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| 1 | 犯罪制图:理解犯罪热点(中)显示文摘理解犯罪热点需要具备一定的理论基础,需要相关犯罪理论的指导。理解犯罪热点具有多种方法和技术。在介绍各种方法和技术并指出各自优缺点的基础上,指出犯罪制图技术在理解犯罪热点上的显著重要性。识别犯罪热点需要借助一定的空间分析工具,各种空间分析工具具有自身特定的优缺点及不同的用途。为防止出现主观性和随意性,犯罪热点分析应考虑多种因素,以科学的方法实施。 | 郑滋椀 金诚 John E.Eck Spencer Chainey James G.Cameron Michael Leitner Ronald E.Wilson | 2012 | 预防青少年犯罪研究2012，，5： | 9 |
| 2 | 犯罪制图:理解犯罪热点(上)显示文摘理解犯罪热点需要具备一定的理论基础,需要相关犯罪理论的指导。理解犯罪热点具有多种方法和技术。在介绍各种方法和技术并指出各自优缺点的基础上,指出犯罪制图技术在理解犯罪热点上的显著重要性。识别犯罪热点需要借助一定的空间分析工具,各种空间分析工具具有自身特定的优缺点及不同的用途。为防止出现主观性和随意性,犯罪热点分析应考虑多种因素,以科学的方法实施。 | 郑滋椀 金诚 John E.Eck Spencer Chainey James G.Cameron Michael Leitner Ronald E.Wilson | 2012 | 预防青少年犯罪研究2012，，4： | 5 |
| 3 | Meta‐analysis of randomized controlled trials on the safety and effectiveness of early versus delayed laparoscopic cholecystectomy for acute cholecystitis显示文摘 | K.Gurusamy K.Samraj C.Gluud E.Wilson B. R.Davidson | 2010 | Br J Surg2010，，2： | 3 |
| 4 | 犯罪制图:理解犯罪热点(下)显示文摘理解犯罪热点需要具备一定的理论基础,需要相关犯罪理论的指导。理解犯罪热点具有多种方法和技术。在介绍各种方法和技术并指出各自优缺点的基础上,指出犯罪制图技术在理解犯罪热点上的显著重要性。识别犯罪热点需要借助一定的空间分析工具,各种空间分析工具具有自身特定的优缺点及不同的用途。为防止出现主观性和随意性,犯罪热点分析应考虑多种因素,以科学的方法实施。 | 郑滋椀 金诚 John E.Eck Spencer Chainey James G.Cameron Michael Leitner Ronald E.Wilson | 2012 | 预防青少年犯罪研究2012，，6： | 2 |
| 5 | Functionality of dietary antimicrobial peptides in aquatic animal health:Multiple meta-analyses显示文摘Effects of antimicrobial peptides(AMP)added to diets on aquatic animal health and body function are influenced by multiple factors such as animal species,initial body weight,the dosage of AMP and feeding duration.However,there is limited knowledge on the relationship between these factors and the body function of aquatic animals.Here,we aimed to perform multiple meta-analyses to investigate the effects of dietary AMP on growth performance(feed conversion ratio[FCR],specific growth rate[SGR]),enzyme activity(superoxide dismutase activity[SOD],lysozyme activity[LSA]),disease resistance(cumulative survival rate[CSR],the expression of immune-related genes[GENE])and the abundance of gut microbiota(MICRO)from a pool of empirical studies.Additionally,the dose-effect model was applied to determine the optimal AMP dose,initial body weight and feeding duration to maximize body function.To conduct the meta-analyses,we included 34 publications that estimated 705 effect sizes across 21 fish,2 shrimp and 2 shellfish species.The results confirmed that the inclusion of AMP in the diet can significantly improve SGR,SOD,LSA,CSR and GENE and decrease FCR for aquatic animals.Interestingly,our findings implied a slight positive effect of AMP on MICRO albeit with a limited number of studies available on fish gut microbial communities.Although no significant linear or quadratic relationship was predicted by meta-regression,the dose-effect indicated that the optimal AMP doses for FCR,SGR,SOD and LSA were 707.5,750.0,1,050.0 and 937.5 