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4篇 您的检索式:作者名="Dimitrios Dimitroulopoulos"
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1Pancreatic duct guidewire placement for biliary cannulation in a single-session therapeutic ERCP显示文摘AIM: To investigate the technical success and clinical complication rate of a cannulated pancreatic duct with guidewire for biliary access. METHODS: During a five-year study period, a total of 2843 patients were included in this retrospective analysis. Initial biliary cannulation method consisted of single-guidewire technique (SGT) for up to 5 attempts, followed by double-guidewire technique (DGT) when repeated unintentional pancreatic duct cannulation had taken place. Pre-cut papillotomy technique was reserved for when DGT had failed or no pancreatic duct cannulation had been previously achieved. Main outcome measurements were defined as biliary cannu-lation success and post-endoscopic retrograde cholangiopancreatography (ERCP) complication rate. RESULTS: SGT (92.3% success rate) was characterized by statistically significant enhanced patient outcome compared to either the DGT (43.8%, P < 0.001), pre-cut failed DGT (73%, P < 0.001) or pre-cut as first step method (80.6%, P = 0.002). Pre-cut as first step method offered a statistically significantly more favorable outcome compared to the DGT (P < 0.001). The incidence of post-ERCP pancreatitis did not differ in a statistically significant manner between either method (SGT: 5.3%, DGT: 6.1%, Pre-cut failed DGT: 7.9%, Pre-cut as first step: 7.5%) or with patients' gender. CONCLUSION: Although DGT success rate proved not to be superior to SGT or pre-cut papillotomy, it is considered highly satisfactory in terms of safety in order to avoid the risk of a pre-cut when biliary therapy is necessary in difficult-to-cannulate cases.Dimitrios Xinopoulos Stefanos P Bassioukas Dimitrios Kypreos Dimitrios Korkolis Andreas Scorilas Konstantinos Mavridis Dimitrios Dimitroulopoulos Emmanouil Paraskevas 2011World Journal of Gastroenterology2011,17,15:8
2Do Papillary Manipulations with a Guidewire Increase the Incidence of Post-ERCP Pancreatitis? Lessons Learned from 1858 Consecutive Therapeutic Endoscopic Retrograde Cholangiopancreatographies (ERCPs) from a Single Institution显示文摘Dimitrios Xinopoulos Stefanos P. Bassioukas Dimitrios Kypreos Dimitrios Dimitroulopoulos Dimitris P. Korkolis Klisthenis Tsamakidis Stamatia Patsavela Emmanuil Paraskevas 2009Gastrointestinal Endoscopy2009,,5:1
3The role of sandostatin LAR in treating patients with advanced hepatocellular cancer显示文摘Dimitrios Dimitroulopoulos Dimitrios Xinopoulos Klisthenis Tsamakidis 2002Hepato-gastroenterology2002,49,:1
4Herpes simplex virus type 1 in peptic ulcer disease: An inverse association with Helicobacter pylori显示文摘AIM: To assess the frequency of herpes simplex virus type Ⅰ in upper gastrointestinal tract ulcers and normal mucosa with the modern and better assays and also with a larger number of well characterized patients and controls and its relationship to Helicobacter pylori(H pylori).METHODS: Biopsy specimens from 90 patients (34 with gastric ulcer of the prepyloric area and 56 with duodenal ulcer) were evaluated. Biopsies from 50 patients with endoscopically healthy mucosa were considered as the control group. The method used to identify herpes simplex virus-1 (HSV-1) was polymerase chain reaction.H pylori was detected by the CLO-test and by histological method.RESULTS: Herpes simplex virus-1 was detected in 28 of 90 patients with peptic ulcer (31%) [11 of 34 patients with gastric ulcer (32.4%) and 17 of 56 with duodenal ulcer (30.4%)] exclusively close to the ulcerous lesion.All control group samples were negative for HSV-1.The likelihood of H pylori negativity among peptic ulcer patients was significantly higher in HSV-1 positive cases than in HSV-1 negative cases (P = 0.009). Gastric ulcer patients with HSV-1 positivity were Strongly associated with an increased possibility of Helicobacter pylori negativity compared to duodenal ulcer patients (P= 0.010).CONCLUSION: HSV-1 is frequent in upper gastrointestinal tract ulcers but not in normal gastric and duodenal mucosa. There is an inverse association between HSV-1 and H pylori infection.Klisthenis Tsamakidis Efstathia Panotopoulou Dimitrios Dimitroulopoulos Dimitrios Xinopoulos Maria Christodoulou Alexandra Papadokostopoulou Ioannis Karagiannis Elias Kouroumalis Emmanuel Paraskevas 2005World Journal of Gastroenterology2005,11,42:0
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