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| 1 | Clinical diagnosis of bacterial vaginosis 显示文摘 | Simoes JA Discacciati MG Brolazo EM | 2006 | Int J Gynaecol Obstet2006，94，1： | 1 |
| 2 | Is bacterial vaginosis associated with squamous intraepithelial le- sion of the uterine cervix? 显示文摘 | Discacciati MG Simoes JA Lopes ES | 2006 | Diagn Cytopathol2006，34，5： | 1 |
| 3 | Presence of 20 % or more clue cells: an accurate criterion for the diagnosis of bacterial vaginosis in Papanicolaou cervical smears显示文摘 | Discacciati MG Simoes JA Amaral RG | 2006 | Diagn Cytopathol2006，34，4： | 1 |
| 4 | Coffee consumption and mortality from all causes, cardiovascular disease, and cancer: A dose-response recta-analysis 显示文摘 | Crippa A Discacciati A Larsson SC | 2014 | Am J Epidemiol2014，180，8： | 1 |
| 5 | MMP-9 expression increases according to the grade of squamous intraepithelial lesion in cervical smears显示文摘 | Matheus ER Zonta MA Discacciati MG | 2014 | Diagn Cytopathol2014，42，10： | 1 |
| 6 | Navier-Stokes/Darcy coupling:Modeling,analysis,and numerical approximation显示文摘 | Discacciati M Quarteroni A | | 0，，： | 1 |
| 7 | Coffee consumption and risk of localized, advanced and fatal prostate cancer: A population-based prospective study 显示文摘 | Discacciati A Orsini N Andersson SO | 2013 | Ann Oncol2013，24，7： | 1 |
| 8 | Clinical diagnosis of bacterial vaginosis 显示文摘 | Simoes JA Discacciati MG Brolazo EM | 2006 | Int J Gynaecol Obstet2006，94，1： | 1 |
| 9 | Re: Coffee consumption and risk of prostate cancer: An up-to-date meta-analysis显示文摘 | Discacciati A Orsini N | 2014 | Eur J Clin Nutr2014，68，3： | 1 |
| 10 | Microbiological characteristics and inflammatory cytokines associated with pre-term labor显示文摘 | Discacciati MG Simoes JA Silva MG | 2011 | Arch Gynecol Obstet2011，283，3： | 1 |
| 11 | Clinical diagnosis of Bacterial vaginosis 显示文摘 | Simoes JA Discacciati MG Brolazo EM | 2006 | Int J Gynaecol Obstet2006，94，1： | 1 |
| 12 | Microbiological characteristics and inflammatory cytokines associated with preteim labor 显示文摘 | DISCACCIATI M G SIMOES J A SILVA M G | 2011 | Arch Gynecol Obstet2011，283，3： | 1 |
| 13 | Erythema elcvatum di- utinum as a first clinical manifestation for diagnosing HIV irffeetion : case history显示文摘 | Rover PA Bittencourt C Discacciati MP | 2005 | Sao Paulo Med J2005，123，4： | 1 |
| 14 | Coffee consumptionand mortality from all causes, cardiovascular disease, and cancer: A dose-response meta-analysis 显示文摘 | Crippa A Discacciati A Larsson SC | 2014 | Am J Epidemiol2014，180，8： | 1 |
| 15 | Body mass index and incidence of localized and advanced prostate cancer-a dose-response meta-analysis of prospective studies显示文摘 | Discacciati A Orsini N Wolk A | 2012 | Ann Oncol2012，23，7： | 1 |
| 16 | HPV16 is related to the progression of cervical intraepithelial neoplasia grade 2:a case series显示文摘 | Loffredo D'Ottaviano M G Discacciati M G Andreoli M A | 2013 | Obstet Gynecol Int2013，2013，32： | 1 |
| 17 | MMP-9 Expres- sion Increases According to the Grade of Squamous Intraepithelial Lesion in Cervical Smears显示文摘 | Matheus ER Zonta MA Discacciati MG | 2014 | Diagn Cytopathol2014，42，10： | 1 |
| 18 | Presence of 20% or more clue ceils: an accurate criterion for the diagnosis of bacterial vaginosis in Papanicolaou cervical smears 显示文摘 | Discacciati MG Simnes JA Amaral RG | 2006 | Diagn Cytopathol2006，34，4： | 1 |
| 19 | Invasive cervical resorption:etiology,diagnosis,classification and treatment显示文摘 | Discacciati JA de Souza EL Costa SC | 2012 | J Contemp Dent Pract2012，13，5： | 1 |
| 20 | Risk factors associated with inflammatory bowel disease: A multicenter case-control study in Brazil显示文摘BACKGROUND The etiology of inflammatory bowel disease(IBD)is unknown,but it is believed to be multifactorial.The hygiene hypothesis proposes that better hygiene conditions would lead to less infectious disease during childhood and favor the development of immune-mediated diseases.AIM To test the hygiene hypothesis in IBD by assessing the environmental risk factors associated with IBD development in different regions of Brazil with diverse socioeconomic development indices.METHODS A multicenter case-control study was carried out with 548 Crohn’s disease(CD)and 492 ulcerative colitis(UC)outpatients and 416 healthy controls,from six IBD centers within different Brazilian states at diverse socioeconomic development stages.A semi-structured questionnaire with 87 socioeconomic and environmental questions was applied.Logistic regression model was created to assess the odds ratio(OR)with P value and 95%confidence intervals(CI).RESULTS Predictive variables for both diseases(CD and UC)were women[odd ratios(OR)=1.31;OR=1.69],low monthly family income(OR=1.78;OR=1.57),lower number of cohabitants(OR=1.70;OR=1.60),absence of vaccination(OR=3.11;OR=2.51),previous history of bowel infections(OR=1.78;OR=1.49),and family history of IBD(OR=5.26;OR=3.33).Associated risk factors for CD were age(18-39 years)(OR=1.73),higher educational level(OR=2.22),absence of infectious childhood diseases(OR=1.99).The UC predictive variables were living in an urban area(OR=1.62),inadequate living conditions(OR=1.48)and former smokers(OR=3.36).Appendectomy was a risk factor for CD(OR=1.58)with inverse association with UC(OR=4.79).Consumption of treated and untreated water was associated with risk of CD(OR=1.38)and UC(OR=1.53),respectively.CONCLUSION This is the first examining environmental exposures as risk factors for inflammatory bowel disease in Brazil.Most of the variables associated with disease risk support the role of the hygiene hypothesis in IBD development. | Valéria Cristina Loureiro Salgado Ronir Raggio Luiz Neio Lucio Fernandes Boéchat Isabella Sued Leao Bianca do Carmo Schorr JoséMiguel Luz Parente Daniela Calado Lima Eduardo Santos Silveira Júnior Genoile Oliveira Santana Silva Neogélia Pereira Almeida Andrea Vieira Maria Luiza Queiroz de Bueno Júlio Maria Chebli érika Ruback Bertges Luísa Martins da Costa Brugnara Columbano Junqueira Neto Stefania Burjack Gabriel Campbell Luana Letiza Discacciati Joao Paulo Silva Cézar Tiago Nunes Gilaad G Kaplan Cyrla Zaltman | 2020 | World Journal of Gastroenterology2020，26，25： | 1 |
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