|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Nat Biotechnol:将人星形胶质细胞重编程为多巴胺能神经元,有助治疗帕金森病显示文摘帕金森病是一种主要影响运动系统的神经退行性疾病。它的特征在于大脑中的多巴胺能神经元(dopaminergic neuron)渐进性丧失。尽管当前的疗法旨在补充多巴胺水平,但是没有一种疗法能够恢复这些丢失的细胞。如今。在一项新的研究中,来自瑞典、奥地利、西班牙和美国的研究人员开发出一种方法:将神经胶质细胞(glialcell)转化为活性的多巴胺能神经元,并且所产生的多巴胺能神经元能够部分恢复帕金森病模式小鼠的运动功能。这项概念验证研究可能为开发出一种治疗这种疾病的新方法铺平道路。 | Pia Rivetti di Val Cervo, Elisa Martín-Montañez, Enrique M Toledo, Gioele La Manno, Sara Padrell Sánchez, Sten Linnarsson Ernest Arenas Roman A Romanov, Christian Pifl Tibor Harkany Roman A Romanov, Giada Spigolon, Débora Masini, Michael Feyder, Tibor Harkany Gilberto Fisone Elisa Martín-Montañez Yi-Han Ng Marius Wernig | 2017 | 现代生物医学进展2017，17，17： | 11 |
| 2 | Directional distance functions and environmental regulation显示文摘 | Andrés J. Picazo-Tadeo Ernest Reig-Martínez Francesc Hernández-Sancho | 2004 | Resource and Energy Economics2004，，2： | 2 |
| 3 | Field assessment of metal and sulfate fluxes during flooding of pre-oxidized mine tailings 显示文摘 | Lionel J J Ernest K Y Lue S A | 2000 | Advances in Environmental Research2000，4，4： | 1 |
| 4 | Modeling coagulation kinetics incorporating fractal theories:a fractal rectilinear approach显示文摘 | Lee D G Bonner J S Garton L S Ernest A N S Auternrieth R L | 2000 | Water Research2000，34，7： | 1 |
| 5 | Current and futum use of thy-mosin in the treatment of thymosin in the treatment of lung infections显示文摘 | David H Ernest S Ronman A | 1994 | Okla State Med Assoc1994，87，： | 1 |
| 6 | Determination of particle collision efficiencies for flocculent transport models显示文摘 | Ernest A N Bonner J S Aulenrieth R L | 1995 | J of Environmental Engineering1995，121，4： | 1 |
| 7 | Molecular cloning and analysis of two tandemly linked genes for pyruvate kinase of Trypanosoma brucei 显示文摘 | Allert S Ernest I Poliszcak A | 1991 | Eur J Biochem1991，200，： | 1 |
| 8 | Surface parameterization and curvature measurement of arbitrary 3-D objects:five practical methods显示文摘 | ERNEST M S SHANG Y W | 1992 | IEEE Transactions on Pattern Analysis and Machine Intelligence1992，14，8： | 1 |
| 9 | Infection dynamics of Cryptosporidium parvum ( Apicomplexa: Cryptosporiidae) in neonatal mice (Mus musculus) 显示文摘 | ERNEST J A BLAGBURN B L LINDSAY D S | 1986 | J Parasitol1986，72，5： | 1 |
| 10 | Modeling and measurement of evaporation in moisture-retaining soil covers显示文摘 | Ernest K Y Mousavi S M Yang M D | 2003 | Advances in Environmental Research2003，7，： | 1 |
| 11 | Calbistrin E and two other new metabolites from an Australian isolate of Penicillium striatisporum显示文摘 | Michael S Robert J C Ernest L | 2005 | J Nat Prod2005，68，4： | 1 |
| 12 | The effects of surrounding buildings on wind pressure distributions and natural ventilation in long building rows显示文摘 | Bauman F S Ernest D R Arens E A | 1988 | ASHRAE Transactions1988，94，2： | 1 |
| 13 | Expression and function of P -glycoprotein in a mouse kidney cell line显示文摘 | ERNEST S BELLO-REUSS E | 1995 | Am JP hysiol1995，269，： | 1 |
| 14 | Long- term insights into the influence of precipitation on community dynamics in desert rodents显示文摘 | Thibault K M Morgan Ernest S K White E P | 2010 | Journal of Mamrnalogy2010，91，4： | 1 |
| 15 | A national survey of Aus tralian ICU liaison nurse services显示文摘 | Eliott S Chaboyer W Ernest D et a l | 2012 | Australian Critical Care2012，25，4： | 1 |
| 16 | Factors affecting the shear strength of mine tailings/clay mixtures with varying clay 显示文摘 | ROZALINA S ERNEST K | 2012 | Engineering geology2012，125，4： | 1 |
| 17 | The AcrySof Toric intraocular lens in subjects with cataracts and corneal astigmatism: a randomized, subject-masked, parallelgroup, I-year study 显示文摘 | Holland E Lane S Hom JD Ernest P Arleo R Miller KM | 2010 | Ophthalmology2010，117，11： | 1 |
| 18 | Conjugation of (E) -5- cytidine to hydrophilic mierospheres:Development of a mobile mi- croscale UV light actinometer显示文摘 | Fang S Y Guan Y S Ernest R Blatchley | 2008 | Bioconjugate Chem2008，19，： | 1 |
| 19 | FSI Implications of EMC Rheological Properties to 3D IC with TSV Structures During Plastic Encapsulation Process显示文摘 | ERNEST E S O ABDULLAH W K | 2013 | Microelectronics Reliability2013，51，： | 1 |
| 20 | Complex species interactions and the dynamics of ecological systems: Long-term experiments显示文摘 | Brown J H Whithmu T G M Ernest S K | 2001 | Science2001，293，5530： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员