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| 1 | Comparison of Wirsung-jejunal duct-tomucosa and dunking technique for pancreatojejunostomy after pancreatoduodenectomy显示文摘Pancreato-enteric reconstruction after pancreatoduodenectomy (PD) is still a source of debate because of the high incidence of complications. Among the various types of pancreato-jejunostomies we don’t know yet which is the best in terms of anastomotic failure and related complications rates. Wirsung-jejunal duct-to-mucosa anastomosis (WJ) and 'dunking' pancreato-jejunal anastomosis (DPJ) are the two most used ones worldwide but conflicting results are reported. To determine which is the safer anastomosis and to define when an anastomosis should be preferred, we retrospectively reviewed two groups of patients who underwent WJ or DPJ. METHODS:Twenty-three patients underwent PD with WJ (n=17) with dilated (WJD) (n=9) or not-dilated Wirsung’s duct (WJND) (n=8) or with a DPJ (n=6) over a 3-year period at a single institution. RESULTS: The complications rate was high in all groups of patients (33.3% in WJD, 37.5% in WJND and 66.7% in DPJ). A pancreatic fistula developed in one patient in each group (11. 1% in WJD, 12. 5% in WJND and 16. 7% in DPJ). All these patients were managed conservatively. Anastomotic disruption took place in the WJ patients especially in the WJND group (n=2) compared to the WJD (n=1) (25% vs 11.1%) or DPJ groups (0%) : these three patients required a re-operation. Overall, the anastomotic defects were higher in patients who underwent WJND (37.5%), compared to WJD (22.2%) and to DPJ (16.7%). However, no statistical differences were found among the groups. Delayed gastric emptying (DGE) and total parenteral nutrition (TPN) along with anastomotic defects were responsible for a prolonged hospital stay. CONCLUSIONS:Our results were not able to demonstrate any statistical difference between the two different techniques in preventing anastomotic failure. WJ can represent a valid choice in case of a dilated duct and a firm, fibrotic enlarged gland that could not be properly invaginated in a small jejunal loop. DGE may occur in those patients who experienced an anastomotic failure and required a TPN regimen with a prolonged hospital stay. | Unita di Chirurgia, Dipartimento di Fisiopatologia Clinica (Batignani G, Fratini G, Zuckermann M and Tonelli F) and Dipartimento di Statistica (Bianchini E), Universitd degli Studi di Firenze, Flo rence, Italy | 2005 | Hepatobiliary & Pancreatic Diseases International2005，4，3： | 9 |
| 2 | Fas stimulation of T lymphocytes promotes rapid intercellular exchange of death signals via membrane nanotubes显示文摘Fas/CD95 表面受体调停各种各样的房间的快速的死亡打字,包括有为触发 autoimmunity 的潜力的 autoreactive T 房间。这里,我们表明那的船边交货的现在的新奇方面定义一种“社会”的尺寸到导致受体的 apoptosis。船边交货刺激很快导致在附近的 T 房间之间的广泛的膜 nanotube 形成。这极其依赖于 Rho GTPases 然而并非在 caspase 激活上。包括活跃 caspases 的膜和 cytosolic 元素的双向转移能被观察经由这些 nanotubes 发生。Nanotube 形成和死亡信号的细胞间的交换在从有在船边交货受体的自体免疫的 lymphoproliferative 症候群 harbouring 变化的病人的 T 淋巴细胞是有缺点的。我们断定调停 nanotube 的交换组成扩充在附近的 T 房间之间发信号的死亡的繁殖的细胞间的通讯的一种新奇形式。 | Peter D Arkwright Francesca Luchetti Julien Tour Charlotte Roberts Rahna Ayub Ana P Morales Jose J Rodriguez Andrew Gilmore Barbara Canonico Stefano Papa Mauro Degli Esposti | 2010 | Cell Research2010，20，1： | 4 |
