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| 1 | Nat Biotechnol:将人星形胶质细胞重编程为多巴胺能神经元,有助治疗帕金森病显示文摘帕金森病是一种主要影响运动系统的神经退行性疾病。它的特征在于大脑中的多巴胺能神经元(dopaminergic neuron)渐进性丧失。尽管当前的疗法旨在补充多巴胺水平,但是没有一种疗法能够恢复这些丢失的细胞。如今。在一项新的研究中,来自瑞典、奥地利、西班牙和美国的研究人员开发出一种方法:将神经胶质细胞(glialcell)转化为活性的多巴胺能神经元,并且所产生的多巴胺能神经元能够部分恢复帕金森病模式小鼠的运动功能。这项概念验证研究可能为开发出一种治疗这种疾病的新方法铺平道路。 | Pia Rivetti di Val Cervo, Elisa Martín-Montañez, Enrique M Toledo, Gioele La Manno, Sara Padrell Sánchez, Sten Linnarsson Ernest Arenas Roman A Romanov, Christian Pifl Tibor Harkany Roman A Romanov, Giada Spigolon, Débora Masini, Michael Feyder, Tibor Harkany Gilberto Fisone Elisa Martín-Montañez Yi-Han Ng Marius Wernig | 2017 | 现代生物医学进展2017，17，17： | 11 |
| 2 | Surface parameterization and curvature measurement of arbitrary 3-D objects:five practical methods显示文摘 | ERNEST M S SHANG Y W | 1992 | IEEE Transactions on Pattern Analysis and Machine Intelligence1992，14，8： | 1 |
| 3 | Modeling and measurement of evaporation in moisture-retaining soil covers显示文摘 | Ernest K Y Mousavi S M Yang M D | 2003 | Advances in Environmental Research2003，7，： | 1 |
| 4 | Long- term insights into the influence of precipitation on community dynamics in desert rodents显示文摘 | Thibault K M Morgan Ernest S K White E P | 2010 | Journal of Mamrnalogy2010，91，4： | 1 |
| 5 | Complex species interactions and the dynamics of ecological systems: Long-term experiments显示文摘 | Brown J H Whithmu T G M Ernest S K | 2001 | Science2001，293，5530： | 1 |
| 6 | Effects of eyestalk ablationon larval molting rates and morphological development ofthe Americanl obster (Homarus americanus) 显示文摘 | SNYDER M J ERNEST S C | 1986 | Biol Bull1986，170，2： | 1 |
| 7 | Surface parametrization and curvature measurement of arbitrary 3-D objects:five practical methods显示文摘 | Ernest M S Shang Y W | 1992 | IEEE PAMI1992，14，8： | 1 |
| 8 | Rodent, plant,and precipitation: spatial and temporal dynamics of consumers and resource显示文摘 | Ernest S K M Brown J H Parmenter R R | 2000 | Oikos2000，88，3： | 1 |
| 9 | Performance of a single lookup table (LUT) for displaying chest CT images 显示文摘 | Ajo J Walter H Ernest S M Kent O M Roskopf M L | 2004 | Academic Radiology2004，11，6： | 1 |
| 10 | Species-level and community-level re- sponses to disturbance : A cross-community analysis 显示文摘 | Supp S R Ernest S K M | 2014 | Ecolo- gy2014，95，： | 1 |
| 11 | Hot-strip method for simultanesouly measuring thermal conductivity and thermal diffusivity of solids and fluids 显示文摘 | Gustafsson S E Karawack Ernest Khan M N | 1979 | Appl Phys1979，112，05： | 1 |
| 12 | Application of fractal flocculation and vertical transport model to aquatic sol-sediment systems显示文摘 | Sterling M C J S Bonner A N S Ernest | 2005 | Water Research2005，39，： | 1 |
| 13 | Aplication of fractal flocculation and vertical transport model to aquatic sol-sediment systems显示文摘 | Sterling M C J S Bonner A N S Ernest | 2005 | Water Research2005，39，： | 1 |
| 14 | Integrated guidance and control of missiles with θ -D method显示文摘 | M Xin S N Balakrishnan Ernest J Ohlmeyer | 2006 | IEEE Transactions on Control Systems Technology2006，14，6： | 1 |
| 15 | Species identification of Tanzanian antelopes using DNA barcoding显示文摘 | Bitanyi S Bjornstad G Ernest E M | 2011 | Mol Ecol Resour2011，11，3： | 1 |
| 16 | Effects of chronic exposure to an environmentally relevant mixture of brominated flame retardants on the reproductive and thyroid system in adult male rats 显示文摘 | Ernest S R Wade M G Lalancette C | 2012 | Toxicol Sci2012，127，2： | 1 |
| 17 | Effects of chronic ex- posure to an environmentally relevant mixture of hrominated flame retardants on the reproductive and thyroid system in adult male rats 显示文摘 | Ernest S R Wade M G Lalancette C | 2012 | Toxicol Sci2012，127，2： | 1 |
| 18 | Removal ofthiophene impurities from benzene by selective adsorption in zeolite ZSM-5显示文摘 | Weitkamp J Schwark M Ernest S | 1991 | J Chem Soc Chem Commun1991，，： | 1 |
| 19 | Tissue kallikrein and kininogen levels in fetoplacental tissues from normotensive pregnant women and women with pregnancy-induced hypertension显示文摘 | Mahaneem M Ernest T L Harbindar J S | | 0，，01： | 1 |
| 20 | Modulation of lipid synthesis,apolipoprotein biogenesis,and lipoprotein assembly by butyrate显示文摘 | Valrie M Edgard D Ernest S | 2002 | Am J PhysiolGastrointest Liver Physiol2002，283，： | 1 |
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