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33篇 您的检索式:作者名="Demchuk M D"
    题名 作者 年代 出处 被引量
1Lesion-symptom mapping with NIHSS sub-scores in ischemic stroke patients显示文摘Background Lesion-symptom mapping(LSM)is a statistical technique to investigate the population-specific relationship between structural integrity and post-stroke clinical outcome.In clinical practice,patients are commonly evaluated using the National Institutes of Health Stroke Scale(NIHSS),an 11-domain clinical score to quantitate neurological deficits due to stroke.So far,LSM studies have mostly used the total NIHSS score for analysis,which might not uncover subtle structure–function relationships associated with the specific sub-domains of the NIHSS evaluation.Thus,the aim of this work was to investigate the feasibility to perform LSM analyses with sub-score information to reveal category-specific structure–function relationships that a total score may not reveal.Methods Employing a multivariate technique,LSM analyses were conducted using a sample of 180 patients with NIHSS assessment at 48-hour post-stroke from the ESCAPE trial.The NIHSS domains were grouped into six categories using two schemes.LSM was conducted for each category of the two groupings and the total NIHSS score.Results Sub-score LSMs not only identify most of the brain regions that are identified as critical by the total NIHSS score but also reveal additional brain regions critical to each function category of the NIHSS assessment without requiring extensive,specialised assessments.Conclusion These findings show that widely available sub-scores of clinical outcome assessments can be used to investigate more specific structure–function relationships,which may improve predictive modelling of stroke outcomes in the context of modern clinical stroke assessments and neuroimaging.Deepthi Rajashekar Matthias Wilms M Ethan MacDonald Serena Schimert Michael D Hill Andrew Demchuk Mayank Goyal Sean P Dukelow Nils Daniel Forkert 2022Stroke & Vascular Neurology2022,7,2:7
2Pre- diction of haematoma growth and outcome in patients with in- tracerebral haemorrhage using the CT-angiography spot sign (PREDICT) a prospective observational study显示文摘Demchuk A M Dowlatshahi D Rodriguez Luna D 2012Lancet Neu- rol2012,11,4:1
3Building a'brain attack'eam to administer thrombolytic therapy for acute ischemic stroke显示文摘 Barber P A Demchuk A M 2000CMAJ2000,162,11:1
4Prediction of haematoma growth and outcome in patients with intracerebral haemorrhage using the CT-angiography spot sign (PREDICT): a prospective observational study显示文摘Demchuk A M Dowlatshahi D Rodriguez-Luna D 2012The Lancet Neurology2012,11,4:1
5Rebleeding leads to poor outcome in ultra-early craniotomy for intracerebral hemorrhage 显示文摘Morgenstem L B Demchuk A M Kim D H 2001Neurology2001,56,7:1
6Predictors of good outcome after intravenous tPA for acute ischemic stroke 显示文摘DEMCHUK A M TANNE D HILL M D 2001Neurology2001,57,3:1
7Noninvasive imaging is improving but digital subtraction angiography remains the Gold standard 显示文摘Hill H D Demchuk A M Frayne R 2007Neurology2007,68,24:1
8Markers of increased risk of intracerehral hemorrhage after intravenous recombinat tissue plasminogen activator therapy foy acute ischemic styoke in clinical practice:the multicenter rt-PA显示文摘TANNE D KASNER S E DEMCHUK A M 2002Stroke Survey Circulation2002,105,14:1
9Transcranial doppler in acute stroke显示文摘Andrew M Demchuk M D Maher Saqqur M D 2005Neuroi Clin North Am2005,15,:1
10Re- bleeding leads to poor outcome in ultra - early craniotomy for in-tracerebral hemorrhage 显示文摘MORGENSTERN L B DEMCHUK A M KIM D H 2001Neurology2001,56,10:1
11Defining hematoma expansion in intracerebral hemorrhage: relationship with patient outcomes显示文摘Dowlatshah D Demchuk A M Flaherty M L 2011Neurology2011,76,14:1
12Role ol transeranial Doppler in neuroeritieal care显示文摘Saqqur M Zygun D Demchuk A 2007Crit Care Med2007,35,5:1
13Rebleeding leads to poor outcome in ultra-early craniotomy for intracerebral hemorrhage 显示文摘MORGENSTERN L B DEMCHUK A M KIM D H 2001Neurology2001,56,10:1
14Serum glucoselevel and diabetes predict tissue plasminogen activator-related intrace-rebral hemorrhage in acute ischemic stroke显示文摘Demchuk A M Morgenstern L B Krieger D W 1999Stroke1999,30,1:1
15Noninvasve imaging isimproving but digital subtraction angiography remains the goldstandard显示文摘Hill M D Demchuk A M Frayne R 2007Neurology2007,68,24:1
16Magnetic resonance imaging and computed tomography in emergency assessment of patients with suspected acute stroke: a prospective comparison显示文摘Julio A Chalela Chelsea S Kidwell Lauren M Nentwich Marie Luby John A Butman Andrew M Demchuk Michael D Hill Nicholas Patronas Lawrence Latour Steven Warach 2007The Lancet2007,,9558:1
17Prediction of haematoma growth and outcome in patients with intracerebral haemorrhage using the CT-angiography spot sign(PREDICT):a prospective observational study显示文摘Demchuk A M Dowlatshahi D Rodriguez-Luna D 2012Lancet Neurol2012,11,4:1
18Rebleeding leads to poor outcome in ultra early craniotomy for intracerebral hemorrha显示文摘Morgenstem L B Demchuk A M Kim D H 2001Neurology2001,56,1:1
19Rebleeding leads to poor outcome in ultraearly craniotomy for intracerebral hemorrhage 显示文摘MORGENSTERN L M DEMCHUK A M KIM D H 2001Neurology2001,56,10:1
20Importance of early ischemic computed tomography changes using ASPECTS in NINDS rtPA Stroke Study显示文摘DEMCHUK A M HILL M D BARBER P A 2005Stroke2005,36,10:1
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