mg/kg,respectively.Taken together,fish with an initial body weight of 30 g could be fed with a dose of 600 to 800 mg/kg for 2 mo when AMP-supplemented diets were applied in aquaculture,which can effectively improve body function and health while lowering aquafeed costs.In addition,more studies should address fish gut microbiota to delimitate the influence of dietary AMP on MICRO in the future. | Jinhai Wang Alan E.Wilson Baofeng Su Rex A.Dunham | 2023 | Animal Nutrition2023，，1： | 2 |
| 6 | 近视患者用准分子激光作角膜切削术后角膜地形图的改变显示文摘17例近视患者在准分子激光切削术后第一年中进行了计算机辅助的角膜地形图的分析。角膜中央视区进行了自然过渡到周边角膜的切削。在一些眼出现切削偏中心(3眼小于0.5mm,10眼为0.5~1.0mm,3眼为1~1.5mm,1眼为2.1mm),说明瞄准光束是非常重要的。有待改进使切削中心位于瞳孔中心。17眼中的12眼在PRK术后3~7个月内角膜地形图非常稳定,其余的5眼在6~12个月的随访时,发现中央屈光度的改变大于0.5D。在矫正度大于5D的患者中矫正回退比较常见,而大多数期望矫正度≤(?)D的眼中,中央切削度与预期矫正的度数间有很好的重合性。2只眼由于不规则散光、偏中心和角膜混浊。最好的矫正视力至少下降2行。 | Steven E.Wilson Stephen D.Klyce 瞿小妹 | 1993 | 国外医学(眼科学分册)1993，17，5： | 1 |
| 7 | Meta‐analysis of randomized controlled trials on the safety and effectiveness of early versus delayed laparoscopic cholecystectomy for acute cholecystitis显示文摘 | K.Gurusamy K.Samraj C.Gluud E.Wilson B. R.Davidson | 2010 | Br J Surg2010，，2： | 1 |
| 8 | Cost–utility and value‐of‐information analysis of early versus delayed laparoscopic cholecystectomy for acute cholecystitis显示文摘 | E.Wilson K.Gurusamy C.Gluud B. R.Davidson | 2010 | Br J Surg2010，，2： | 1 |
| 9 | Dry Eye and Corneal Sensitivity After High Myopic LASIK显示文摘 | IlpoS.Tuisku Nina Lindbohm Steven E.Wilson | | 0，，04： | 1 |
| 10 | Effects of purposeful soccer heading on circulating small extracellular vesicle concentration and cargo显示文摘Background:Considering the potential cumulative effects of repetitive head impact(HI)exposure,we need sensitive biomarkers to track shortand long-term effects.Circulating small extracellular vesicles(sEVs)(<200 nm)traffic biological molecules throughout the body and may have diagnostic value as biomarkers for disease.The purpose of this study was to identify the microRNA(miRNA)profile in circulating sEVs derived from human plasma following repetitive HI exposure.Methods:Healthy adult(aged 18-35 years)soccer players were randomly assigned to one of 3 groups:the HI group performed 10 standing headers,the leg impact group performed 10 soccer ball trapping maneuvers over 10 min,and the control group did not participate in any soccer drills.Plasma was collected before testing and 24 h afterward,and sEVs were isolated and characterized via nanoparticle tracking analysis.Next-generation sequencing was utilized to identify candidate miRNAs isolated from sEVs,and candidate microRNAs were analyzed via quantitative polymerase chain reaction.In silico target prediction was performed using TargetScan(Version 7.0;targetscan.org)and miRWalk(http://gffzzd93d5b8fada64be9hpwnb9vxkknon6ukc.ffgz.tsg.suse.edu.cn/)programs,and target validation was performed using luciferase reporter vectors