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269篇 您的检索式:作者名="Eakin"
    题名 作者 年代 出处 被引量
1Assessing the Vulnerability of Social-Environmental Systems显示文摘Hallie Eakin Amy Lynd Luers 2006Annual Review of Environment and Resources2006,,:3
2Re-challenge chemotherapy with gemcitabine plus carboplatin in patients with non-small cell lung cancer显示文摘Despite recent improvements to current therapies and the emergence of novel agents to manage advanced non-small cell lung cancer(NSCLC),the patients′overall survival remains poor.Re-challenging with first-line chemotherapy upon relapse is common in the management of small cell lung cancer but is not well reported for advanced NSCLC.NSCLC relapse has been attributed to acquired drug resistance,but the repopulation of sensitive clones may also play a role,in which case re-challenge may be appropriate.Here,we report the results of re-challenge with gemcitabine plus carboplatin in 22 patients from a single institution who had previously received gemcitabine plus platinum in the first-line setting and had either partial response or a progression-free interval of longer than 6 months.In this retrospective study,the charts of patients who underwent second-line chemotherapy for NSCLC in our cancer center between January 2005 and April 2010 were reviewed.All the patients who received a combination of gemcitabine and carboplatin for re-challenge were included in the study.These patients were offered second-line treatment on confirmation of clear radiological disease progression.The overall response rate was 15%and disease control rate was 75%.The median survival time was 10.4 months,with 46%of patients alive at 1 year.These results suggest that re-challenge chemotherapy should be considered in selected patients with radiological partial response or a progression-free survival of longer than 6 months to the initial therapy.Khurum Khan Gerard G Hanna Lynn Campbell Paula Scullin Adnan Hussain Ruth L Eakin Jonathan McAleese 2013Chinese Journal of Cancer2013,32,10:3
3Sources of sedimentary lipids deduced from stable carbon isotope analyses of individual compounds 显示文摘Gareth Rieley Robert J Collier David M Jones Geoffrey Eglinton Paul A Eakin Anthony E Fallick 1991Nature1991,352,:1
4查看详情显示文摘Vardanyan K K Qi J Eakin J N SarkarMD Crawford G P 0,,:1
5Blood glucose control in the trauma patient显示文摘Eakins J 2009J Dia- betes Sci Teehnol2009,3,6:1
6The effects of prostaglandins on the intraocular pressure of the rabbit显示文摘Beitch BR Eakins KE 0,,01:1
7Development of a retrospective/fortuitous accident dosimetry service based on OSL of mobile phones显示文摘Smith RW Eakins JS Hager LG 2015Radiat Prot Dosimetry2015,164,12:1
8Institutional change, climate risk, and rural vulnerabili- ty: Cases from Central Mexico显示文摘Eakin H 2005World Development2005,33,11:1
9Assessing the vulnerability of social-environ- mental systems显示文摘Eakin H Luers A L 2006Annual Review of Environment and Resources2006,31,1:1
10Esti- mating vector autoregressions with panel data显示文摘Holtz - Eakin D Newey W Rosen H S 1988Econo- metrica: Journal of the Econometric Society1988,,:1
11Estimating vector autore- gressions with panel data 显示文摘Holtz- Eakin D Neweyw R 1988Econometrica1988,56,:1
12Estimating vector autoregressions with panel data显示文摘Holta- Eakin D Newey W Rosen H S 1988Econometrica1988,56,6:1
13Phosphorus budget and management strategies for an urban Wisconsin lake 显示文摘James William F Barko John W Eakin Harry L Sorge Patrick W 2002Lake&ReservoirManagement2002,18,2:1
14Review o{ primary care- based physical activity intervention studies: Effectiveness and implications for practice and future research 显示文摘Eakin E Glasgow R Kimberly M 2000Journal of Family Practice2000,49,2:1
15Increased gastro- intestinal permeability and gut inflammation in children with functional abdominal pain and irritable bowel syndrome显示文摘Shulman RJ Eakin MN Czyzewski DI 2008J Pediatr2008,153,5:1
16Validation of the Spanish - language version of the chronic illness resources survey 显示文摘Eakin EG Reeves MM Bull SS 2007Int J Behav Med2007,14,2:1
17Estimating vector au- toregressions with panel data 显示文摘HOLTZ - EAKIN D W NEWEY H S ROSEN 1988Econometrica1988,,56:1
18Stoking the fires? CO2 emis- sions and economic growth 显示文摘HOLTZ -EAKIN D SELDEN T M 1995Journal of Public Economics1995,57,:1
19Radionuclide dating of the recent sediments of Blelham Tarn 显示文摘Pennington W Cambray R S Eakins J D 1976Freshwater Biology1976,,6:1
20Production of crystallizable cruzain,the major cysteine protease from Trypanosoma cruzi显示文摘 McGrath ME McKerrow JH 1993J Biol Chem1993,268,9:1
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