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| 1 | Chemical weathering intensity and element migration features of the Xiashu loess profile in Zhenjiang, Jiangsu Province显示文摘在 Zhenjiang 的 Xiashu 黄土侧面的化学捱过紧张和元素迁居特征在这篇论文被学习。(1 ) Xiashu 黄土侧面经历了中等化学捱过。看起来降水是更重要的 | CHEN Yingyong LI Xusheng HAN Zhiyong YANG Shouye WANG Yongbo YANG Dayuan | 2008 | Journal of Geographical Sciences2008，18，3： | 25 |
| 2 | Genomic footprints of Kam Sweet Rice domestication indicate possible migration routes of theDongpeople inChina andprovide resources for future rice breeding显示文摘The Dong people are one of China’s 55 recognized ethnic minorities,but there has been a long-standing debate about their origins.In this study,we performed whole-genome resequencing of Kam Sweet Rice(KSR),a valuable,rare,and ancient rice landrace unique to the Dong people.Through comparative genomic analyses of KSR and other rice landraces from south of the Yangtze River Basin in China,we provide evidence that the ancestors of the Dong people likely originated from the southeast coast of China at least 1000 years ago.Alien introgression and admixture in KSR demonstrated multiple migration events in the history of the Dong people.Genomic footprints of domestication demonstrated characteristics of KSR that arose from artificial selection and geographical adaptation by the Dong people.The key genes GS3,Hd1,and DPS1(related to agronomic traits)and LTG1 and MYBS3(related to cold tolerance)were identified as domestication targets,reflecting crop improvement and changes in the geographical environment of the Dong people during migration.A genome-wide association study revealed a candidate yield-associated gene,Os01g0923300,a specific haplotype in KSR that is important for regulating grain number per panicle.RNA-sequencing and quantitative reverse transcription-PCR results showed that this gene was more highly expressed in KSR than in ancestral populations,indicating that it may have great value in increasing yield potential in other rice accessions.In summary,our work develops a novel approach for studying human civilization and migration patterns and provides valuable genomic datasets and resources for future breeding of high-yield and climate-resilient rice varieties. | Chunhui Liu Tianyi Wang Huicha Chen Xiaoding Ma Chengzhi Jiao Di Cui Bing Han Xiaobing Li Aixia Jiao Renchao Ruan Dayuan Xue Yanjie Wang Longzhi Han | 2023 | Molecular Plant2023，16，2： | 3 |
| 3 | Microsatellite DNA analysis proves nucleus of interspecies reconstructed blastocyst coming from that of donor giant panda显示文摘A method for DNA isolation from early development of blastocyst and further analysis of nuclear and mitochondrial DNA was developed in present study. Total DNA was prepared from interspecies reconstructed blastocyst and a giant panda specific microsatellite locus g010 was successfully amplified. DNA sequencing of the PCR product showed that two sequences of reconstructed blastocysts are the same as that of positive control giant panda. Our results prove that the nucleus of interspecies reconstructed blastocyst comes from somatic nucleus of donor giant panda. | DING Bo SHI Peng XIANGYU Jinggong ZHANG Yaping CHEN Dayuan SUN Qingyuan LI Guangpeng WANG Minkang LIU Yilong KANG Li HAN Zhiming SONG Xiangfen LI Jingsong CHEN Yuchun | 2000 | Chinese Science Bulletin2000，45，20： | 3 |
| 4 | Hypertrophic cardiomyopathy: Can the noninvasive diagnostic testing identify high risk patients?显示文摘Hypertrophic cardiomyopathy(HCM) is the most common cause of sudden cardiac death(SCD) in the young, particularly among athletes. Identifying high risk individuals is very important for SCD prevention. The purpose of this review is to stress that noninvasive diagnostic testing is important for risk assessment. Extreme left ventricular hypertrophy and documented ventricular tachycardia and fibrillation increase the risk of SCD. Fragmented QRS and T wave inversion in multiple leads are more common in high risk patients. Cardiac magnetic resonance imaging provides complete visualization of the left ventricular chamber, allowing precise localization of the distribution of hypertrophy and measurement of wall thickness and cardiac mass. Moreover, with late gadolinium enhancement, patchy myocardial fibrosis within the area of hypertrophy can be detected, which is also helpful in risk stratification. Genetic testing is encouraged in all cases, especially in those with a family history of HCM and SCD. | Li Zhang Obinna Mmagu Liwen Liu Dayuan Li Yuxin Fan Adrian Baranchuk Peter R Kowey | 2014 | World Journal of Cardiology2014，6，8： | 3 |
