|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Exploring the role of molecular biomarkers as a potential weapon against gastric cancer: a review of the literature显示文摘Gastric cancer(GC) is a global health problem and a major cause of cancer-related death with high recurrence rates ranging from 25% to 40% for GC patients staging Ⅱ-Ⅳ. Unfortunately, while the majority of GC patients usually present with advanced tumor stage; there is still limited evidence-based therapeutic options. Current approach to GC management consists mainly of; endoscopy followed by, gastrectomy and chemotherapy or chemo-radiotherapy. Recent studies in GC have confirmed that it is a heterogeneous disease. Many molecular characterization studies have been performed in GC. Recent discoveries of the molecular pathways underlying the disease have opened the door to more personalized treatment and better predictable outcome. The identification of molecular markers is a useful tool for clinical managementin GC patients, assisting in diagnosis, evaluation of response to treatment and development of novel therapeutic modalities. While chemotherapeutic agents have certain physiological effects on the tumor cells, the prediction of the response is different from one type of tumor to the other. The specificity of molecular biomarkers is a principal feature driving their application in anticancer therapies. Here we are trying to focus on the role of molecular pathways of GC and well-established molecular markers that can guide the therapeutic management. | Marwa Matboli Sarah El-Nakeep Nourhan Hossam Alaa Habieb Ahmed EM Azazy Ali E Ebrahim Ziad Nagy Omar Abdel-Rahman | 2016 | World Journal of Gastroenterology2016，22，26： | 2 |
| 2 | A New Clean Process for Barium Carbonate Preparation by Barite Reduction with Methane显示文摘 | Jamshidi E Ale Ebrahim H | 2008 | Chemical Engineering and Processing2008，47，： | 1 |
| 3 | Photosynthetic performance and adaptation of sugarcane at suboptimal temperatures显示文摘 | Ebrahim M K H Vogg G Osman M N E H Komor E | 1988 | Journal of Plant Physiology1988，153，5： | 1 |
| 4 | Synergy of slow photon and chemically amplified photochemistry in plati- num nanocluster-loaded inverse titania opals 显示文摘 | Chen J I L Loso E Ebrahim N | 2008 | Journal of American Chemical Society2008，130，： | 1 |
| 5 | 查看详情显示文摘 | Chen J. I. L Loso E Ebrahim N Ozin G.A | | 0，，： | 1 |
| 6 | Performance evaluation of two RO membrance configurations in an MSF/R0 hybrid system显示文摘 | El-Sayed E Abdel-Jawad M Ebrahim S and A1-Saffar A | 2000 | DeJalmaHon2000，，128： | 1 |
| 7 | Synergy of slow photon and chemically amplified photochemistry in platinum nanocluster-loaded inverse titania opals 显示文摘 | Chen J I Loso E Ebrahim N | 2008 | Journal of the American Chemical Society2008，130，16： | 1 |
| 8 | Rehabilitating role of glutathione ester on cisplatin induced nephrotoxicity显示文摘 | Babu E Ebrahim AS Chandramohan N | 1999 | Ren Fail1999，21，2： | 1 |
| 9 | Optimum active vehicle suspensions with actuator time delay显示文摘 | Nader J Ebrahim E | 2001 | Transactions of the ASME2001，123，： | 1 |
| 10 | A comparison of theupper Lip bite test〈 a simple new technique) with modifiedmallampati classfication in prediciting difficulty in endotrachealintubation:a prospective blinded study显示文摘 | Khan Z H Kashfi A Ebrahim Khani E | 2003 | Anesthesia &Analgesia2003，96，2： | 1 |
| 11 | The relationship of detrusor instability and symptoms with objective parameters used for diagnosing bladder outlet obstruction:a prospective study显示文摘 | Wadie B S Ebrahim E E Gomha M A | 2002 | J Urol2002，168，1： | 1 |
