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| 1 | Colonoscopic yield of colorectal neoplasia in daily clinical practice显示文摘AIM:To assess the prevalence and location of ad-vanced neoplasia in patients undergoing colonoscopy,and to compare the yield per indication.METHODS:In a multicenter colonoscopy survey (n = 18 hospitals) in the Amsterdam area (Northern Holland),data of all colonoscopies performed during a three month period in 2005 were analyzed. The location and the histological features of all colonic neoplasia were recorded. The prevalence and the distribution ofadvanced colorectal neoplasia and differences in yield between indication clusters were evaluated. Advanced neoplasm was defi ned as adenoma > 10 mm in size,with > 25% villous features or with high-grade dyspla-sia or cancer.RESULTS:A total of 4623 eligible patients underwent a total colonoscopy. The prevalence of advanced neo-plasia was 13%,with 281 (6%) adenocarcinomas and 342 (7%) advanced adenomas. Sixty-seven percent and 33% of advanced neoplasia were located in the distal and proximal colon,respectively. Of all patients with right-sided advanced neoplasia (n = 228),51% had a normal distal colon,whereas 27% had a syn-chronous distal adenoma. Ten percent of all colono-scopies were performed in asymptomatic patients,7% of whom had advanced neoplasia. In the respective procedure indication clusters,the prevalence of right-sided advanced neoplasia ranged from 11%-57%. CONCLUSION:One out of every 7-8 colonoscopies yielded an advanced colorectal neoplasm. Colonoscopy is warranted for the evaluation of both symptomatic and asymptomatic patients. | Jochim S Terhaar sive Droste Mike E Craanen Rene WM van der Hulst Joep F Bartelsman Dick P Bezemer Kim R Cappendijk Gerrit A Meijer Linde M Morsink Pleun Snel Hans ARE Tuynman Roy LJ van Wanrooy Eric IC Wesdorp Chris JJ Mulder | 2009 | World Journal of Gastroenterology2009，15，9： | 6 |
| 2 | Origin and therapy for hypertriglyceridaemia in type 2 diabetes显示文摘Hypertriglyceridaemia(HTG) is a risk factor for cardiovascular disease(CVD) in type 2 diabetes and is caused by the interaction of genes and non-genetic factors, specifically poor glycaemic control and obesity. In spite of statin treatment, residual risk of CVD remains high in type 2 diabetes, and this may relate to HTG and atherogenic dyslipidemia. Treatment of HTG emphasises correcting secondary factors and adverse lifestyles, in particular, diet and exercise. Pharmacotherapy is also required in most type 2 diabetic patients. Statins are the first-line therapy to achieve recommended therapeutic targets of plasma low-density lipoprotein cholesterol and non-high-density lipoprotein cholesterol. Fibrates, ezetimibe and n-3 fatty acids are adjunctive treatment options for residual and persistent HTG. Evidence for the use of niacin has been challenged by non-significant CVD outcomes in two recent large clinical trials. Further investigation is required to clarify the use of incretin-based therapies for HTG in type 2 diabetes. Extreme HTG, with risk of pancreatitis, may require insulin infusion therapy or apheresis.New therapies targeting HTG in diabetes need to be tested in clinical endpoint trials. The purpose of this review is to examine the current evidence and provide practical guidance on the management of HTG in type 2 diabetes. | Jing Pang Dick C Chan Gerald F Watts | 2014 | World Journal of Diabetes2014，5，2： | 2 |
| 3 | Innammation after sclemcomeal versus clear comeal tunnel phacoemulsification显示文摘 | Dick HB Schwenn O Krummenauer F | 2000 | Ophthalmology2000，107，： | 1 |
| 4 | Optimizing the selection of bridging particles for reservoir drilling fluids 显示文摘 | Dick M A Heinz T J Svoboda C F | 2000 | SPE 587932000，，： | 1 |
| 5 | Inflammation after seleroeorneal versus clear corneal tunnel phacoemulsifieation显示文摘 | Dick H B Schwenn O Krummenauer F | 2000 | ophthalmol omgy2000，107，3： | 1 |
| 6 | A simple reversed phase high-performance liquid chromatography method polysorbate 80 quantitation in monoclonal antibody drug products显示文摘 | ADAMO M DICK L W Jr QIU D F | 2010 | J Chromatogr B Analyt Technol Biomed Life Sci2010，878，21： | 1 |
| 7 | Surgical or endo- vascular revascularization in patients with critical limb ischemia: influence of diabetes mellitus on clincical out- come显示文摘 | Dick F Diebm N Galimanis A | 2007 | J Vasc Surg2007，45，4： | 1 |
| 8 | A new device for internal fixation of thoraclumbar and Lumbar spine fractures: The''fixatear interne''显示文摘 | Dick W Kluger P Magerl F | 1985 | Paraplegia1985，23，： | 1 |
| 9 | A new device for internal fixation of thoracolumbar and Lumbar spine fractures:The 'fixateur interne”显示文摘 | Dick W Kliuqer P Magerl F | 1985 | Paraplegia1985，23，： | 1 |
| 10 | Isolation of Lactococcus lactis nonsense suppressors and construction of a food-grade cloning vector显示文摘 | Dickely F Nilsson D Hansen E B | 1995 | Mol Microbiol1995，15，5： | 1 |
| 11 | Digital Receivers and Transmitters Using Polyphase Fiker Banks for Wireless Communications 显示文摘 | Harris F J Dick C and Rice M | 2003 | IEEE Transactions on Microwave Theory and Techniques2003，51，4： | 1 |
| 12 | Digital receivers and transmitters using polyphase filter banks for wireless communications 显示文摘 | Harris F J Dick C Rice M | 2003 | [EEE Transactions on Microwave Theory and Techniques2003，51，4： | 1 |
| 13 | Digital receivers and transmitters using Polyphase filter banks for wireless communication 显示文摘 | Harris F Dick C Rice M | 2003 | IEEE Transactions on MicrowaveTheory and Techniques2003，51，4： | 1 |
| 14 | A new device for internal fixation of thoracolumbar and lumbar spine fractures:the'fixateur interne'显示文摘 | Dick W Kluger P Magerl F | 1985 | Paraplegia1985，23，4： | 1 |
| 15 | Objective and subjective evaluation of photie phenomena after monofocal and multifocal intraocular lens i mplantation显示文摘 | Dick HB Krummenauer F Schwenn O Krist R Pfeiffer N | 1999 | Ophthalmology1999，106，10： | 1 |
| 16 | A new device internal fixation of thoracolumbar and lumbar spine fracture: the fixateur interne显示文摘 | Dick W Kluger P Mager F | 1985 | Paraplegia1985，23，： | 1 |
| 17 | Soil microbial dynamics: short- and long- term effects of inorganic and organic nitrogen显示文摘 | Fauci M F Dick R P | 1994 | Soil Science Society of American Journal1994，58，3： | 1 |
| 18 | Surgical or endovascular revasculation in patients with critical limb ischemia:influence of diabetes mellitus on clinical outcome显示文摘 | Dick F Diehm N Galimailis A | 2007 | J Vasc Sur2007，45，4： | 1 |
| 19 | The impact of educational interven- tions on primary health care workers' knowledge of occupational ex- posure to blood or body fluids显示文摘 | Krishnan P Dick F Murphy E | 2007 | Occup Med(Lond)2007，57，2： | 1 |
| 20 | Foldable Artiflex phakic intraocular lens for the correction of myopia: two-year follow-up results of a prospective European multicenter study 显示文摘 | Dick HB Budo C Malecaze F Guell JL Marinho AA Nuijts RM | 2009 | Ophthalmology2009，116，4： | 1 |
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