| 5 | Relationship between Chief Executive Officer characteristics and corporate environmental information disclosure in Thailand显示文摘This study focuses on the influence of Chief Executive Officer(CEO)characteristics on environmental information disclosure(EID)in the annual reports of companies listed on the Stock Exchange of Thailand.A regression analysis method is used to explore the relationship between CEO characteristics and corporate environmental disclosure.Pollution-intensive companies are taken as the samples in this study.Results show that financial expertise,educational level,and tenure of CEOs are positively correlated with corporate EID.By contrast,age or gender of CEOs is insignificantly related to EID. | Dayuan LI Aiqi LIN Lu ZHANG | 2019 | Frontiers of Engineering Management2019，6，4： | 3 |
| 6 | Effects of ubiquitin-protea-some pathway on mouse sperm capacitation, acrosome reaction and in vitro fertilization显示文摘Chlortetracycline (CTC) fluorescence patterns were used to study changes in the patterns B and AR of mouse sperm after incubation with reagents that would block the UPP. They were the monoclonal antibody againstubiquitinated proteins——UCPi; the polyclonal antibodyagainst ubiquitin-anti-Ub, and a special inhibitor againstproteasome——ALLN. Furthermore, we treated the capaci-tated sperm or the eggs with these reagents separately and tested whether the normal in vitro fertilization was blocked or not. Results illustrate that UCP1, anti-Ub, and ALLN have little effects on sperm capacitation and acrosome reaction, but they do inhibit fusion of mouse sperm with eggs, which suggests that UPP play an important role in mouse in vitro fertilization. | WANG Hongmei SONG Changcheng DUAN Chongwen SHI Weixian LI Cunxi CHEN Dayuan WANG Yongchao | 2002 | Chinese Science Bulletin2002，47，2： | 2 |
| 7 | Serial nuclear transfer improves the development of interspecies reconstructed giant panda (Aluropoda melanoleucd) embryos显示文摘Interspecies somatic nuclear transfer (NT) may provide a new approach for preservation of the endangered rare species. Previous interspecies cloning studies have shown that a nucleus from a quiescent somatic cell supports early development of reconstructed embryos in the ooplasm from another species. In this study, we transferred nonqui-escent somatic cells from a giant panda into the perivitelline space of the enucleated rabbit oocytes. After electrofusion (at the rate of 71.6%) and electrical activation, 4.2% of the panda-rabbit reconstructed embryos developed to blastocyst in vitro. For improving the development rate of reconstructed embryos, we used serial NT in this study, i.e. blas-tomeres from reconstructed morulae were transferred into the perivitelline space of the enucleated rabbit oocytes. The fusion rates in the groups of serial I, serial Ⅱ and serial Ⅲ were 79.5%, 84.1% and 78.0%, respectively, having no difference with that of somatic group. And the blastocyst rates in serial NT groups | LI Jinsong CHEN Dayuan HAN Zhiming ZHU Ziyu WEN Duancheng SUN Qingyuan LIU Zhonghua WANG Minkang LIAN Li DU Jun WANG Pengyan ZHANG Hemin | 2002 | Chinese Science Bulletin2002，47，6： | 2 |
| 8 | Modulation of constitutive nitric oxide synthase, Bcl - 2 and Fas expression in cultured human voronary endothelial cells exposed to anoxia - reoxygenation and angiotensin II : role of AT1 receptor activation显示文摘 | Dayuan Li Kathleen Tomson | 1999 | Cardiovascular Research1999，41，： | 1 |
| 9 | Nanopolyphenol rejuvenates microglial surveillance of multiple misfolded proteins through metabolic reprogramming显示文摘Microglial surveillance plays an essential role in clearing misfolded proteins such as amyloid-beta,tau,andα-synuclein aggregates in neurodegenerative diseases.However,due to the complex structure and ambiguous pathogenic species of the misfolded proteins,a universal approach to remove the misfolded proteins remains unavailable.Here,we found that a polyphenol,α-mangostin,reprogrammed metabolism in the disease-associated microglia through shifting glycolysis to oxidative phosphorylation,which holistically rejuvenated microglial surveillance capacity to enhance microglial phagocytosis and autophagy-mediated degradation of multiple misfolded proteins.Nanoformulation ofα-mangostin efficiently deliveredα-mangostin to microglia,relieved the reactive status and rejuvenated the misfolded-proteins clearance capacity of microglia,which thus impressively relieved the neuropathological changes in both Alzheimer’s disease and Parkinson’s disease model mice.These findings provide direct evidences for the concept of rejuvenating microglial surveillance of multiple misfolded proteins through metabolic reprogramming,and demonstrate nanoformulatedα-mangostin as a potential and universal therapy against neurodegenerative diseases. | Dayuan Wang Xiao Gu Xinyi Ma Jun Chen Qizhi Zhang Zhihua Yu Juan Li Meng Hu Xiaofang Tan Yuyun Tang Jianrong Xu Minjun Xu Qingxiang Song Huahua Song Gan Jiang Zaiming Tang Xiaoling Gao Hongzhuan Chen | 2023 | Acta Pharmaceutica Sinica B2023，13，2： | 1 |