| 12 | Equilibrium, kinetic, and thermodynamic biosorption of Pb ( lI ), Cr(RI), and Cd ( 1I ) ions by dead anaerobic biomass from synthetic wastewater 显示文摘 | SULAYMON A H EBRAHIM S E MOHAMMED-RIDHA M J | 2013 | Environmental Science and Pollution Research2013，20，1： | 1 |
| 13 | Carotid plaque, inti- ma media thickness, cardiovascular risk {actors, and prevalent cardiovascular disease in men and women: the British regional heart study显示文摘 | Ebrahim E Papacosta O Whincup P | 1999 | Stroke1999，30，4： | 1 |
| 14 | Carotid Plaque,ln- tima Media Thickness, Cardiovascular Risk Factors, and Prevalent Cardiovascular Disease in Men and Women:The British Regional Heart Study 显示文摘 | Shah Ebrahim Olia Papaeosta Whineup e't al | 1999 | Stroke1999，30，4： | 1 |
| 15 | Power control and management in a hybrid AC/DC microgrid显示文摘 | Navid E Ebrahim F | 2014 | IEEE Transaction on Smart Grid2014，5，3： | 1 |
| 16 | Effect of Melatonin on Proliferative Activity and Apoptosis in Spermatogenic Cells in Mouse under Chemotherapy显示文摘Objective To investigate the possible protective role of melatonin on the proliferative activity, and apoptosis of germ cells in chemotherapy-induced spermiotoxicity. Methods Male adult NMRI mice were divided into four groups. Then each group was divided into two subgroups of a and b. Group A (control): mice received vehicle (1% ethanol) for 5 d. Group B (busulfan): mice received a single dose of 20 mg/kg busulfan. Group C (melatonin): mice received melatonin (10 mg/kg) for 5 d. Group D (busulfan+melatonin): mice received a 5-day course of melatonin (10 mg/kg) following an initial dose of busulfan (20 mg/kg). Evaluations were made using bromodeoxyuridine (BrdU) labeling and in situ TUNEL assay after 5 d (subgroup a) or 35 d (subgroup b). Results Busulfan-treated mice both in subgroups a and b, showed a significant increase in the number of apoptotic cells (P<0.01) and decrease in BrdU labeling index (P<0.01) compared with controls. Melatonin in group C significantly decreased BrdU labeling index compared with the control (P<0.01). Melatonin in group D significantly reduced apoptosis rate and increased BrdU labeling index compared with group B. Conclusion Melatonin may have a protective effect against busulfan-induced testicular damage, partly by decreasing of apoptosis and alteration in proliferative activity of germ cells. | Fahimeh Mohamad Ghasemi Masoumeh Faghani Sina Khajehjahromi Mohamadhadi Bahadori Ebrahim Nasiri E Masoud Hemadi | 2010 | Journal of Reproduction and Contraception2010，21，2： | 1 |
| 17 | Vibration analysis and design optimization of sandwich beams with constrained vis- coelastic core layer显示文摘 | JASROBIN S G RAMIN S EBRAHIM E | | Journal of Sandwich Structures and Ma terials0，15，2： | 1 |
| 18 | Comparison of theassociations of body mass index and measures of central adiposity andfat mass with coronary heart disease, diabetes, and all-causemortality:A study using data from 4 UK cohorts 显示文摘 | TaylorA E Ebrahim S Ben-Shlomo Y | 2010 | Am J ClinNutr2010，91，3： | 1 |
| 19 | Measuring serum levels of glycosaminoglycans for prediction and using viscum fraxini-2 for treatment of patients with hepatocellular carcinoma 显示文摘 | A1-Gayyar M M H Ebrahim M A Shams M E E | 2013 | J Pharm Res2013，7，7： | 1 |
| 20 | Cast shadow segmentation using invariant color features 显示文摘 | Salvador E Cavallaro A Ebrahim T I | 2004 | Computer Vision and Image Understanding2004，95，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员