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| 1 | Management of Helicobacter pylori infection in Latin America: A Delphi technique-based consensus显示文摘AIM: To optimize diagnosis and treatment guidelines for this geographic region, a panel of gastroenterologists, epidemiologists, and basic scientists carried out a structured evaluation of available literature.METHODS: Relevant questions were distributed among the experts, who generated draft statements for consideration by the entire panel. A modified three-round Delphi technique method was used to reach consensus. Critical input was also obtained from representatives of the concerned medical community. The quality of the evidence and level of recommendation supporting each statement was graded according to United States Preventive Services Task Force criteria.RESULTS: A group of ten experts was established. The survey included 15 open-ended questions that were distributed among the experts, who assessed the articles associated with each question. The levels of agreement achieved by the panel were 50% in the first round, 73.3% in the second round and 100% in the third round. Main consensus recommendations included:(1) when available, urea breath and stool antigen test(HpSA) should be used for non-invasive diagnosis;(2) detect and eradicate Helicobacter pylori(H. pylori) in all gastroscopy patients to decrease risk of peptic ulcer disease, prevent o retard progression in patients with preneoplastic lesions, and to prevent recurrence in patients treated for gastric cancer;(3) further investigate implementation issues and health outcomes of H. pylorieradication for primary prevention of gastric cancer in high-risk populations;(4) prescribe standard 14-d triple therapy or sequential therapy for first-line treatment;(5) routinely assess eradication success post-treatment in clinical settings; and(6) select second- and third-line therapies according to antibiotic susceptibility testing.CONCLUSION: These achievable steps toward better region-specific management can be expected to improve clinical health outcomes. | Antonio Rollan Juan Pablo Arab M Constanza Camargo Roberto Candia Paul Harris Catterina Ferreccio Charles S Rabkin Juan Cristóbal Gana Pablo Cortés Rolando Herrero Luisa Durán Apolinaria García Claudio Toledo Alberto Espino Nicole Lustig Alberto Sarfatis Catalina Figueroa Javier Torres Arnoldo Riquelme | 2014 | World Journal of Gastroenterology2014，20，31： | 2 |
| 2 | Analyzing comprtition between the high speed tran and alternative modes-The case of the Madrid-Zaragoza-Barcelona Corridor显示文摘 | Roman C Espino R Martín J C | 2010 | Journal of Choice Modelling2010，3，1： | 1 |
| 3 | Kidney pelvis hemangioma as a cause of hematuria显示文摘 | Pérez Espejo MP Campoy Martinez P Chinchón Espino D | 2004 | Actas Urol Esp2004，28，6： | 1 |
| 4 | The endo-β-1, 4-xylanase xynllA is required for virulence in Botrytis cinerea显示文摘 | Brito N Espino JJ Gonzalez C | 2006 | Molecular Plant Microbe Interactions2006，19，1： | 1 |
| 5 | Multiple sclerosis patients with anti-lipid oligoclonal IgM show early favourable response to immunomodulatory treatment 显示文摘 | Garcia-Barragan N Villar LM Espino M | 2009 | Eur J Neurol2009，16，3： | 1 |
| 6 | Influence of oligoelonal IgM specificity in multiple sclerosis disease course 显示文摘 | Villar L Garcia-Barragan N Espino M | 2008 | Mult Seler2008，14，2： | 1 |
| 7 | Analyzing competition between the high speed train and alternative modes :the case of the madrid-zaragoza-barcelona corridor显示文摘 | ROMN C ESPINO R MARTIN J C | 2010 | Journal of Choice Modelling2010，3，1： | 1 |
| 8 | Botrytis cinerea endo---l,4-glucanase CeI5A is expressed during infection but is not required for pathogenesis显示文摘 | Espino J J Brito N Noda J | 2005 | Physiological and Molecular Plant Pathology2005，66，6： | 1 |
| 9 | OPV for mobile applications: an evaluation of roll-to-roll processed indium and silver free polymer solar cells through analysis of life cycle, cost and layer quality using inline optical and functional inspection tools 显示文摘 | ESPINOS N LENZMANN F O KREBS F C | 2013 | J Mater ChemA2013，1，24： | 1 |
| 10 | The Botrytis cinereaearly secretome显示文摘 | Espino J J Gutiérrez-Sánchez G Brito N | 2010 | Proteomics2010，10，16： | 1 |
| 11 | Competition of highspeed train with air transport:the case of madrid– barcelona显示文摘 | Roman C Espino R Martín J C | 2007 | Journal of Air Transport Management2007，13，5： | 1 |
| 12 | The Endo-β-1,4-Xyla- nase Xynl 1A is required for virulence in Botrytis cinerea 显示文摘 | Brito N Espino J J Gonza1ez C | 2006 | Molecular Plant-Microbe Interactions2006，19，1： | 1 |
| 13 | The Botrytis cinerea early secretome显示文摘 | Espino J J Guti6rrez-Snchez G Brito N | 2010 | Proteomics2010，10，16： | 1 |
| 14 | Drug-related hepatotoxicity and hepatic failure following combined androgen blockade显示文摘 | Inmaculada Castro Beza Jesús Sánchez Ruiz Francisco José Peracaula Espino M. Isabel Villanego Beltrán | 2008 | Clinical and Translational Oncology2008，，9： | 1 |
| 15 | The Endo-β-1,4-Xyla- nase Xynl 1A is required for virulence in Botrytis cinerea 显示文摘 | Brito N Espino J J Gonza1ez C | 2006 | Molecular Plant-Microbe Interactions2006，19，1： | 1 |
| 16 | Effect of phosphorus addition on unsupported Ni-Mo-W sulfide catalysts prepared by the in situ activation of nickel/tetramethylammonium thiomolybdotungstate显示文摘 | NAVA H ESPINO J BERHAULT G ALONSO-NU(N)EZ G | 2006 | Appl Catal A2006，302，2： | 1 |
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