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您的检索式：作者名="E.A. Mitchell"
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| 1 | 早产儿与足月儿的SIDS危险因素是否不同显示文摘Background: Mortality from SIDS has declined since the recommendation that infants are not placed prone to sleep. SIDS mortality is higher in infants born preterm than those born at term. Aim: To determine if risk factors for SIDS are any different for preterm and term infants. Methods: Mortality data over time were used to determine whether the reduction in SIDS mortality rates had occurred equally in term and preterm infants. Data from two New Zealand studies (a case-control study and a case-cohort study)were used to determine if any differences existed in risk factors for SIDS between term and preterm infants before and after the SIDS prevention campaign. Results: SIDS mortality appears to have decreased by similar proportions in term and preterm infants. Risk factors for SIDS were similar in preterm and term infants, except for parity where there was a significant interaction. Increasing parity was a risk factor for SIDS in term infants but not preterm infants. Conclusion: SIDS rates have decreased at comparable rates in term and preterm infants, but preterm birth still remains a risk factor for SIDS. The magnitude of the odds ratios associated with modifiable risk factors were similar for both groups. There may however be a difference in risk associated with parity between term and preterm infants. The messages for risk factors for SIDS are applicable to mothers of preterm as well as term infants. | Thompson J.M.D. Mitchell E.A. 张振 | 2006 | 世界核心医学期刊文摘(儿科学分册)2006，0，9： | 0 |
| 2 | 母乳喂养与学龄前儿童的智力水平显示文摘Aim: To investigate whether breastfeeding during infancy is a determinant of i ntelligence at 3.5 y. Methods: Five hundred and fifty European children enrolled at birth in the Auckland Birthweight Collaborative Study were assessed at 3.5 y of age. Approximately half were small for gestational age (SGA < 10th percentil e) at birth and half were appropriate for gestational age (AGA > 10th percentile ). Duration of breastfeeding was recorded at maternal interview, and the intelli gence of children was assessed using the Stanford Binet Intelligence Scale. Regr ession analysis was used to calculate estimates of difference in intelligence sc ores between breastfeeding groups for the total sample and the group of SGA chil dren. Analyses of the total sample were weighted to account for the disproportio nate sampling of SGA children. Results: Breastfeeding was not significantly rela ted to intelligence scores in the total sample despite a trend for longer period s of breastfeeding to be associated with higher intelligence scores. However, in the SGA group, breastfeeding was significantly related to IQ at 3.5 y. Small fo r gestational age children who were breastfed for longer than 12 mo had adjusted scores 6.0 points higher than those who were not breastfed (p = 0.06). Conclusi on: Breastfeeding may be particularly important for the cognitive development of preschool children born small for gestational age. | Slykerman R.F. Thompson J.M.D. Becroft D.M.O. E.A. Mitchell 张振 | 2006 | 世界核心医学期刊文摘(儿科学分册)2006，0，1： | 0 |
| 3 | 60例蕈样肉芽肿和Sézary综合征患者淋巴结的分子学疾病分期:组织病理学与研究结果相关联提示与蕈样肉芽肿的预后有关显示文摘Background: Histological evidence of lymph node involvement is associated with a poor prognosis in patients with cutaneous T-cell lymphoma (CTCL). Objectives: To determine whether T-cell receptor (TCR) gene analysis is of prognostic relevance in CTCL. Methods: TCR gene analysis was performed on lymph node specimens from 60 patients with mycosis fungoides (MF) and Sézary syndrome (SS) using a highly sensitive polymerase chain reaction (PCR)/single-strand conformational polymorphism analysis and results were correlated with skin, overall clinical and histological lymph node stages. Results: The frequency with which a T-cell clone was detected in lymph node samples from patients with MF increased with skin stage, overall clinical stage and with the degree of histological involvement: six of 19 patients with uninvolved lymph nodes or limited histological involvement (LN0-2) and 13 of 14 patients with advanced histological involvement (LN3-4) had a detectable T-cell clone. In SS, 22 of 27 patients had a detectable lymph node T-cell clone. The clonal patients had a poorer prognosis than nonclonal patients (median survival from biopsy of > 72 months vs. 16 months for MF and 41.5 vs. 16.5 months for SS). Regression analysis confirmed that TCR gene analysis identifies a group of MF patients with a worse prognosis (P = 0.013). However, the molecular lymph node stage did not provide independent prognostic information in this cohort of patients in multivariate analysis. Conclusions: Molecular staging in MF and SS using a PCR-based method for TCR gene analysis provides additional information to histological examination. Specifically, this study identified a group of MF patients with early lymph node involvement with a poorer prognosis. However, a larger prospective study of patients with MF and early histological lymph node involvement is required to confirm whether molecular staging of lymph nodes provides independent prognostic information in a multivariate model. | Fraser-Andrews E.A. Mitchell T. Ferreira S. 周少娜 | 2006 | 世界核心医学期刊文摘(皮肤病学分册)2006，，12： | 0 |
| 4 | 随机对照试验:综合医疗中应用一种治疗小儿哮喘的临床途径效果 | Mitchell E.A. Didsbury P.B. Kruithof N. 李开 | 2005 | 世界核心医学期刊文摘(儿科学分册)2005，0，8： | 0 |
| 5 | 发达国家孕妇饮食状况对小于胎龄分娩儿风险的影响:病例对照研究 | Mitchell E.A. Robinson E. Clark P.M. 张振 | 2005 | 世界核心医学期刊文摘(儿科学分册)2005，0，2： | 0 |
| 6 | 不明病因的胎盘绒毛炎:流行病学报道 | Becroft D.M Thompson J.M. Mitchell E.A. 高雪莲 | 2005 | 世界核心医学期刊文摘(妇产科学分册)2005，0，6： | 0 |
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