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| 1 | Current trends of liver cirrhosis in Mexico: Similitudes and differences with other world regions显示文摘AIM To investigate the main current etiologies of cirrhosis in Mexico.METHODS We performed a cross-sectional retrospective multicenter study that included eight hospitals in different areas of Mexico. These hospitals provide health care to people of diverse social classes. The inclusion criteria were a histological, clinical, biochemical, endoscopic, or imaging diagnosis of liver cirrhosis. Data were obtained during a 5-year period(January 2012-December 2017). RESULTS A total of 1210 patients were included. The mean age was 62.5 years(SD = 12.1), and the percentages of men and women were similar(52.0% vs 48.0%). The most frequent causes of liver cirrhosis were hepatitis C virus(HCV)(36.2%), alcoholic liver disease(ALD)(31.2%), and nonalcoholic steatohepatitis(23.2%), and the least frequent were hepatitis B virus(1.1%), autoimmune disorders(7.3%), and other conditions(1.0%).CONCLUSION HCV and ALD are the most frequent causes of cirrhosis in Mexico. However, we note that non-alcoholic fatty liver disease(NAFLD) as an etiology of cirrhosis increased by 100% compared with the rate noted previously. We conclude that NAFLD will soon become one of the most frequent etiologies of liver cirrhosis in Mexico. | Nahum Méndez-Sánchez Felipe Zamarripa-Dorsey Arturo Panduro Emma Purón-González Edgar Ulises Coronado-Alejandro Carlos Alejandro Cortez-Hernández Fátima Higuera de la Tijera José Luis Pérez-Hernández Eira Cerda-Reyes Heriberto Rodríguez-Hernández Vania César Cruz-Ramón Oscar Lenin Ramírez-Pérez Nancy Edith Aguilar-Olivos Olga Fabiola Rodríguez-Martínez Samantha Cabrera-Palma Guillermo Cabrera-álvarez | 2018 | World Journal of Clinical Cases2018，6，15： | 2 |
| 2 | Oral insulin delivery 显示文摘 | Gerardo P C Edith M | 1999 | Adv Drug Del Rev1999，35，： | 1 |
| 3 | Nanosphere based oral insulin delivery显示文摘 | Gerardo P C Jules S J Edith M | 2000 | J Controlled Release2000，65，12： | 1 |
| 4 | Oral insulin delivery 显示文摘 | Gerardo P Carino Edith M | 1999 | Advanced Drug Delivery Rev1999，35，： | 1 |
| 5 | Physicochemical and biochemical characterization of starch granules isolated of pigmented maize hybrids显示文摘 | Edith A Ana P B R Guadalupe M | 2008 | Starch2008，60，8： | 1 |
| 6 | Expression and regulation of the human β-defensins hBD-1 and hBD-2 in intestinal epithelium1显示文摘 | Deborah A O'Neil Edith M P | 1999 | J Immunology1999，163，： | 1 |
| 7 | Nanocomposite coatings for healing surface defects of glass fibers and improving interfacial adhesion显示文摘 | GAO S L EDITH M ROSEMARIE P | 2008 | Composites Science and Technology2008，68，14： | 1 |
| 8 | Nanosphere based oral insulin delivery显示文摘 | Gerardo P C Jules S J Edith M | 2000 | J Controlled Release2000，65，12： | 1 |
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