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| 1 | Outcomes of submucosal(T1b) esophageal adenocarcinomas removed by endoscopic mucosal resection显示文摘AIM To investigate the outcomes and recurrences of p T1 b esophageal adenocarcinoma(EAC) following endoscopic mucosal resection(EMR) and associated treatments.METHODS Patients undergoing EMR with pathologically confirmed T1 b EAC at two academic referral centers were retrospectively identified.Patients were divided into 4 groups based on treatment following EMR:Endoscopic therapy alone(group A),endoscopic therapy with either chemotherapy,radiation or both(group B),surgicalresection(group C) or no further treatment/lost to follow-up(<12 mo)(group D).Pathology specimens were reviewed by a central pathologist.Follow-up data was obtained from the academic centers,primary care physicians and/or referring physicians.Univariate analysis was performed to identify factors predicting recurrence of EAC.RESULTS Fifty-three patients with T1 b EAC underwent EMR,of which 32(60%) had adequate follow-up ≥ 12 mo(median 34 mo,range 12-103).There were 16 patients in group A,9 in group B,7 in group C and 21 in group D.Median follow-up in groups A to C was 34 mo(range 12-103).Recurrent EAC developed overall in 9 patients(28%) including 6(38%) in group A(median:21 mo,range:6-73),1(11%) in group B(median:30 mo,range:30-30) and 2(29%) in group C(median 21 mo,range:7-35.Six of 9 recurrences were local;of the 6 recurrences,5 were treated with endoscopy alone.No predictors of recurrence of EAC were identified.CONCLUSION Endoscopic therapy of T1 b EAC may be a reasonable strategy for a subset of patients including those either refusing or medically unfit for esophagectomy. | Darren D Ballard Neel Choksi Jingmei Lin Eun-Young Choi B Joseph Elmunzer Henry Appelman Douglas K Rex Hala Fatima William Kessler John M DeWitt | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，20： | 2 |
| 2 | Human disease modeling with induced pluripotent stem cells显示文摘 | Alan Trounson Kelly A Shepard Natalie D DeWitt | 2012 | Current Opinion in Genetics & Development2012，，5： | 2 |
| 3 | Duplication record elimination in large data files显示文摘 | Bitton D Dewitt D J | 1983 | ACM Trans on Database Systems1983，8，2： | 1 |
| 4 | Inferring temperature from optical radiation measurement显示文摘 | Dewitt D P | 1986 | Opt Eng1986，25，4： | 1 |
| 5 | Parallel database systems:the future of high performance database processing显示文摘 | Dewitt D J Gray J | 1992 | Communication of ACM1992，36，6： | 1 |
| 6 | Data placement in shared-nothing parallel database systems显示文摘 | M Mehta D J DeWitt | 1997 | VLDB Journal1997，6，1： | 1 |
| 7 | Tetra thymosinbeta is required for actin dynamics in Caenorhabditis elegans and acts via functionally dif- ferent actin-binding repeats显示文摘 | Van Troys M Ono K Dewitte D | 2004 | Mol Biol Cell2004，15，10： | 1 |
| 8 | Cytotoxieity, antioxi- dant and antiinflammatory activities of curcumins I -III from Cur- cumalonga 显示文摘 | Ramsewak R S DeWitt D L Nair M G | 2000 | Phytomedicine2000，7，4： | 1 |
| 9 | Characterization of inducible cyclooxygenase in rat brain 显示文摘 | Breder CD Dewitt D Kraig RP | 1995 | J Comp Neurol1995，355，： | 1 |
| 10 | Multiprocessor Hash-Based Join algorithms显示文摘 | DeWitt D J Gerber R | 1985 | Proceedings of International Conference on Very Large Data Bases1985，11，1： | 1 |
| 11 | MapReduce and parallel DBMSs: friends or foes 显示文摘 | Stonebraker M Abadi D DeWitt D J | 2010 | Communications of the ACM2010，53，1： | 1 |
| 12 | Inferring temperature from optical radiation measuremerit显示文摘 | Dewitt D P | 1986 | Opt Eng1986，25，4： | 1 |
| 13 | Application of the bland-altman plot for Interpretation of method comparison studies:a critical Investigation of its practice显示文摘 | Dewitte K Fierens C Stockl D | | 0，，05： | 1 |
| 14 | Cytotoxicity, antioxidant and anti-inflammatory activities of curcumins Ⅰ - Ⅲ from Curcuma longa 显示文摘 | Ramsewak R S DeWitt D L Nair M G | 2000 | Phytomedicine2000，7，4： | 1 |
| 15 | Insulin secretion and cyclo0xygenase enzyme inhibition by cabernet sauvignon grape skin compounds 显示文摘 | Zhang Y Jayaprakasam B Seeram NP Olson LK DeWitt D Nair MG | 2004 | J Agric Food Chem2004，52，2： | 1 |
| 16 | Application of the Bland-Altman plot for interpretation of method comparison studies:a critical investigation of its practice显示文摘 | Dewitte K Fierens C Stockl D | 2002 | ClinChem2002，48，5： | 1 |
| 17 | Duplicate record elimination in large data files显示文摘 | Bitton D DeWitt D J | 1983 | ACM Transactions on Database Systems1983，8，2： | 1 |
| 18 | Cytotoxieity, antiox- idant and anti-inflammatory activities of curcumins I-m from Curcu ma longa 显示文摘 | Ramsewak R S DeWitt D L Nair M G | 2000 | Phytomedicine2000，7，4： | 1 |
| 19 | Regulation of the hu- man P450scc gene by steroidogenic factor 1 is medi- ated by CBP/p300显示文摘 | Monte D DeWitte F Hum DW | 1998 | J Biol Chem1998，273，： | 1 |
| 20 | On supporting containment queries in relational database management systems显示文摘 | ZHANG CHUN NAUGHTON J DEWITT D | 2001 | ACM SIGMOD Record2001，30，2： | 1 |
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