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| 1 | Giant cavernous liver hemangiomas: is it the time to change the size categories?显示文摘BACKGROUND: Four different sizes(4, 5, 8 and 10 cm in diameter) can be found in the literature to categorize a liver hemangioma as giant. The present review aims to clarify the appropriateness of the size category 'giant' for liver hemangioma.DATA SOURCES: We reviewed the reports on the categorization of hemangioma published between 1970 and 2014. The number of hemangiomas, size criteria, mean and range of hemangioma sizes, and number of asymptomatic and symptomatic patients were investigated in patients aged over 18 years. Liver hemangiomas were divided into four groups: <5.0 cm, 5.0-9.9 cm, 10.0-14.9 cm and ≥15.0 cm in diameter. Inclusion criteria were noted in 34 articles involving 1972(43.0%) hemangiomas(>4.0 cm).RESULTS: The patients were divided into the following groups: 154 patients(30.0%) with hemangiomas less than 5.0 cm in diameter(small), 182(35.5%) between 5.0 cm and 9.9 cm(large), 75(14.6%) between 10.0 and 14.9 cm(giant), and 102(19.9%) more than 15.0 cm(enormous). There were 786(39.9%) asymptomatic patients and 791(40.1%) symptomatic patients. Indications for surgery related to symptoms were reported in only 75(3.8%) patients. Operations including 137 non-anatomical resection(12.9%) and 469 enucleation(44.1%) were unclearly related to size and symptoms.CONCLUSIONS: The term 'giant' seems to be justified for liver hemangiomas with a diameter of 10 cm. Hemangiomas categorized as 'giant' are not indicated for surgery. Surgery should be performed only when other symptoms are apparent. | isidoro di carlo renol koshy saif al mudares annalisa ardiri gaetano bertino adriana toro | 2016 | Hepatobiliary & Pancreatic Diseases International2016，15，1： | 22 |
| 2 | Chronic hepatitis C:This and the new era of treatment显示文摘Over the last years it has started a real revolution in the treatment of chronic hepatitis C. This occurred for the availability of direct-acting antiviral agents that allow to reach sustained virologic response in approximately 90% of cases. In the near future further progress will be achieved with the use of pan-genotypic drugs with high efficacy but without side effects. | Gaetano Bertino Annalisa Ardiri Maria Proiti Giuseppe Rigano Evelise Frazzetto Shirin Demma MariaIrene Ruggeri Laura Scuderi Giulia Malaguarnera Nicoletta Bertino Venerando Rapisarda Isidoro Di Carlo Adriana Toro Federico Salomone Mariano Malaguarnera Emanuele Bertino Michele Malaguarnera | 2016 | World Journal of Hepatology2016，8，2： | 10 |
| 3 | Hepatocellular carcinoma and the risk of occupational exposure显示文摘Hepatocellular carcinoma(HCC)is the most common type of liver cancer.The main risk factors for HCC are alcoholism,hepatitis B virus,hepatitis C virus,nonalcoholic steatohepatitis,obesity,type 2 diabetes,cirrhosis,aflatoxin,hemochromatosis,Wilson’s disease and hemophilia.Occupational exposure to chemicals is another risk factor for HCC.Often the relationship between occupational risk and HCC is unclear and the reports are fragmented and inconsistent.This review aims to summarize the current knowledge regarding the association of infective and non-infective occupational risk exposure and HCC in order to encourage further research and draw attention to this global occupational public health problem. | Venerando Rapisarda Carla Loreto Michele Malaguarnera Annalisa Ardiri Maria Proiti Giuseppe Rigano Evelise Frazzetto Maria Irene Ruggeri Giulia Malaguarnera Nicoletta Bertino Mariano Malaguarnera Vito Emanuele Catania Isidoro Di Carlo Adriana Toro Emanuele Bertino Dario Mangano Gaetano Bertino | 2016 | World Journal of Hepatology2016，8，13： | 5 |
| 4 | Systemic therapies in hepatocellular carcinoma: present and future显示文摘 | Gaetano Bertino Isidoro Di Carlo Annalisa Ardiri Giuseppe Stefano Calvagno Shirin Demma Giulia Malaguarnera Nicoletta Bertino Mariano Malaguarnera Adriana Toro Michele Malaguarnera | 2013 | Future Oncol2013，，10： | 3 |