| 3 | Geomorphosites: Concepts,methods and examples of geomorphological survey显示文摘Some fundamental concepts on geosites and particularly on geomorphological assets (geomorphosites) are reviewed and a methodology for their survey and assessment is presented and pointed out. Also, a case study in the province of Modena is presented. | Mario PanizzaDipartimento di Scienze della Terra, Universita degli Studi di Modena e Reggio Emilia, Largo S. Eufemia 19-41100, Modena, Italy (e-mail: pit?unimo.it) | 2001 | Chinese Science Bulletin2001，46，S1： | 4 |
| 4 | Soil Properties as Influenced by Incorporation of Crop Residues | A. SCAGNOZZI, R. LEVI-MINZI, A. SAVIOZZI and R. RIFFALDIInstttute of Agricultural Chemistry, University of Pisa, Via S. Michele degli Scalzi 2, 56124 Pisa (Italy) | 1994 | Pedosphere1994，4，3： | 3 |
| 5 | A simple sequence re- peat-based linkage map of barley 显示文摘 | Ramsay L Macaulay M Degli S | 2000 | The Genetics Society of America2000，，： | 1 |
| 6 | TRAIL R2: a novel apoptosis mediating receptor for TRAIL显示文摘 | Walczak H Degli Esposti M A Johnson R S et el | 1997 | EMBO J1997，16，53： | 1 |
| 7 | Mitochondrial membrane permeabilisation by Bax/Bak 显示文摘 | Degli Esposti M Dive C | 2003 | Biochem Biophys Res Commun2003，304，3： | 1 |
| 8 | Thyroid papillary microcarcinoma: a descriptive and mela-analysis study显示文摘 | ROTI E DEGLI UBERTI E C BONDANELLI M | 2008 | Eur J Endocrinol2008，159，： | 1 |
| 9 | Thyroid papillary micro- carcinoma: a descriptive and meta-analysis study显示文摘 | Roti E Degli UE Bondanelli M | 2008 | Eur J En- docrinol2008，159，6： | 1 |
| 10 | Witmin E therapy of acute CC14- induced hepatic injury in mice is associated with inhibition of nuclear factor Kappon B binding 显示文摘 | Liu S L Degli Esposti S | 1995 | Hepatology1995，22，5： | 1 |
| 11 | Identification of microsatellite markers and their application to population genetics of Venturia inqequalis 显示文摘 | Tenzer I Degli I S Morgante M | 1999 | Phytopathology1999，89，： | 1 |
| 12 | Treatment of conjunctival aquarnous cell carcinoma with topical 5-fluorouracil显示文摘 | Edoardo Midena Claudia Degli Angeli Massimo Valenti | 2000 | Br J Ophthalmol2000，84，3： | 1 |
| 13 | A simple sequence repeat-based linkage map of barley显示文摘 | Ramsay L Macaulay M Degli S I | 2000 | Genetics2000，156，20： | 1 |
| 14 | Macular function impairment in eyes with early age-related mac- ular degeneration 显示文摘 | Midena E Degli Angeli C Blarzino MC Valenti M Segato T | 1997 | Invest Ophthalmol Vis Sci1997，38，2： | 1 |
| 15 | Mitochondria and cells produce reactive oxygen species in virtual anaerobiosis:relevance to ceramide-induced apoptosis显示文摘 | Degli Espositi M Mclennan H | 1998 | FEBS Lett1998，430，： | 1 |
| 16 | Thyroid papillary microcarcinoma: a descriptive and meta-analysis study显示文摘 | Roti E degli Uberti EC Bondanelli M | 2008 | Eur J Endocrinol2008，159，6： | 1 |
| 17 | Molecular epidemiology study of exogenous reinfection in an area with a low incidence of tuberculosis显示文摘 | Bandera A Gori A Catozzi L Degli Esposti A Marchetti G Molteni C Ferrario G Codecasa L Penati V Matteelli A Franzetti F | 2001 | J Clin Microbiol2001，39，6： | 1 |
| 18 | Discriminating dynamical from additive noise in the Van der Pol oscillator显示文摘 | Degli Esposti Boschi C Ortega G J Louis E | 2002 | Phusica Ser D2002，171，5： | 1 |
| 19 | Measuring mitochondrial reactive oxygen species显示文摘 | Mauro Degli Esposti | 2002 | Methods2002，，4： | 1 |
| 20 | Cloning and characterization of TRAIL-R3,a vovel member of the emerging TRAIL receptor family显示文摘 | Degli Esposti MA Smolak PJ Walczak H | 1997 | J Exp Med1997，186，： | 1 |
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