with a miR-7844-5p mimic in human embryonic kidney(HEK)293T/17 cells.Results:Plasma sEV concentration and size were not affected across time and group following repetitive HI exposure.After 24 h,the HI read count from next-generation sequencing showed a 4-fold or greater increase in miR-92b-5p,miR-423-5p,and miR-24-3p and a 3-fold or greater decrease in miR-7844-5p,miR-144-5p,miR-221-5p,and miR-22-3p.Analysis of quantitative polymerase chain reaction revealed that leg impact did not alter the candidate miRNA levels.To our knowledge,miR-7844-5p is a previously unknown miRNA.We identified 8 miR-7844-5p mRNA targets:protein phosphatase 1 regulatory inhibitor subunit 1B(PPP1R1B),LIM and senescent cell antigen-like domains 1(LIMS1),autophagy-related 12(ATG12),microtubule-associated protein 1 light chain 3 beta(MAP1LC3B),integrin subunit alpha-1(ITGA1),mitogenactivated protein kinase 1(MAPK1),glycogen synthase kinase 3b(GSK3b),and mitogen-activated protein kinase 8(MAPK8).Conclusion:Collectively,these data indicate repetitive HI exposure alters plasma sEV miRNA content,but not sEV size or number.Furthermore,for the first time we demonstrate that previously unknown miR-7844-5p targets mRNAs known to be involved in mitochondrial apoptosis,autophagy regulation,mood disorders,and neurodegenerative disease. | Eric R.Munoz Jaclyn B.Caccese Brittany E.Wilson Kyle T.Shuler Fernando V.Santos Carolina T.Caban John J.Jeka Dianne Langford Matthew B.Hudson | 2021 | Journal of Sport and Health Science2021，10，2： | 1 |
| 11 | 激光原位角膜磨镶术和屈光性角膜消融术后伤口愈合反应—个体化激光视力矫正后难以控制的生物学多样性和效应显示文摘伤口愈合反应中的生物学多样性被认为是限制屈光手术,比如激光原位角膜磨镶术和屈光性角膜消融术的结果可预测性的主要因素。角膜伤口的愈合是影响角膜地形图或波阵面引导的准分子激光切削以达到最优视力成功的关键因素。这是因为维持个体化切削后的细微特点的重要性、上皮增生和基质的重新塑型倾向掩盖了这些特点。角膜的伤口愈合反应是极其复杂的。出现在上皮损伤反应中的角膜细胞的凋亡是在伤口愈合时最早可观察到的情况,也因此成为药物介入治疗的最佳靶位。改变手术技术的设计可以限制角膜细胞的凋亡和随后出现在伤口愈合中的一些情况。串联的异常可能是造成角膜疾病的病因。比如,最近的数据表明对角膜细胞的凋亡/有丝分裂平衡的扰动可能是部分患者形成圆锥角膜的潜在因素。 | Steven E.Wilson 金红颖 等 | 2002 | 美国医学会眼科杂志(中文版)2002，14，1： | 1 |
| 12 | Twin peaks: finding fragile sites with MiDAS-seq显示文摘Two papers from Macheret et al.and Ji et al.describe novel high-resolution direct sequencing approaches to map fragile sites and hundreds of additional genomic regions that can remain under-replicated prior to mitotic entry and complete replication in mitosis.They further establish many defining properties of these loci that greatly add to our mechanistic understanding of fragile sites and genome instability following replication stress. | Thomas W.Glover Thomas E.Wilson | 2020 | Cell Research2020，30，11： | 0 |
