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1肺癌患者入院时下肢深静脉血栓的发生率及相关危险因素分析显示文摘背景与目的静脉血栓栓塞症(venous thromboembolism, VTE)是一种公认的在肺癌患者中有较高发病率和死亡率的并发症。本研究目的是明确我们中心肺癌患者入院时下肢深静脉血栓(lower extremity venous thrombosis, LEDVT)的发生率,并揭示其入院时LEDVT发生的危险因素。方法选择天津医科大学总医院肺部肿瘤外科在2017年7月-2017年12月收治的231例肺癌患者,入院时即行双下肢静脉彩超检查,以分析肺癌患者LEDVT的发生率;同时,对肺良性疾病患者入院时LEDVT的发生率进行比较。在肺癌患者中,进一步分析LEDVT发生与其临床特征的关系,寻找LEDVT发生的可能危险因素;同时,亦分析这些患者的血浆D-二聚体(D-Dimmer)、纤维蛋白原(fibrinogen, FIB)、凝血酶时间(thrombin time, TT)、活化部分凝血酶时间(activated partial thrombin time,APTT)、凝血酶原时间(prothrombin time, PT)及血小板(platelet, PLT)之间的差异。结果在231例肺癌患者中,入院时发生LEDVT者12例,其发生率为5.2%(12/231);而77例肺良性疾病患者入院时均未查见LEDVT的发生,提示肺癌患者入院时LEDVT的发生率明显高于肺良性疾病(P<0.05)。在肺癌患者中进一步分析发现,伴有远处转移(包括N3淋巴结转移)的肺癌患者较不伴有转移者更易发生LEDVT(11.29%, 7/62 vs 2.96%, 5/169)(P<0.05)。肺癌LEDVT组患者入院时的D-Dimer的中位值为1,534mg/L(369 mg/L-10,000 mg/L),明显高于非LEDVT组患者(539 mg/L, 126 mg/L-1,000 mg/L)(P<0.05);而FIB、TT、APTT、PT和PLT在两组患者之间无明显统计学差异(P>0.05)。结论我们中心肺癌患者入院时LEDVT总体发生率约为5%,明显高于肺良性疾病患者。入院时伴有远处转移(包括N3淋巴结转移)的肺癌患者更易发生LEDVT,其中,D-Dimer值较高的患者应考虑到VTE事件发生的可能。杜晖 赵洪林 李梅 纪慧慧 任凡 王攀 李昕 董明 Rehman DAWAR 陈钢 陈军 2018中国肺癌杂志2018,21,10:33
2Corporate social responsibility and consumers’ attributions and brand evaluations in a product–harm crisis显示文摘Jill Klein Niraj Dawar 2004International Journal of Research in Marketing2004,,3:4
3Effects of the nitrification inhibitor nitrapyrin and tillage practices on yield-scaled nitrous oxide emission from a maize field in Iran显示文摘Nitrification inhibitors can effectively decrease nitrification rates and nitrous oxide(N_(2)O)emission while increasing crop yield under certain conditions.However,there is no information available on the effects of nitrification inhibitors and tillage practices on N_(2)O emissions from maize cropping in Iran.To study how tillage practices and nitrapyrin(a nitrification inhibitor)affect N_(2)O emission,a split factorial experiment using a completely randomized block design with three replications was carried out in Northeast Iran,which has a cold semiarid climate.Two main plots were created with conventional tillage and minimum tillage levels,and two nitrogen(N)fertilizer(urea)management systems(with and without nitrapyrin application)were created as subplots.Tillage level did not have any significant effect on soil ammonium(NH_(4)^(+))and nitrate(NO_(3)^(-))concentrations,cumulative amount and yield-scaled N_(2)O emission,and aboveground biomass of maize,whereas nitrapyrin application showed significant effect.Nitrapyrin application significantly reduced the cumulative amount of N_(2)O emission by 41%and 32%in conventional tillage and minimum tillage practices,respectively.A reduction in soil NO_(3)^(-)concentration by nitrapyrin was also observed.The average yield-scaled N_(2)O emission was 13.6 g N_(2)O-N kg^(-1)N uptake in both tillage systems without nitrapyrin application and was significantly reduced to 7.9 and 8.2 g N_(2)O-N kg^(-1)N uptake upon the application of nitrapyrin in minimum tillage and conventional tillage practices,respectively.Additionally,nitrapyrin application increased maize biomass yield by 4%and 13%in the minimum tillage and conventional tillage systems,respectively.Our results indicate that nitrapyrin has a potential role in reducing N_(2)O emission from agricultural systems where urea fertilizers are broadcasted,which is common in Iran due to the practice of traditional farming.Azam BORZOUEI Ulo MANDER Alar TEEMUSK Alberto SANZ-COBENA Mohammad ZAMAN Dong-Gill KIM Christoph MÜLLER Ali Askary KELESTANIE Parvaneh SAYYAD AMIN Ebrahim MOGHISEH Khadim DAWAR Ana Gabriela PÉREZ-CASTILLO 2021Pedosphere2021,31,2:4
4Miniaturized UWB multi-resonance patch antenna loaded with novel modified H-shape SRR metamaterial for microspacecraft applications显示文摘本文设计并分析了一种改进H形裂环谐振器(split ring resonator,SRR)的新型超材料。它具有负磁导率和负介电常数特性,且在X,Ku和Ka频带内具有多频共振特性。本文就超材料方向和位置的变化对不同配置下的贴片天线进行了分析。结果表明,新型超材料天线实现了性能优化,表现为9 d B的可观增益,77 GHz的带宽,100%的辐射效率,以及有源区65%的面积缩减。二阶分形超材料天线尺寸降至1/21,从而实现了高度小型化。该研究为急需小尺寸尖波束的通信领域提供了一种解决方案。Parul DAWAR N. S. RAGHAVA Asok DE 2017Frontiers of Information Technology & Electronic Engineering2017,18,11:3
5Brand crises: The roles of brand familiarity and crisis relevance in determining the impact on brand evaluations显示文摘Niraj Dawar Jing Lei 2008Journal of Business Research2008,,4:2
6Traditional Indian anti-diabetic plants attenuate progression of renal damage in streptozotocin induced diabetic mice显示文摘J.K Grover V Vats S.S Rathi R Dawar 2001Journal of Ethnopharmacology2001,,3:2
