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| 1 | Consensus statement AIGO/SICCR diagnosis and treatment of chronic constipation and obstructed defecation(Part Ⅱ:Treatment)显示文摘The second part of the Consensus Statement of the Italian Association of Hospital Gastroenterologists and Italian Society of Colo-Rectal Surgery reports on the treatment of chronic constipation and obstructed defecation.There is no evidence that increasing fluid intake and physical activity can relieve the symptoms of chronic constipation.Patients with normal-transit constipation should increase their fibre intake through their diet or with commercial fibre.Osmotic laxatives may be effective in patients who do not respond to fibre supplements.Stimulant laxatives should be reserved for patients who do not respond to osmotic laxatives.Controlled trials have shown that serotoninergic enterokinetic agents,such as prucalopride,and prosecretory agents,such as lubiprostone,are effective in the treatment of patients with chronic constipation.Surgery is sometimes necessary.Total colectomy with ileorectostomy may be considered in patients with slow-transit constipation and inertia coli who are resistant to medical therapy and who do not have defecatory disorders,generalised motility disorders or psychological disorders.Randomised controlled trials have established the efficacy of rehabilitative treatment in dys-synergic defecation.Many surgical procedures may be used to treat obstructed defecation in patients with acquired anatomical defects,but none is considered to be the gold standard.Surgery should be reserved for selected patients with an impaired quality of life.Obstructed defecation is often associated with pelvic organ prolapse.Surgery with the placement of prostheses is replacing fascial surgery in the treatment of pelvic organ prolapse,but the efficacy and safety of such procedures have not yet been established. | Antonio Bove Massimo Bellini Edda Battaglia Renato Bocchini Dario Gambaccini Vincenzo Bove Filippo Pucciani Donato Francesco Altomare Giuseppe Dodi Guido Sciaudone Ezio Falletto Vittorio Piloni | 2012 | World Journal of Gastroenterology2012，18，36： | 33 |
| 2 | Consensus statement AIGO/SICCR:Diagnosis and treatment of chronic constipation and obstructed defecation(partⅠ:Diagnosis)显示文摘Chronic constipation is a common and extremely troublesome disorder that significantly reduces the quality of life,and this fact is consistent with the high rate at which health care is sought for this condition.The aim of this project was to develop a consensus for the diagnosis and treatment of chronic constipation and obstructed defecation.The commission presents its results in a 'Question-Answer' format,including a set of graded recommendations based on a systematic review of the literature and evidence-based medicine.This section represents the consensus for the diagnosis.The history includes information relating to the onset and duration of symptoms and may reveal secondary causes of constipation.The presence of alarm symptoms and risk factors requires investigation.The physical examination should assess the presence of lesions in the anal and perianal region.The evidence does not support the routine use of blood testing and colonoscopy or barium enema for constipation.Various scoring systems are available to quantify the severity of constipation;the Constipation Severity Instrument for constipation and the obstructed defecation syndrome score for obstructed defecation are the most reliable.The Constipation-Related Quality of Life is an excellent tool for evaluating the patient's quality of life.No single test provides a pathophysiological basis for constipation.Colonic transit and anorectal manometry define the pathophysiologic subtypes.Balloon expulsion is a simple screening test for defecatory disorders,but it does not define the mechanisms.Defecography detects structural abnormalities and assesses functional parameters.Magnetic resonance imaging and/or pelvic floor sonography can further complement defecography by providing information on the movement of the pelvic floor and the organs that it supports.All these investigations are indicated to differentiate between slow transit constipation and obstructed defecation because the treatments differ between these conditions. | Antonio Bove Filippo Pucciani Massimo Bellini Edda Battaglia Renato Bocchini Donato Francesco Altomare Giuseppe Dodi Guido Sciaudone Ezio Falletto Vittorio Piloni Dario Gambaccini Vincenzo Bove | 2012 | World Journal of Gastroenterology2012，18，14： | 20 |
| 3 | Prevention of vertical transmission of hepatitis B virus infection显示文摘Hepatitis B virus(HBV)is the leading cause of chronic viral hepatitis.Annually,almost two million children younger than 5 years acquire the infection,mostly through vertical or horizontal transmission in early life.Vertical transmission of HBV is a high efficacy phenomenon ranging,in the absence of any preventive interventions,from 70%to 90%for hepatitis e antigen positive mothers and from 10%to 40%for hepatitis e antigen-negative mothers.Maternal viraemia is a preeminent risk factor for vertical transmission of HBV.Maternal screening is the first step to prevent vertical transmission of HBV.Hepatitis B passive and active immunoprophylaxis at birth together with antiviral treatment of highly viraemic mothers are the key strategies for global elimination of HBV infection.Strategies are needed to promote implementation of birth-dose vaccination and hepatitis B immunoglobulins in low-and middle-income countries where the prevalence of the infection is at the highest. | Piero Veronese Icilio Dodi Susanna Esposito Giuseppe Indolfi | 2021 | World Journal of Gastroenterology2021，27，26： | 10 |