| 10 | LOX-1,an oxidized LDL endothelial receptor,induces CD40/CD40L signaling in human coronary artery endothelial cells显示文摘 | Dayuan Li Ling Liu Hongjiang Chen Tatsuya Sawamura Mehta JL | 2003 | Arterioscler Thromb Vasc Biol2003，23，： | 1 |
| 11 | Role of Caspases in Ox-LDL–Induced Apoptotic Cascade in Human Coronary Artery Endothelial Cells显示文摘 | Jiawei Chen Jawahar L. Mehta Nezam Haider Xingjian Zhang Jagat Narula Dayuan Li | 2004 | Circulation Research: Journal of the American Heart Association2004，，3： | 1 |
| 12 | Ground-dwelling birds near the Qinghai-Tibet highway and railway显示文摘 | Zhongqiu Li Chen Ge Jing Li Yankuo Li Aichun Xu Kexin Zhou Dayuan Xue | 2010 | Transportation Research Part D2010，，8： | 1 |
| 13 | The theory and experiment of very-long-wavelength 256×1 GaAs/Al_(x)Ga_(1-x)As quantum well infrared detector linear arrays显示文摘The 256×1 linear array of multiple quantum wells infrared photodetector (QWIP) is designed and fabricated for the peak response wavelength at λP=14.6 μm. The response spectral width is bigger than 2.2 μm. The two-dimensional (2D) diffractive coupling grating has been formed on the top QWIP photosensitive pixel for coupling the infrared radiation to the infrared detective layers. The performance of the device at VB=3 V and T=45 K has the responsibility 4.28×10-2 (A/W), the blackbody detectivity Db*=5.14×109 (cm·Hz1/2/W), and the peak detectivity Dλ*=4.24× 1010 (cm·Hz1/2/W). The sensor pixels are connected with CMOS read out circuit (ROC) hybridization by indium bumps. When integral time is 100 μs, the linear array has the effective pixel of QWIP FPA Nef of 99.2%, the average responsibility (V/W) of 3.48×106 (V/W), the average peak detectivity Dλ* of 8.29×109 (cm·Hz1/2/W), and the non-uniformity UR of 5.83%. This device is ready for the thermal image application. | GUO FangMin LI Ning XIONG DaYuan ZHEN HongLou XU XiangYan HOU Ying DING RuiJun LU Wei HUANG Qi ZHOU JunMing | 2008 | Science China(Physics,Mechanics & Astronomy)2008，51，7： | 1 |
| 14 | Chemical weathering of the loess deposits in the lower Changjiang Valley, China, and paleoclimatic implications显示文摘 | YANG Shouye LI Congxian YANG Dayuan | 2004 | Quaternary International2004，117，： | 1 |
| 15 | MehtalTGF-β1 attenuates myocardial ischemia-reperfusion injury via inhibition of upregulation of MMP-1 显示文摘 | Hongjiang Chen Dayuan Li Tom Saldeen | 2003 | Am J Physiol Heart Circ Physiol2003，284，： | 1 |
| 16 | Inhibitory effect of candesartan and rosuvastatin on CD40 and MMPs expression in Apo-E knockout mice :Novel insights into the role of RAS and dyslipidemia in atherogenesis 显示文摘 | Chen Jiawei Li Dayuan Schaefer | 2004 | Cardiovascular Pharmacology2004，44，4： | 1 |
| 17 | MAPK regulates cell cycle progression in pig oocytes and fertilized eggs显示文摘Oocytes collected from prepubertal gilt ovaries were matured in vitro (IVM), and fertilized in vitro (IVF) or electrically activated. Phosphorylation of mitogen-activated protein kinase (MAPK) was detected with SDS-PAGE and Western blotting, and translocation of ERK2 was observed with immunofluorescent cytochemistry. We found that the quantity of MAPK kept unchanged during oocyte maturation. There was no phosphorylated MAPK in porcine oocytes at the germinal vesicle (GV) stage; a little MAPK was phosphorylated at 20 h of IVM; a high level phosphory-lation was detected at 30 h, while MAPK phosphorylation decreased at 36 h; and then MAPK phosphorylation increased again to the peak level from 40 to 60 h. ERK2 translocated from the peripheral cytoplasm to inner cytoplasm and nuclear area during oocyte maturation. There was nearly no phosphorylated MAPK at 18 and 20 h of electrically activated oocytes, but phosphorylation increased at 22 h. There was no phosphorylated MAPK at 12 h of IVF, while | LI Manyu FAN Hengyu TONG Chao CHEN Dayuan XIA Guoliang SUN Qingyuan | 2002 | Chinese Science Bulletin2002，47，10： | 1 |
| 18 | Statins modulate oxidized low-density lipoprotein-mediated adhesion molecule expression in human coronary artery endothelial cells: role of LOX-1 显示文摘 | Dayuan Li Hong~iang Chen Romeo F | 2002 | J Pharmacol Exp Ther2002，302，2： | 1 |
| 19 | Identification,regulation and fuction of a novellectin-like oxidized low-density lipoprotein receptor显示文摘 | Jawahar L Mehta Dayuan Li | 2002 | J Am Coll Cardiol2002，，39： | 1 |
| 20 | Role of Caspases in Ox-LDL–Induced Apoptotic Cascade in Human Coronary Artery Endothelial Cells显示文摘 | Jiawei Chen Jawahar L. Mehta Nezam Haider Xingjian Zhang Jagat Narula Dayuan Li | 2004 | Circulation Research: Journal of the American Heart Association2004，，3： | 1 |
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