810 year Chinese ca- ve record显示文摘 | Zhang P Z Cheng H Edwards R L | 2008 | Science2008,322,: | 1 |
| 20 | The effect of cultural conditions on growth and secondary metabolism in Streptomycesth ermovilaceus显示文摘 | JAMES P D A EDWARDS C | 1988 | FEMS Microbiol Lett1988,52,: | 1 |