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| 1 | DC-derived IL-18 drives Treg differentiation, murine Helicobacter pylori-specific immune tolerance, and asthma protection显示文摘 | Oertli Mathias Sundquist Malin Hitzler Iris Engler Daniela B Arnold Isabelle C Reuter Sebastian Maxeiner Joachim Hansson Malin Taube Christian Quiding-J?rbrink Marianne Müller Anne | 2012 | EN2012，，3： | 5 |
| 2 | Matrix Elasticity Directs Stem Cell Lineage Specification显示文摘 | Adam J. Engler Shamik Sen H. Lee Sweeney Dennis E. Discher | 2006 | Cell2006，，4： | 4 |
| 3 | 肥胖、高血压和体力运动决定儿童的血管表型显示文摘心血管病常在儿童时期引发,但是儿童血管健康和疾病的决定因素还不清楚。该研究旨在探讨儿童肥胖、高血压、体能与视网膜微血管健康以及大动脉僵硬度之间的关系。在该横断面研究中,通过标准化的程序来评估1171名小学生[年龄(7.2±0.4)岁]的视网膜中央小动脉直径(central retinal arteriolarequivalent, CRAE)和视网膜中央静脉直径(centralretinal venular equivalent, CRVE)、脉搏波传导速度(pulse wave velocity, PWV)、体质量指数(body massindex,BMI),血压和心肺耐力。 | 陈嘉睿 练桂丽 K?chli S Endes K Steiner R Engler L Infanger D Schmidt-Trucksǎss Zahner L Hanssen H | 2019 | 中华高血压杂志2019，27，4： | 3 |
| 4 | Murine model to study brain,behavior and immunity during hepatic encephalopathy显示文摘AIM:To propose an alternative model of hepatic encephalopathy(HE) in mice,resembling the human features of the disease.METHODS:Mice received two consecutive intraperitoneal injections of thioacetamide(TAA) at low dosage(300 mg/kg).Liver injury was assessed by serum transaminase levels(ALT) and liver histology(hematoxylin and eosin).Neutrophil infiltration was estimated by confocal liver intravital microscopy.Coagulopathy was evaluated using prolonged prothrombin and partial thromboplastin time.Hemodynamic parameters were measured through tail cuff.Ammonia levels were quantified in serum and brain samples.Electroencephalography(EEG) and psychomotor activity score were performed to show brain function.Brain edema was evaluated using magnetic resonance imaging.RESULTS:Mice submitted to the TAA regime developed massive liver injury,as shown by elevation of serum ALT levels and a high degree of liver necrosis.An intense hepatic neutrophil accumulation occurred in response to TAA-induced liver injury.This led to mice mortality and weight loss,which was associated with severe coagulopathy.Furthermore,TAA-treated mice presented with increased serum and cerebral levels of ammonia,in parallel with alterations in EEG spectrum and discrete brain edema,as shown by magnetic resonance imaging.In agreement with this,neuropsychomotor abnormalities ensued 36 h after TAA,fulfilling several HE features observed in humans.In this context of liver injury and neurological dysfunction,we observed lung inflammation and alterations in blood pressure and heart rate that were indicative of multiple organ dysfunction syndrome.CONCLUSION:In summary,we describe a new murine model of hepatic encephalopathy comprising multiple features of the disease in humans,which may provide new insights for treatment. | Lindisley Ferreira Gomides Pedro Elias Marques Bruno Engler Faleiros Rafaela Vaz Pereira Sylvia Stella Amaral Thais Reis Lage Gustavo Henrique Souza Resende Patricia Alves Maia Guidine Giselle Foureaux Fabíola Mara Ribeiro Fabiana Paiva Martins Marco Antonio Peliky Fontes Anderson José Ferreira Remo Castro Russo Mauro Martins Teixeira Márcio Flávio Moraes Antonio Lúcio Teixeira Gustavo Batista Menezes | 2014 | World Journal of Hepatology2014，6，4： | 2 |
| 5 | Role of leukocytes in response to acute myocardial ischemic and reflow in dogs显示文摘 | Engler RL Dahlgren MD Morris DD | 1986 | Am J Physiol1986，，： | 1 |
| 6 | Short term effects of atorvatatin on c-reactive protein显示文摘 | Riesen W F Engler H Risch M | 2002 | Eur Heart J2002，23，10： | 1 |
| 7 | Reperfusion injury induces apoptosis in rabbit cardiomyocytes显示文摘 | Gottlieb RA Burleson KO Kloner RA Babior BM Engler RL | | 0，，： | 1 |
| 8 | DLR PSP system intensity and lifetime measurements显示文摘 | Engler R H Klein Chr | 1997 | Instrumentation in Aerospace Simulation Facilities1997，29，2： | 1 |
| 9 | Matrix elasticity directs stem cell lineage specification显示文摘 | Engler AJ Sen S Sweeney HL | 2006 | Cell2006，126，4： | 1 |
| 10 | Reduction in left ventricular messenger RNA for transforming growth factor-β1 attenuates left ventricu fibrosis and improves survival without lowering blood pressure in the hypertensive TGR (mRen2) 27 rat显示文摘 | Pinto Y Philipp T Engler S | 2000 | Hypertension2000，36，5： | 1 |
| 11 | RacerX: Effective, static detection of race conditions and deadlocks显示文摘 | Engler D Ashcraft K | 2003 | SIGOPS Oper Syst Rev2003，37，5： | 1 |
| 12 | Short term effects of atorvastatin on C-reactive protein显示文摘 | Riesen WF Engler H Risch M | 2002 | Eur Heart J2002，23，： | 1 |
| 13 | Phytophthora parasitica bio film formation: installation and organization of microcolonies on the surface of a host plant显示文摘 | Galiana E Fourre S Engler G | 2008 | Environ Microbiol2008，10，8： | 1 |
| 14 | On the influence of orientation pinning on growth selection of recrystallization显示文摘 | Engler O | 1998 | Acta Materialia1998，46，： | 1 |
| 15 | Influence of particles on recrystallization textures and microstructures of ahuninium alloy 3103 显示文摘 | VATNE H E ENGLER O NES E | 1997 | Materials Science and Technology1997，13，2： | 1 |
| 16 | Comparative study of diets enriched with evening primrose, black currant, borage or fungal oils on blood pressure and pressor responses in spontaneously hypertensive rats 显示文摘 | Engler M M | 1993 | Prostaglandins Leukotrienes and Essential Fatty Acids1993，49，： | 1 |
| 17 | Texture control by thermomeehanieal processing of AA6 > xxx A1-Mg-Si sheet alloys for automotive applications--a review 显示文摘 | Engler O Hirsch J | 2002 | Materials Science and Engineering A2002，336，1： | 1 |
| 18 | Tissue-specific expression and developmental regulation of cytochrome b561 genes in Arabidopsis thaliana and Raphartus sativus显示文摘 | Verelst W Kapila J De Almeida Engler J | 2004 | Physiol Plant2004，120，2： | 1 |
| 19 | Co-Integration and Error Correction: Repre-sentation, Estimation, and Testing显示文摘 | EngleR F Granger CW | 1987 | Econometrica: Journal of theEconometric Society1987，，16： | 1 |
| 20 | Immunogenicity of two accelerated hepatitis B vaccination protocols in liver transplant candidates显示文摘 | Engler SH Sauer PW Golling M | 2001 | Eur J Gastroenterol Hepatol2001，13，4： | 1 |
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