| 4 | Results, Outcome Predictors, and Complications after Stapled Transanal Rectal Resection for Obstructed Defecation显示文摘 | Giuseppe Gagliardi M.D. Mario Pescatori M.D. F.R.C.S. E.B.S.Q. Donato F. Altomare M.D. Gian Andrea Binda M.D. Corrado Bottini M.D. Giuseppe Dodi M.D. Vincenzino Filingeri M.D. Giovanni Milito M.D. Marcella Rinaldi M.D. Giovanni Romano M.D. Liana Spazzaf | 2008 | Diseases of the Colon & Rectum2008，，2： | 2 |
| 5 | Blood classical monocytes phenotype is not altered in primary non-small cell lung cancer显示文摘AIM: To evaluate the M1 and M2 monocyte phenotype in patients with non-small cell lung cancer(NSCLC) compared to controls. Also, to examine the expression of Th1 and Th2 cytokines in plasma of NSCLC vs controls. METHODS: Freshly prepared peripheral blood mononuclear cells samples were obtained from patients with NSCLC(lung adenocarcinoma and squamous cell lung carcinoma) and from non-cancer controls. Flow cytometry was performed to investigate M1 and M2 phenotypes in peripheral monocytes(classical monocytes CD14+, CD45+ and CD16-) using conventional surface markers. Th1 and Th2 cytokine production was alsoanalysed in the plasma using cytometric bead array technique. RESULTS: There were no significant difference in expression of M1(HLA-DR) and/or M2 markers(CD163 and CD36) markers on classical monocytes in patients with NSCLC compared to non-cancer controls. Expression of CD11 b, CD11 c, CD71 and CD44 was also shown to be similar in patients with NSCLC compared to noncancer controls. Th1 and Th2 cytokines [interleukin(IL)-1β, IL-2, IL-4, IL-5, IL-8, IL-10, IL-12(p70), tumor necrosis factor(TNF)-α, TNF-β, and interferon-γ] analysis revealed no significant difference between patients with NSCLC and non-cancer controls. CONCLUSION: This study shows no alteration in peripheral monocyte phenotype in circulating classical monocytes in patients with NSCLC compared to noncancer controls. No difference in Th1 and Th2 cytokine levels were noted in the plasma of these patients. | Saleh A Almatroodi Christine F Mc Donald Allison L Collins I an A Darby Dodie S Pouniotis | 2014 | World Journal of Clinical Oncology2014，5，5： | 2 |
| 6 | On cryptography with auxiliary input显示文摘 | Dodis Y Tauman Kalai Y Lovett S | 2009 | Proceedings of the 41st Annual ACM Symposium on Theory of Computing2009，，： | 1 |
| 7 | Direct evidence that leukemic cells present HLA-associated immunogenic peptides derived from the BCR-ABL b3a2 fusion protein 显示文摘 | Clark RE Dodi IA Hill SC | 2001 | Blood2001，98，10： | 1 |
| 8 | Fuzzy extractors: how to generate strong keys from biometrics and other noisy data 显示文摘 | Dodis Y | 2008 | SIAM Journal on Com- puting2008，38，1： | 1 |
| 9 | Public-key encryption schemes with auxiliary inputs显示文摘 | Dodis Y Goldwasser S Kalai Y T | 2010 | Theory of Cryptography2010，，5978： | 1 |
| 10 | Fuzzy Extractor: How to Generate Strong Keys from Biometrics and Other Noisy Data显示文摘 | Dodis Y Ostrovsky R Reyzin L | 2008 | SIAM Journal on Computing2008，38，1： | 1 |
| 11 | An overview of biomass energy utilization in Vojvodina 显示文摘 | Sinisa N Dodic Stevan D Popov Jelena M Dodie | 2010 | Renewable and Sustainable Energy Reviews2010，14，1： | 1 |
| 12 | Leakage-resilient public-key cryptography in the bounded-retrieval model显示文摘 | Alwen J Dodis Y Wichs D | 2009 | Advances in CryptologyCRYPTO2009，，5677： | 1 |
| 13 | Complications after stapled hemorrhoidectomy: can they be prevented?显示文摘 | B. Ravo A. Amato V. Bianco P. Boccasanta C. Bottini A. Carriero G. Milito G. Dodi D. Mascagni S. Orsini R. Pietroletti V. Ripetti G. B. Tagariello | 2002 | Techniques in Coloproctology2002，，2： | 1 |
| 14 | Public-key encryption in the bounded-retrieval model显示文摘 | Alwen J Dodis Y Naor M | 2010 | Advances in Cryptology-EUROCRYPT2010，，6110： | 1 |
| 15 | Cryptography against continuous memory attacks显示文摘 | Dodis Y Haralambiev K Lopez-Alt A | 2010 | Proceedings of the 51st Annual IEEE Symposium on Foundations of Computer Science2010，，： | 1 |
| 16 | Done Pezil improves cognieion and global fanction in Alxheimer's disease; a 15-weekdouble-blind,placebo-controlled studyp显示文摘 | Rogers SL Dody RS Mohs Rc | 1998 | Aroh Intern Med1998，158，9： | 1 |
| 17 | Fuzzy extractors: How to generate strong keys from biometrics and other noisy data显示文摘 | DODIS Y OSTROVSKY R REYZIN L | 2008 | SIAM Journal on Computing2008，38，1： | 1 |
| 18 | Direct evidence that leukemic cells present HLA-associated immunogenic peptides derived from the BCR-ABL b3a2 fusion protein显示文摘 | Clark RE Dodi A Hill SC | 2001 | Blood2001，98，： | 1 |
| 19 | Fuzzy extractors: how to generate strong keys from biometrics and other noisy data显示文摘 | Dodis Y Reyzin L Smith A | 2008 | SIAM Journal on Computing2008，38，1： | 1 |
| 20 | FuzzyExtractors: How to Generate Strong Keys from Biometrics and OtherNoisy Data显示文摘 | DODIS Y OSTROVSKY R REYZIN L | 2008 | SIMA Journal on Computing2008，38，1： | 1 |
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