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38篇 您的检索式:作者名="Doeppner"
    题名 作者 年代 出处 被引量
1Mi-croRNA-124 protects against focal cerebral ischemia via mechanisms involving Usp14-dependent REST degradation显示文摘Doeppner TR Doehring M Bretschneider E Zechariah A Kaltwasser B Müller B Koch JC B?hr M Hermann DM Michel U 0,,:1
2Transduction of neural precursor cells with TAT-heat shock protein 70 chaperone: therapeutic potential against ischemic stroke after intrastriatal and systemic transplantation 显示文摘Doeppner TR Ewert TA Tonges L 2012Stem Cells2012,30,6:1
3Vascular endothelial growth factor promotes pericyte coverage of brain capillaries, improves cerebral blood flow during subsequent focal cerebral ischemia, and preserves the metabolic penumbra 显示文摘Zechariah A Elali A Doeppner T R 2013stroke2013,44,:1
4Increased blood-brain barrier permeability and brain edema after focal cerebral ischemia induced by hyperlipidemia: role of lipid peroxidation and calpain-1/2,matrix metallo- proteinase-2/9, and RhoA overactivation显示文摘Ayman Elali Thorsten R Doeppner Anil Zechariah 2011Stroke2011,42,11:1
5Acute hepa- tocyte growth factor treatment induces long-term neuro- protection and stroke recovery via mechanisms involving neural precursor cell proliferation and differentiati0n显示文摘Doeppner TR Kaltwasser B Elali AA 2011J Cereb Blood Flow Metab2011,31,5:1
6Protection of hippocampal neurogenesis by TAT-Bcl-xL after cerebral ischemia in mice显示文摘Doeppner TR Dietz GP Weise J 0,,02:1
7Cold-induced apoptosis of rat liver endothelial cells:involvement of the proteasome显示文摘DOEPPNER T R GRUNE T DE-GROOT H 2003Transplantation2003,75,12:1
8Stem cell-based treatments against stroke: observations from human proof-of-concept studies and considerations regarding clinical applicability 显示文摘Doeppner TR Hermann DM 2014Front Cell Neurosci2014,8,:1
9Vascular endothelial growth factor promotes pericyte coverage of brain capillaries, improves cerebral blood flow during subsequent focal cerebral ischemia, and preserves the metabolic penumbra显示文摘Zechariah A Elali A Doeppner TR 2013Stroke2013,44,6:1
10Increased Blood-brain barrier permeability and brain edema after focal cerebral ischemia induced by hyperlipidemia 显示文摘AYMAN ELALI THORSTEN T DOEPPNER 2011Stroke2011,11,:1
11Modulating poststroke inflammatory mechanisms: Novel aspects of mesenchymal stem cells, extracellular vesicles and microglia显示文摘Inflammation plays an important role in the pathological process of ischemic stroke,and systemic inflammation affects patient prognosis.As resident immune cells in the brain,microglia are significantly involved in immune defense and tissue repair under various pathological conditions,including cerebral ischemia.Although the differentiation of M1 and M2 microglia is certainly oversimplified,changing the activation state of microglia appears to be an intriguing therapeutic strategy for cerebral ischemia.Recent evidence indicates that both mesenchymal stem cells(MSCs)and MSC-derived extracellular vesicles(EVs)regulate inflammation and modify tissue repair under preclinical stroke conditions.However,the precise mechanisms of these signaling pathways,especially in the context of the mutual interaction between MSCs or MSC-derived EVs and resident microglia,have not been sufficiently unveiled.Hence,this review summarizes the state-ofthe-art knowledge on MSC-and MSC-EV-mediated regulation of microglial activity under ischemic stroke conditions with respect to various signaling pathways,including cytokines,neurotrophic factors,transcription factors,and microRNAs.Wen-Qiang Xin Wei Wei Yong-Li Pan Bao-Long Cui Xin-Yu Yang Mathias Bähr Thorsten R Doeppner 2021World Journal of Stem Cells2021,13,8:1
12Effects of neural progenitor cells on post-stroke neurological impairment-a detailed and comprehensive analysis of behavioral tests 显示文摘Doeppner TR Kaltwasser B Bahr M 2014Front Cell Neurosci2014,8,:1
13Free radical scavengers and spin traps - therapeutic implications for ischemic stroke 显示文摘Doeppner TR Hermann DM 2010Best Pract Res Clin Anaesthesiol2010,24,4:1
14Free radical scavengers and spin traps-therapeutic implications for ischemic stroke显示文摘Doeppner TR Hermann DM 0,,04:1
15TAT-Bcl-x (L) improves survival of neuronal precursor cells in the lesioned striatum after focal cerebral ischemia 显示文摘Doeppner TR Dietz GP El Aanbouri M 2009Neurobiol Dis2009,34,1:1
16Increased blood-brain barrier permeability and brain edema after focal cerebral ischemia induced by hyperlipidemia:role of lipid peroxidation and calpain-1/2,matrix metal-loproteinase-2/9,and RhoA overactivation显示文摘ElAli A Doeppner TR Zechariah A 2008Stroke2008,42,11:1
17Vascular endothelial growth factor promotes pericyte coverage of brain capillaries, improves cerebral blood flow during subsequent focal cerebral ischemia, and preserves the metabolic penumbra显示文摘Zechariah A Elali A Doeppner TR 2013Stroke2013,44,6:1
18Vascular endothelial growth factor promotes pericyte coverage of brain capillaries, improves cerebral blood flow during subsequent focal cerebral ischemia and preserves the metabolic penumbra显示文摘Zechariah A Elali A Doeppner TR 2013Stroke2013,30,4:1
19TAT-Bcl-xL improves survival of neuronal precursor cells in the lesioned striatum after focal cerebral ischemia显示文摘Doeppner TR Dietz GP E1 Aanbouri M 2009Neurobiol Dis2009,34,1:1
20Protection of hippocampal neurogenesis by TAT-Bel-xL after eerebral isehemia in mice 显示文摘Doeppner TR Dietz GP Weise J 2010Exp Neurol2010,223,2:1
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