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| 1 | Pain sensation in pancreatic diseases is not uniform: The different facets of pancreatic pain显示文摘AIM: To systematically characterize specific pain patterns in the most frequent pancreatic diseases.METHODS: Pain in patients with chronic pancreatitis(n = 314), pancreatic cancer(n = 469), and other pancreatic tumors(n = 249) including mucinous(n = 20) and serous cystadenoma(n = 31), invasive(n = 37) and non-invasive intraductal papillary mucinous neoplasia(IPMN; n = 48), low stage(n = 18) and high stage neuroendocrine neoplasia(n = 44), and ampullary cancer(n = 51) was registered and correlated with clinicopathological data. Survival times were estimated by the Kaplan-Meier method. Patients alive at the follow-up time were censored. Survival curves were compared statistically using the log-rank test.RESULTS: Forty-nine point one percent of pancreatic cancer patients revealed no pain, whereas in chronic pancreatitis only 18.3% were pain free. In contrary, moderate/severe pain was registered in 15.1% in pancreatic cancer patients that was increased in chronic pancreatitis with up to 34.2%. Serous cystadenoma was asymptomatic in most cases(58.1%), whereas 78.9% of all mucinous cystadenoma patients suffered pain. In neuroendocrine neoplasia pain was not a key clinical symptom since 64% of low stage neuroendocrine neoplasia and 59% of high stage neuroendocrine neoplasia patients were pain free. Cancer localization in the pancreatic body and patients with malignant pancreatic neoplasms were associated with more severe pain. Tumor grading and stage did not show any impact on pain. Only in pancreatic cancer, pain was directly associated with impaired survival.CONCLUSION: Pancreatic pain depicts different patterns of abdominal pain sensation according to the respective pancreatic disorder and does not allow a unification of the term pancreatic pain. | Jan G D'Haese Mark Hartel Ihsan Ekin Demir Ulf Hinz Frank Bergmann Markus W Büchler Helmut Friess Güralp O Ceyhan | 2014 | World Journal of Gastroenterology2014，20，27： | 8 |
| 2 | Effects of TiO2 on the mechanical properties of the Al2O3 - TiO2 plasma sprayed coating显示文摘 | Yilmaza R Kurtb A O Demir A | 2007 | Journal of the European Ceramic Society2007，27，23： | 1 |
| 3 | Effect of right ventricular pacing lead on left ventricular dyssynchrony in patients receiving cardiac resynchronization therapy显示文摘 | Sade LE Demir O Atar I | 2009 | Am J Cardiol2009，103，： | 1 |
| 4 | Assessment of urban air quality in Istanbul using fuzzy synthetic evaluation显示文摘 | Galeda O E Demir I Halil H | | 0，，： | 1 |
| 5 | Clinical results of the liquidbased cervical cytology tool,Liqui-PREP,in comparison with conventional smears for detection of squamous cell abnormalities显示文摘 | Canda MT Demir N Sezer O | 2009 | Asian Pac J Cancer Prev2009，10，3： | 1 |
| 6 | Effect of mechanical dyssynchrony and cardiac resynchronization therapy on left ventricular rotational mechanics显示文摘 | SADE L E DEMIR O ATAR I | 2008 | Am J Cardiol2008，101，： | 1 |
| 7 | Prevalence of erectiledysfunction in patients with metabolic syndrome显示文摘 | Demir T Demir O Kefi A | 2006 | Int Jurol2006，13，4： | 1 |
| 8 | Assessment of urban air quality in Istanbul using fuzzy synthetic evaluation显示文摘 | O E Guleda I Demir H Halil | 2004 | Atmospheric Environment2004，38，23： | 1 |
| 9 | Morphology of the lumbar spinal canal in normal adult turks 显示文摘 | Tacar O Demirant A Nas K | 2003 | Yonsei Med J2003，44，4： | 1 |
| 10 | Clinical resu]Is of the liquid based cervical cytology tool, Liqui-PREP, in comparison with conventional smears for detection of squamous cell abnormalities 显示文摘 | Canda MT Demir N Sezer O | 2009 | Asian Pae J Cancer Prev2009，10，3： | 1 |
| 11 | Effects of TiO2 on the mechanical properties of the AlzO3-TiO2 plasma sprayed coating 显示文摘 | Yilmaz R Kurt A O Demir A | 2007 | Journal of the European Ceramic Society2007，27，23： | 1 |
| 12 | On Some Maps with P and Q Properties in Non-Normal Cone Metric Spcaces显示文摘 | DEMIRER H (O)ZT(U)RK M BASARIR M | | 0，，08： | 1 |
| 13 | Amniotic fluid angiogenin levels are decreased in pregnancies with fetal trisomy 21 显示文摘 | Demir A Guclu S Bige O | 2011 | Prenat Diagn2011，31，11： | 1 |
| 14 | A Hierarchical Clustering and Routing Procedure for Large Scale Disaster Relief Logistics Planning显示文摘 | Ozdamar L Demir O | 2012 | Transportation Research Part E:Logistics and Transportation Review2012，48，3： | 1 |
| 15 | Decreased prohepcidin levels in patients with HBV-related liver disease:relation with ferritin levels显示文摘 | Yonal O Akyuz F Demir K | 2010 | Dig Dis Sci2010，55，12： | 1 |
| 16 | lntramyocardial hematoma with epicardial rupture following percutaneous coronary intervention 显示文摘 | Ertan C Ozeke O Demir AD | 2013 | J Clin Uhrasound2013，41，2： | 1 |
| 17 | Fractalkine/CX3CR1: why a single chemokine-receptor duo bears a major and unique therapeutic potential显示文摘 | Jan G D’Haese Ihsan Ekin Demir Helmut Friess Güralp O Ceyhan | 2010 | Expert Opinion on Therapeutic Targets2010，，2： | 1 |
| 18 | Collaterals that regressed after angioplasty can be recruited to protect the left ventricle in case of an acute occlusion显示文摘 | Ozdemir O Soylu M Demir AD | 2005 | Angiology2005，56，6： | 1 |
| 19 | Cardiac troponin T as a prognostic marker in patients with heart failure:a 3-year outcome study 显示文摘 | Demir M Kanadasi M Akpinar O | 2007 | Angiology2007，58，5： | 1 |
| 20 | Upper extremity shortness in children with hemiplegic cerebral palsy显示文摘 | Demir S O Oktay F Uysal H | 2006 | J Pediatr Orthop2006，26，6： | 1 |
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