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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Primary hepatic carcinosarcoma显示文摘BACKGROUND:Primary hepatic carcinosarcoma is a rare malignant tumor containing an intimate mixture of carci- nomatous and sarcomatous elements.Reports on risk factors, epidemiology,and pathogenesis of the tumor as well as the experience in its treatment are limited. METHOD:We present a case of primary carcinosarcoma of the liver in a 69-year-old man who complained of right hypochondrial pain and weight loss for two months. RESULTS:Magnetic resonance imaging revealed a 14×12 cm mass in segments 7-8 and 4 of the liver with vena hepatica invasion.An ultrasonography-guided biopsy showed osteoid tissue without osteoblastic rimming.Vascular structures accompanied the osteoid tissue.The patient underwent surgery after a diagnosis of hemangioma.Intraoperative frozen sections revealed a carcinosarcoma associated with an osteosarcoma and cholangiocellular carcinoma components. CONCLUSIONS:Preoperative diagnosis of this rare primary hepatic malignant tumor may be difficult by biopsy owing to intratumoral heterogeneity.Highly mature areas of the osteosarcomatous component may lead to misdiagnosis of metaplastic bone tissue.Clinicopathologic features of this rare entity are discussed. | Mehmet elikbilek Kemal Deniz Edip Torun Tarιk Artιs Ersin zaslan kkes brahim Karahan Tahir Ercan Patιroglu mer zbakιr | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，1： | 2 |
| 3 | Effects of inlet flow field conditions on the performance of centrifugal compressor diffusers:straight channel diffuser显示文摘 | Deniz S Greitzer E M Cumpsty N A | 2000 | ASME Journal of Turbomachinery2000，122，1： | 1 |
| 4 | Decreased cytokine expression in peripheral blood leukocytes of patients with severe sepsis 显示文摘 | Cabioglu N Bilgic S Deniz G | 2002 | Arch Surg2002，137，9： | 1 |
| 5 | Some of the properties of particle- board made from Panlownia 显示文摘 | Kalaycioglu H Deniz I Hiziroglu S | 2005 | Journal of Wood Science2005，51，： | 1 |
| 6 | Analytic view to concordance be- tween electrocochleography and caloric test in Meniere's disease显示文摘 | Bulent S Serdar K Deniz S | 2008 | Eur Arch Otorhinolaryngol2008，265，10： | 1 |
| 7 | Risk factors for posterior ventricular rupture after mitral valve replacement : results of 2560 patients显示文摘 | Deniz H Sokullu 0 Sanioglu S | 2008 | Eur J Cardiothorac Surg2008，34，4： | 1 |
| 8 | Evaluation of metal concentration and antioxidant activity ofthree edible mushrooms from Mugla,Turkey 显示文摘 | Cengiz S Bektas T Deniz K S | 2010 | Food and Chemical Toxicology2010，48，5： | 1 |
| 9 | Substituent effects on the photochromic of bichromophoric oxazines显示文摘 | Deniz E Tomasulo M Sortino S | | 0，，19： | 1 |
| 10 | Compressive hyperextension injury of C2-C3 managed with anterior plate fixation: case report 显示文摘 | Deniz FE Caeli S Zileli M | 2007 | Turk Neurosurg2007，17，2： | 1 |
| 11 | Expression of PCNA and bcl-2 in basaloid squamous cell carcinoma of the la~nx: a controlled study显示文摘 | Deniz K Yuce l Cagli S | 2008 | Ear Nose Throat J2008，87，8： | 1 |
| 12 | Decreased cytokine expression in peripheral blood leukocytes of patients with severe sepsis显示文摘 | Cabioglu N Bilgic S Deniz G | 2002 | Arch Surg2002，137，9： | 1 |
| 13 | Temporal and spatial patterns of precipitation variability for annual,wet,and dry seasons inTurkey显示文摘 | Unal Y S Deniz A Toros H | 2012 | International Journal of Climatology2012，32，3： | 1 |
| 14 | Expression of PCNA and bcl-2 in basaloid squamous cell carcinoma of the larynx: a controlled study 显示文摘 | Deniz K Yuce I Caoli S | 2008 | Ear Nose Throat J2008，87，8： | 1 |
| 15 | Compressive hyperextension in- jury of C2- 3 managed with anterior plate fixation: case re- port显示文摘 | Deniz FE Cagli S Zileli M | 2007 | Turkish Neurosurgery2007，17，2： | 1 |
| 16 | Effects of nutritional supple- mentation combined with conventional pulmonary rehabilitation in muscle-wasted chronic obstructive pulmonary disease: a prospec- tive, randomized and controlled study 显示文摘 | Gurgun A Deniz S Argin M | 2013 | Respirology2013，18，3： | 1 |
| 17 | Unregistered subtracted CT angiography for the visualization of intracranial arteries at or near the skull base: preliminary experience 显示文摘 | Sarikaya B Sarikaya S Deniz FE | 2007 | Diagn Interv Radiol2007，13，3： | 1 |
| 18 | Risk factors for posterior ventricular rupture after mitral valve replacement: results of 2560 patients 显示文摘 | Deniz H Sokullu O Sanioglu S | 2008 | Eur J Cardiothorac Surg2008，34，4： | 1 |
| 19 | Generalized epileptic seizure in an adolescent idiopathic scoliosis (AIS) patient with syringomyelia after deformity correction surgery显示文摘 | Gultekin S?tk? Cecen Deniz Gulabi Ismail Oltulu Tolga Onay | 2013 | International Journal of Surgery Case Reports2013，，8： | 1 |
| 20 | The effects of electromagnetic fields on the ultrastructure of heart显示文摘 | Soker S Sert C Deniz M | 2011 | Int J Morphol2011，29，3： | 1 |
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