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74篇 您的检索式：作者名="Durrant G"

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	题名	作者	年代	出处	被引量
1	Cytoplasmic expression of p27^(kip1) is associated with a favourable prognosis in colorectal cancer patients显示文摘AIM: To evaluate the prognostic significance of p27kip1 in colorectal cancer patients. METHODS: Cytoplasmic and nuclear p27kip1 expression was evaluated in 418 colorectal cancers using tissue microarrays. Data were associated with known patient and tumor variables and long-term patient outcomes, providing further insight into the mechanisms by which p27kip1 may influence tumor development. RESULTS: Nuclear and cytoplasmic p27Kip1 expressions were detected in 59% and 19% of tumors respectively. Cytoplasmic p27Kip1 was almost invariably associated with positive nuclear p27Kip1 expression. Neither case correlat- ed with known clinical or pathological variables, includ- ing tumor stage, grade or extramural vascular invasion. Furthermore, nuclear p27kip1 expression had no impact on survival. However, we identified a significant correla- tion between expression of cytoplasmic p27kip1 and longer disease-specific survival times. On multivariate analysis, TNM stage and extramural vascular invasion were highly significant independent prognostic factors, with positive cytoplasmic p27 expression showing a trend towards im- proved patient survival (P = 0.059).CONCLUSION: These findings support the recent evi- dence that cytoplasmic p27kip1 has a distinct and impor- tant biological role that can influence tumor outcome.	Nicholas FS Watson Lindy G Durrant John H Scholefield Zahra Madjd Duncan Scrimgeour Ian Spendlove Ian O Ellis Poulam M Patel	2006	World Journal of Gastroenterology2006，12，39：	3
2	Structural and optical properties of amorphous hydrogenated fluorinated carbon films produced by PECVD显示文摘	DURRANT S F CASRO S G C BOLAVAR-MARINEZ L E	1997	Thin Solid Films1997，304，12：	1
3	The role of CD55 in protecting the tumour environment from complement attack显示文摘	Morgan J Spendlove I Durrant L G	2002	Tissue Antigens2002，60，3：	1
4	Development of cancer vaccines to activate cytotoxic T lymphocytes 显示文摘	Durrant L G Ramage J M	2005	Expert Opin Biol Ther2005，5，4：	1
5	The squeeze casting of hypoeutectic binary Al-Cu显示文摘	GALLERNEAULT M DURRANT G CANTOR B	1996	Metall and Mater Trans A1996，27，：	1
6	The relationship between capsid protein(VP2)sequence and pathogenicity of Aleutian mink disease parvovirus(ADV):apossible role for raccoons in the transmission of ADV infections显示文摘	Oie K L Durrant G Wolfinbarger J B Martin D Costello F Perrman S Hogan D Hadolw W J Bloom M E	1996	J Virol1996，70，2：	1
7	显示文摘	Gull G Durrant L Stainer C el al	1999	Br J Haematol1999，107，3：	1
8	cDNA - AFLP reveals a striking overlap in race - specific resistance and wound response gene expression profiles显示文摘	Durrant W E Rowland O Piedras P Kosack K E H Jones J D G	2000	Plant Cell2000，12，6：	1
9	Associated nuclear changes in the induction of flax genotrophs 显示文摘	EVANS G M DURRANT A Rees H	1966	Nature1966，212，：	1
10	Effect of sodium fertilizers on water status and yield of sugar beet 显示文摘	DURRANT M J DRAYCOTF A P MILFORD G E J	1978	Ann Appl Biol1978，88，：	1
11	Enhanced expression of the complement regulatory protein CD55 predicts a poor prognosis in colorectal cancer patients显示文摘	Durrant L G	2003	Cancer Immunol Immunother2003，52，10：	1
12	Towards Terrain-aided Navigation for Underwater Robotics显示文摘	Williams S Dissanayake G Durrant W H	2001	Advanced Robotics2001，15，5：	1
13	Measurement of thermal stratification in large singlecell buildings显示文摘	Said M N A MacDonald R A Durrant G C	1996	Energy and Buildings1996，24，2：	1
14	Characterization of reinforcement distribution in cast Al-Alloy/SiCp composites显示文摘	KAMEZIS P A DURRANT G CANTOR B	1998	Materials Characterization1998，40，2：	1
15	The role of CD55 in protecting the tumor environment from complement attack 显示文摘	Morgan J Spendlove I Durrant L G	2002	Tissue Antigens2002，60，3：	1
16	Furnace implosions and explosions显示文摘	Durrant O W Lansing E G	1976	Proceedings of the American Power Conference1976，38，：	1
17	The squeeze casting of hypoeutectic binary Al Cu显示文摘	GALLERNEAUL T M DURRANT G CANTOR B	1996	Metallurgical and Mate- rials Transactions1996，27，12：	1
18	Effect of sodium fertilizer on water status and yield of sugar beet显示文摘	Durrant M J Draycott A P Milford G F J	1978	Annual of Applied Biology1978，88，：	1
19	Furnace implosions and explosions 显示文摘	Durrant O W Lansing E G	1976	Proceedings of the American Power Conference1976，，38：	1
20	The rdationship be- tween capsid protein ( VP2 ) sequence and pathogenicity of Aleu- tian mink disease parvovirus (ADV) : a possible role for raccoons in thetransmission of ADV infections 显示文摘	Qie K L ' Durrant G i Woh~nbarger J B	1996	Journal of Virology1996，70，2：	1

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