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| 1 | 乳腺管状小叶癌E-cadherin/cate-nin的表达显示文摘 | Esposito N N Chivukula M Dabbs D J 魏兵(摘译) 步宏(审校) | 2007 | 临床与实验病理学杂志2007，23，3： | 8 |
| 2 | Update on surgical treatment of pancreatic neuroendocrine neoplasms显示文摘Pancreatic neuroendocrine neoplasms(PNENs) are rare and account for only 2%-4% of all pancreatic neoplasms. All PNENs are potential(neurendocrine tumors PNETs) or overt(neuroendocrine carcinomas PNECs) malignant,but a subset of PNETs is low-risk. Even in case of low-risk PNETs surgical resection is frequently required to treat hormone-related symptoms and to obtain an appropriate pathological diagnosis. Low-risk PNETs in the body and the tail are ideal for minimallyinvasive approaches which should be tailored to the individual patient. Generally,surgeons must aim for parenchyma sparing in these cases. In high-risk and malignant PNENs,indications for tumor resection are much wider than for pancreatic adenocarcinoma,in many cases due to the relatively benign tumor biology. Thus,patients with locally advanced and metastatic PNETs may benefit from extensive resection. In experienced hands,even multi-organ resections are accomplished with acceptable perioperative morbidity and mortality rates and are associated with excellent long term survival. However,poorly differentiated neoplasms with high proliferation rates are associated with a dismal prognosis and may frequently only be treated with chemotherapy. The evidence on surgical treatment of PNENs stems from reviews of mostly singlecenter series and some analyses of nation-wide tumor registries. No randomized trial has been performed to compare surgical and non-surgical therapies in potentially resectable PNEN. Though such a trial would principally be desirable,ethical considerations and the heterogeneity of PNENs preclude realization of such a study. In the current review,we summarize recent advances in the surgical treatment of PNENs. | Jan G D’Haese Chiara Tosolini Güralp O Ceyhan Bo Kong Irene Esposito Christoph W Michalski J?rg Kleeff | 2014 | World Journal of Gastroenterology2014，20，38： | 4 |
| 3 | Eosinophilic esophagitis: From pathophysiology to treatment显示文摘Eosinophilic esophagitis(Eo E) is a chronic immune disease, characterized by a dense eosinophilic infiltrate in the esophagus, leading to bolus impaction and refluxlike symptoms. Traditionally considered a pediatric disease, the number of adult patients with Eo E is continuously increasing, with a relatively higher incidence in western countries. Dysphagia and food impaction represent the main symptoms complained by patients, but gastroesophageal reflux-like symptoms may also be present. Esophageal biopsies are mandatory for the diagnosis of Eo E, though clinical manifestations and proton pump inhibitors responsiveness must be taken into consideration. The higher prevalence of Eo E in patients suffering from atopic diseases suggests a common background with allergy, however both the etiology and pathophysiology are not completely understood. Elimination diets are considered the firstline therapy in children, but this approach appears less effective in adults patients, who often require steroids; despite medical treatments, Eo E is complicated in some cases by esophageal stricture and stenosis, that require additional endoscopic treatments. This review summarizes the evidence on Eo E pathophysiology and illustrates the safety and efficacy of the most recent medical and endoscopic treatments. | Alessandra D’Alessandro Dario Esposito Marcella Pesce Rosario Cuomo Giovanni Domenico De Palma Giovanni Sarnelli | 2015 | World Journal of Gastrointestinal Pathophysiology2015，6，4： | 4 |
| 4 | In-vivo characterization of DALM in ulcerative colitis with high-resolution probe-based confocal laser endomicroscopy显示文摘Recently,the use of confocal laser endomicroscopy(CLE) in the diagnosis of chronic ulcerative colitis(CUC) was reported.In this brief report we aimed to assess the application of probe-based CLE to characterize colonic mucosa and dysplasia in CUC.The study involved a patient presenting long-standing CUC.Confocal imaging of both the inflamed mucosa,a circumscribed lesion(dysplasiaassociated lesional mass),and adjacent colonic mucosa are demonstrated and the correlation between the CLE and histological images.Inflamed mucosa and dysplasia showed specific alteration of crypt architecture,cellular infiltration,and vessel architecture with an excellent correlation between CLE and standard histological examination. | Giovanni D De Palma Stefania Staibano Saverio Siciliano Francesco Maione Maria Siano Dario Esposito Giovanni Persico | 2011 | World Journal of Gastroenterology2011，17，5： | 3 |
