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8篇 您的检索式:作者名="Peracaula"
    题名 作者 年代 出处 被引量
1Glycoprotein biomarkers for the detection of pancreatic ductal adenocarcinoma显示文摘Pancreatic cancer(Pa C) shows a clear tendency to increase in the next years and therefore represents an important health and social challenge. Currently, there is an important need to find biomarkers for PaC early detection because the existing ones are not useful for that purpose. Recent studies have indicated that there is a large window of time for PaC early detection, which opens the possibility to find early biomarkers that could greatly improve the dismal prognosis of this tumor. The present manuscript reviews the state of the art of the existing PaC biomarkers. It focuses on the anomalous glycosylation process and its role in PaC. Glycan structures of glycoconjugates such as glycoproteins are modified in tumors and these modifications can be detected in biological fluids of the cancer patients. Several studies have found serum glycoproteins with altered glycan chains in PaC patients, but they have not shown enough specificity for PaC. To find more specific cancer glycoproteins we propose to analyze the glycan moieties of a battery of glycoproteins that have been reported to increase in PaC tissues and that can also be found in serum. The combination of these new candidate glycoproteins with their aberrant glycosylation together with the existing biomarkers could result in a panel, which would expect to give better results as a new tool for early diagnosis of PaC and to monitor the disease.Esther Llop Pedro E Guerrero AdriàDuran Sílvia Barrabés Anna Massaguer María JoséFerri Maite Albiol-Quer Rafael de Llorens Rosa Peracaula 2018World Journal of Gastroenterology2018,24,24:4
2Refractory Kawasaki disease with coronary aneurysms treated with infliximab显示文摘Salguero JS Durán DG Peracaula CS 2010An Pediatr(Barc)2010,73,5:1
3Altered glycosylation pattern allows the distinction between prostate-specific antigen (psa) from normal and tumor origins 显示文摘Peracaula R Tabares G Royle L 2003Glycobiology2003,13,6:1
4Role of sialyltransferases involved in the biosynthesis of Lewis antigens in human pancreatic tumour cells 显示文摘Peracaula R Tabares G Lopez-Ferrer A 2005Glycoconj J2005,22,3:1
5Role of sialyltransferases involved in the biosynthesis of Lewis antigens in human pancreatic tumour cells显示文摘Rosa Peracaula Glòria Tabarés Anna López-Ferrer Reinhard Brossmer Carme Bolós Rafael Llorens 2005Glycoconjugate Journal2005,,3:1
6Refractory Kawasakidisease with coronary aneurysms treated with infliximab 显示文摘Salguero JS Duran DG Peracaula CS 2010AnPediatr (Bare)2010,73,5:1
7Drug-related hepatotoxicity and hepatic failure following combined androgen blockade显示文摘Inmaculada Castro Beza Jesús Sánchez Ruiz Francisco José Peracaula Espino M. Isabel Villanego Beltrán 2008Clinical and Translational Oncology2008,,9:1
8Refractory Kawasaki disease with coronary aneurysms treated with infliximab显示文摘Salguero JS Duran DG Peracaula CS 2010An Ped- iatr(Barc)2010,73,5:1
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