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| 1 | Bile acids as global regulators of hepatic nutrient metabolism显示文摘Bile acids(BA)are synthesized from cholesterol in the liver.They are essential for promotion of the absorption of lipids,cholesterol,and lipid-soluble vitamins from the intestines.BAs are hormones that regulate nutrient metabolism by activating nuclear receptors(farnesoid X receptor(FXR),pregnane X receptor,vitamin D)and G protein-coupled receptors(e.g.,TGR5,sphingosine-1-phosphate receptor 2(S1PR2))in the liver and intestines.In the liver,S1PR2 activation by conjugated BAs activates the extracellular signal-regulated kinase 1/2 and AKT signaling pathways,and nuclear sphingosine kinase 2.The latter produces sphingosine-1-phosphate(S1P),an inhibitor of histone deacetylases 1/2,which allows for the differential up-regulation of expression of genes involved in the metabolism of sterols and lipids.We discuss here the emerging concepts of the interactions of BAs,FXR,insulin,S1P signaling and nutrient metabolism. | Phillip B.Hylemon Kazuaki Takabe Mikhail Dozmorov Masayuki Nagahashi Huiping Zhou | 2017 | Liver Research2017，1，1： | 3 |
| 2 | Global gene expression analysis of human bronchial epithelial cells treated with tobacco condensates 显示文摘 | Jorgensen E D Dozmorov I Frank M B | 2004 | Cell Cycle2004，3，： | 1 |
| 3 | Gene expression profile of long-lived snell dwarf mice显示文摘 | Dozmorov I Galecki A Chang Y | | 0，，： | 1 |
| 4 | Identification of unique microRNA signature associated with lupus nephritis显示文摘 | Te JL Dozmorov IM Guthridge JM | | 0，，： | 1 |
| 5 | Differenti-ally expressed gene networks in cultured smooth muscle cellsfrom normal and neuropathic bladder显示文摘 | DOZMOROV MG KROPP BP HURST RE | 2007 | J Smooth Muscle Res2007，43，2： | 1 |
| 6 | Identification of unique microRNA signature associated with lupus nephritis 显示文摘 | Te JL Dozmorov IM Guthridge JM | 2010 | PLoS One2010，5，10： | 1 |
| 7 | Identification of u- nique microRNA signature associated with lupus nephritis显示文摘 | Te JL Dozmorov IM Guthridge JM | 2010 | PLoS One2010，5，10： | 1 |
| 8 | Contribution of AMPA and NMDA receptors to early and late phases of LTP in hippoc ampal slices显示文摘 | Dozmorov M Li R Abbas AK | 2006 | Nenrosci Res2006，55，： | 1 |
| 9 | Identification of unique microRNA signature associated with lupus nephritis显示文摘 | Te JL Dozmorov IM Guthridge JM | 2010 | PLoS One2010，5，10： | 1 |
| 10 | Osteoblasts produce soluble factors that induce a gene expression pattern in non-metastatic prostate cancer cells similar to that found in bone metastatic prostate cancer cells 显示文摘 | Fu Z Dozmorov I Keller E | 2002 | Prostate2002，51，： | 1 |
| 11 | Genome-wide DNAmethylation patterns in CD4+ T cells from patients with systemiclupus erythematosus显示文摘 | Jeffries MA Dozmorov M Tang Y | 2011 | Epigenetics2011，6，5： | 1 |
| 12 | Identification of u- nique microRNA signature associated with lupus nephritis显示文摘 | Te JL Dozmorov IM Guthridge JM | 2010 | PLoS One2010，5，10： | 1 |
| 13 | The curcuminoid CLEFMA selectively induces ceil death in H441 lung adenocarcinoma cells via oxidative stress 显示文摘 | Sahoo K Dozmorov MG Anant S | 2012 | Invest New Drugs2012，30，： | 1 |
| 14 | Elevated AKR1C3 expression promotes prostate cancer cell survival and prostate cell-mediated endothelial cell tube formation: im- plications for prostate cancer progression显示文摘 | Dozmorov MG Azzarello JT Wren JD | 2010 | BMC Cancer2010，10，： | 1 |
| 15 | Identification of uniquemicroRNA signature associated with lupus nephritis 显示文摘 | Te JL?Dozmorov IM Guthridge JM | 2010 | PLoSOne2010，5，10： | 1 |
| 16 | Identification of unique microRNA signature associated with lupus nephritis显示文摘 | Te JL Dozmorov IM Guthridge JM | | 0，，05： | 1 |
| 17 | Elevated AKR1C3 expression promotes prostate cancer cell survival and prostate cellmediated endothelial cell tube formation:implications for prostate cancer progression显示文摘 | Dozmorov MG Azzarello JT Wren JD | | 0，，： | 1 |
| 18 | Identification of unique microRNA signature associated with lupus nephritis 显示文摘 | Te JL Dozmorov IM Guthridge JM | 2010 | PLoS One2010，115，10： | 1 |
| 19 | Elevated AKR1C3 ex- pression promotes prostate cancer cell survival and prostate cell-medi- ated endothelial cell tube formation: implications for prostate cancer progressioan显示文摘 | Dozmorov MG Azzarello JT Wren JD | 2010 | BMC Cancer2010，10，6： | 1 |
| 20 | Genome-wide DNA methylation patterns in CD4 + T ceils from patients with systemic lupus erythematosus显示文摘 | Jeffries M Dozmorov M Tang Y | 2011 | Epigenetics2011，6，： | 1 |
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