| 5 | ddRAD sequencing-based genotyping for population structure analysis in cultivated tomato provides new insights into the genomic diversity of Mediterranean‘da serbo’type long shelf-life germplasm显示文摘Double digest restriction-site associated sequencing(ddRAD-seq)is a flexible and cost-effective strategy for providing in-depth insights into the genetic architecture of germplasm collections.Using this methodology,we investigated the genomic diversity of a panel of 288 diverse tomato(Solanum lycopersicum L.)accessions enriched in‘da serbo’(called‘de penjar’in Spain)long shelf life(LSL)materials(152 accessions)mostly originating from Italy and Spain.The rest of the materials originate from different countries and include landraces for fresh consumption,elite cultivars,heirlooms,and breeding lines.Apart from their LSL trait,‘da serbo’landraces are of remarkable interest for their resilience.We identified 32,799 high-quality SNPs,which were used for model ancestry population structure and non-parametric hierarchical clustering.Six genetic subgroups were revealed,clearly separating most‘da serbo’landraces,but also the Spanish germplasm,suggesting a subdivision of the population based on type and geographical provenance.Linkage disequilibrium(LD)in the collection decayed very rapidly within<5 kb.We then investigated SNPs showing contrasted minor frequency allele(MAF)in‘da serbo’materials,resulting in the identification of high frequencies in this germplasm of several mutations in genes related to stress tolerance and fruit maturation such as CTR1 and JAR1.Finally,a mini-core collection of 58 accessions encompassing most of the diversity was selected for further exploitation of key traits.Our findings suggest the presence of a genetic footprint of the‘da serbo’germplasm selected in the Mediterranean basin.Moreover,we provide novel insights on LSL‘da serbo’germplasm as a promising source of alleles for tolerance to stresses. | Salvatore Esposito Teodoro Cardi Gabriele Campanelli Sara Sestili María JoséDíez Salvador Soler Jaime Prohens Pasquale Tripodi | 2020 | Horticulture Research2020，7，1： | 2 |
| 6 | Regression of carotid atherosclerosis by control of postprandial hyperglycemia in type 2 diabetes mellitus显示文摘 | Giugliano D Nappo F | 2004 | Circulation2004，110，2： | 1 |
| 7 | Effect of Rosiglitazone on Endothelial Function and Inflammatory Markers in Patients With the Metabolic Syndrome显示文摘 | Esposito K Ciotola Carleo D | | 0，，5： | 1 |
| 8 | Left prefrontal activation during episodic remembering:An event-related fMRI study显示文摘 | JOHNSON M K D'ESPOSITO M | 1998 | NeuroReport1998，，9： | 1 |
| 9 | A comparative analysis of methods for pruning decision trees显示文摘 | ESPOSITO M F D SEMERAROG | 1997 | IEEE Transactions on Pattern Analysis and Machine Intelligence1997，9，5： | 1 |
| 10 | University students' perceptions of the internet: An exploratory study 显示文摘 | D'ESPOSITO J E Gardner R M | 1999 | The Journal of Academic Librarianship1999，25，6： | 1 |
| 11 | Preparation and mechanical properties of edible pectin-soy flour films obtained in the absence or presence of transglutminase显示文摘 | Mariniello L Pierro P D Esposito C | 2003 | J Biotechnol2003，102，： | 1 |
| 12 | Time and frequency domain analysis of electromyogram and sound myogram in the elderly显示文摘 | ESPOSITO F MALGRATI D VEICSTEINAS A | 1996 | Eur J Appl Physiol Occup Physiol1996，73，6： | 1 |
| 13 | Effects of frontal lobe damage on interference effects in working memory显示文摘 | Thompson-Schill S.L John J Marshuetz C Smith E.E D'Esposito M Kan I.P | | 0，，02： | 1 |
| 14 | Primary and secondary prevention of atherosclerosis:is there a role for antiox-idants显示文摘 | Paolisso G Esposito R D′Alessio MA Barbieri M | | 0，，04： | 1 |
| 15 | Heparin-binding hemaggluti-nin HBHA from Mycobacterium tuberculosis affects actin polymeris- ation显示文摘 | Esposito C Marasco D Delogu G | 2011 | Bioehem Biophys Res Commun2011，410，2： | 1 |
| 16 | Role of left inferior prefrontal cortex in retrieval of semantic knowledge:A reevaluation显示文摘 | Thompson-Schill S.L D'Esposito M Aguirre G K Farrah M.J | | 0，，： | 1 |
| 17 | The Synthesis and Characterization of Lipophilic Peptide-based Carriers for Gene Delivery显示文摘 | COLES D J ESPOSITO A CHUAH H T | | 0，，： | 1 |
| 18 | The effect of Mediterranean diet on the development of type 2 diabetes mellitus: A meta-analysis of 10 prospective studies and 136 846 participants显示文摘 | Koloverou E Esposito K Giugliano D | 2014 | Metabolism2014，63，7： | 1 |
| 19 | Cannabidiol reduces in- testinal inflammation through the control of neuroimmune axis显示文摘 | De Filippis D Esposito G Cirillo C | 2011 | PLoS One2011，6，28： | 1 |
| 20 | Cannabidiol:a promising drug for neurodegenerative disorders显示文摘 | Iuvone T Esposito G De Filippis D | | 0，，1： | 1 |
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