| 5 | Isoscalar-vector interaction and its influence on the hadron-quark phase transition显示文摘The hadron-quark phase transition is studied with the newly constructed Hadron-Poyakov-Nambu- Jona-Lasinio(PNJL) model.Particularly,in the description of quark matter,we include the isoscalar-vector interaction.With the constraints of neutron star observations,our calculation shows the isoscalar-vector interaction between quarks is indispensable if massive hybrids star exist in the universe.Its strength determines the onset density of quark matter,and the mass-radius relations of hybrid stars.Also,as a connection with heavy-ion-collision experiments,we discuss the strength of isoscalar-vector interaction and its effect on the signals of hadron-quark phase transition in heavy-ion collisions,such as NICA at JINR-Dubna and FAIR at GSI-Darmstadt. | SHAO Guoyun COLONNA Maria DI TORO Massimo LIU Yuxin LIU Bo | 2013 | Nuclear Science and Techniques2013，24，5： | 2 |
| 6 | Reversible and resistant components of PCB adsorption-desorption: Isotherms 显示文摘 | Horzempa L M | 1982 | Environ Sci Technol1982，16，9： | 1 |
| 7 | Toxicity of cadmium in sediments: the role of acid volatile sulfide 显示文摘 | Di Toro D M Mahony J D Hansen D J | 1990 | Environmental Toxicology and Chemistry1990，9，12： | 1 |
| 8 | Toxicity of cadmium in sediments: the role of acid volatile sulfide 显示文摘 | DI TORO D M MAHONY J D HANSEN D J | 1990 | Environmental Toxicology and Chemistry1990，9，12： | 1 |
| 9 | A Dynamic Model of Phytoplankton Population In the sacramento San Joaquin Delta显示文摘 | Di toro D M O'Connor D J Thomann T V | 1971 | Advances in Chemistry American Chemical Society1971，106，： | 1 |
| 10 | AVS predicts the actte toxicity of Cd and Ni in sediments 显示文摘 | DI TORO D M MAHONY J D HANSEN D L | 1992 | Environmental Science & Technology1992，26，1： | 1 |
| 11 | Deferoxamine antioxidant activity on cerebellar granule cells T-irradiated in vitro显示文摘 | Guelman LR Pagotto RM Di Toro CG | 2004 | Neurotoxicol Teratol2004，26，3： | 1 |
| 12 | External jugular vein cut down approach, as a useful alternative, supports the ehoice of the eephalie vein for totally implantable access device placement 显示文摘 | Di Carlo I Barbagallo F Toro A | 2005 | Ann Surg Oncol2005，12，7： | 1 |
| 13 | Hepatic resections using a water-cooled, high-density, monopolar device: a new technology for safer surgery显示文摘 | Di Carlo I Barbagallo F Toro A | 2004 | d Gastwintest Surg2004，8，5： | 1 |
| 14 | Predicting sediment metal toxicity using a sediment biotic ligand model: Methodology and initial application 显示文摘 | DI TORO D MCGRATH J A HANSEN D J | 2005 | Environmental Toxi- cology and Chemistry2005，24，10： | 1 |
| 15 | Toxicity of cadmium in sediments:the role of acid volatile sulfide显示文摘 | Di Toro D M Mahony J D Hansen D J | 1990 | Environ Toxicol Chem1990，9，： | 1 |
| 16 | Physico - chemical model of toxic substances in the Great Lakes 显示文摘 | THOMANN R V DI TORO D M | 1983 | Journal of Great Lakes Research1983，9，4： | 1 |
| 17 | Toxicity of cadmium in sediments: The role of acid volatile sulfide 显示文摘 | Di Toro D M Mahony J D M B Mayr S M Redmond Hansen D J Scott K J Hicks M S | 1990 | Environmental Toxicology and Chemistry1990，26，1： | 1 |
| 18 | Toxicity of cadmium in sediments:The role of acid volatile sulfide显示文摘 | DI TORO D M | 1990 | Environmental Toxicology and Chemistry1990，，9： | 1 |
| 19 | Toxicity of cadmium in sediments : The role of acid 'mlati|e sulfide 显示文摘 | DI TORO D M MAHONY J D HANSEN D J | 1990 | Environmental Toxicology and Chemistry1990，9，： | 1 |
| 20 | Toxicity of cadmium in sediments:The role of acid volatile sulfide显示文摘 | DI TORO D M MAHONY J D HANSEN D J | 1990 | Environmental Toxicology and Chemistry1990，9，： | 1 |
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