| 13 | 子宫内烟草烟雾暴露与成年女性血浆血脂、ApoB和CRP的关联显示文摘[背景]最近的研究结果表明,孕妇妊娠期间吸烟可能在其后代儿童期代谢的变化中发挥作用。然而,这种暴露是否增加成年期类似代谢改变的风险尚不确定。[目的]评估子宫内烟草烟雾暴露与成年期血浆血脂、载脂蛋白B(apoB)和c.反应蛋白(CRP)之间的关联。[方法]研究基于挪威母子队列研究(MoBa)的子样本,检测了479名孕妇的血脂、apoB和CRP。约在妊娠17周,通过入组孕妇完成自评问卷,获得有关子宫内烟草烟雾暴露、个人吸烟史及其他因素的有关信息。[结果]校正年龄、体力活动、教育、个人吸烟和体质指数(BMI)后,与无暴露的女性相比,在子宫内暴露于烟草烟雾的女性三酰甘油水平较高[升高10.7%,95%可信区间(CI):3.9%.17.9%],高密度脂蛋白胆固醇(HDL)水平较低(一1.9mg/L,95%CI:一4.3~0.5mg/L)。烟草烟雾暴露的女性三酰甘油≥2000mg/L[‘校正比值比(aOR)=2.5,95%C1:1.3~5.1],和HDL〈500mg/L(aOR=2.3,95%C1:1.1~5.0)的可能性更大。低密度脂蛋白胆固醇、总胆固醇和apoB与暴露无关联。暴露女性的CRP升高,然而经BMI校正后,相关性完全消失。[结论]在该人群中,子宫内暴露于烟草烟雾与成年期(暴露1844年后)高三酰甘油及低HDL相关。 | Lea A.Cupul-Uicab Rolv Skjaerven Kjell Haug Gregory S.Travlos Ralph E.Wilson Merete Eggesb Jane A.Hoppin Kristina W.Whitworth Matthew P.Longnecker | 2013 | 环境与职业医学2013，30，2： | 0 |
| 14 | 最佳估算加不确定性安全分析技术发展的历史观显示文摘美国商用核反应堆执照申请的相关要求,最初是建立在认为最成问题的事故工况、保守安全限值以及规定的分析方法基础之上。然而,上世纪80年代,大量的试验分析研究以及反应堆的实际运行经验表明,最初过于保守的方法在一定程度上有误导,有时甚至给出并不保守的结果。因此,开发一套基于风险的执照申请安全分析策略的需求日益增加。首个成功的方法则为研究院开发的程序缩比模拟,应用不确定性分析(CSAU)、现象识别和分级方法(PIRT),并为美国核管会的安全监管部门所接受。此套策略通常被称为最佳估算加不确定性分析方法(BEPU)。本文给出CSAU与PIRT的历史见解以及直至2010年最佳估算加不确定性分析方法的发展情况。 | Gary E.Wilson | 2013 | 国外核动力2013，，1： | 0 |
| 15 | Hospitalizations and healthcare costs associated with serious, non-lethal firearm-related violence and injuries in the United States, 1998-2011显示文摘Objective:To describe the prevalence,trends,correlates,and short-term outcomes of inpa-tient hospitalizations for firearm-related injuries(FRIs)in the United States between 1998 and 2011.Methods:We conducted a retrospective,cross-sectional analysis of inpatient hospitalizations using data from the Nationwide Inpatient Sample.In addition to generating national prevalence estimates,we used survey logistic regression to calculate odds ratios(ORs)and 95%confidence intervals(CIs)for the association between FRIs and patient/hospital-level characteristics.Tempo-ral trends were estimated and characterized using joinpoint regression.Results:There were 10.5 FRIs(95%CI:9.2-11.8)per 10,000 non-maternal/neonatal inpatient hospitalizations,with assault accounting for 60.1%of FRIs,followed by unintentional/accidental(23.0%)and intentional/self-inflicted FRIs(8.2%).The highest odds of FRIs,particularly FRIs associated with an assault,was observed among patients 18-24 years of age,patients 14-17 years of age,patients with no insurance/self-pay,and non-Hispanic blacks.The mean inpatient length of stay for FRIs was 6.9 days;however,4.7%of patients remained in the hospital over 24 days and 1 in 12 patients(8.2%)died before discharge.The mean cost of an inpatient hospitalization for a FRI was$22,149,which was estimated to be$679 million annually;approximately two-thirds of the annual cost(64.7%)was for assault($439 million).Conclusion:FRIs are a preventable public health issue which disproportionately impacts younger generations,while imposing significant economic and societal burdens,even in the ab-sence of fatalities.Prevention of FRIs should be considered a priority in this era of healthcare cost containment. | Jason L.Salemi Vikas Jindal RoneéE.Wilson Mulubrhan F.Mogos Muktar H.Aliyu Hamisu M.Salihu | 2015 | Family Medicine and Community Health2015，3，2： | 0 |
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