7Effects of the nitrification inhibitor nitrapyrin and the plant growth regulator gibberellic acid on yield-scale nitrous oxide emission in maize fields under hot climatic conditions显示文摘Nitrification inhibitors are widely used in agriculture to mitigate nitrous oxide(N_(2)O)emission and increase crop yield.However,no concrete information on their mitigation of N_(2)O emission is available under soil and environmental conditions as in Pakistan.A field experiment was established using a silt clay loam soil from Peshawar,Pakistan,to study the effect of urea applied in combination with a nitrification inhibitor,nitrapyrin(2-chloro-6-tri-chloromethyl pyridine),and/or a plant growth regulator,gibberellic acid(GA_3),on N_(2)O emission and the nitrogen(N)uptake efficiency of maize.The experimental design was a randomized complete block with five treatments in four replicates:control with no N(CK),urea(200 kg N ha^(-1))alone,urea in combination with nitrapyrin(700 g ha^(-1)),urea in combination with GA_3(60 g ha^(-1)),and urea in combination with nitrapyrin and GA_3.The N_(2)O emission,yield,N response efficiency,and total N uptake were measured during the experimental period.The treatment with urea and nitrapyrin reduced total N_(2)O emission by 39%–43%and decreased yield-scaled N_(2)O emission by 47%–52%,relative to the treatment with urea alone.The maize plant biomass,grain yield,and total N uptake increased significantly by 23%,17%,and 15%,respectively,in the treatment with urea and nitrapyrin,relative to the treatment with urea alone,which was possibly due to N saving,lower N loss,and increased N uptake in the form of ammonium;they were further enhanced in the treatment with urea,nitrapyrin,and GA_3 by 27%,36%,and 25%,respectively,probably because of the stimulating effect of GA_3 on plant growth and development and the reduction in biotic and abiotic stresses.These results suggest that applying urea in combination with nitrapyrin and GA_3 has the potential to mitigate N_(2)O emission,improve N response efficiency,and increase maize yield.Khadim DAWAR Kamil SARDAR Mohammad ZAMAN Christoph MÜLLER Alberto SANZ-COBENA Aamir KHAN Azam BORZOUEI Ana Gabriela PÉREZ-CASTILLO 2021Pedosphere2021,31,2:2
8The dysregulated autophagy signaling is partially responsible fordefective podocyte development in wt1a mutant zebrafish显示文摘Podocytes are essential elements of the glomerular filtration barrier and relevant to many kidney diseases.But the molecular mechanism in podocyte development is still unclear.Wilms tumor protein(WT1)is an essential factor for urogenital system development.Zebrafish have two wt1 genes,naming wt1a and wt1b.Here,we examined the roles of both wt1 genes in zebrafish embryonic development employing the CRISPR/Cas9 technology.The homozygous wt1a mutants displayed developmental malformations including pericardial edema,yolk sac edema and failure of glomerulus development.Loss of wt1a function disrupted podocyte differentiation and inhibited expression of podocin and nephrin.In contrast,the homozygous wt1b mutants were phenotypically normal and had no severe phenotypes of nephrogenesis defects that were observed in wt1b morpholino knockdown embryos.Therefore,wt1a plays an essential role in kidney development,whereas wt1b might not be essential for kidney development.Interestingly,from previous studies we knew that autophagy is involved in podocyte differentiation.By detecting the protein level of P62 and LC3A/B,we found the autophagy signal was greatly reduced in wt1a mutants.To better understand the relationship between autophagy signal and wt1a function in podocyte development,rapamycin was added to activate autophagy in wt1a-mutated embryos.As a result,podocyte injury was ameliorated in wt1a homozygous mutants by rapamycin treatment.In conclusion,our findings not only confirmed the essential function of wt1a during kidney development,but also provided a possible way for treatment of diseases involving podocyte injury.Xuemei Zhang Qiaohong Lin Fan Ren Jin Zhang Farman Ullah Dawar Jie Mei 2018Aquaculture and Fisheries2018,3,3:2
9Impact of product-harm crisis on brand equity,the moderating role of consumer expectations显示文摘Dawar N Pillutla M M 2000Journal of Marketing Research2000,37,2:1
10Product - Harm Crises and the Signaling Ability of Brands显示文摘Dawar Niraj 1998International Studies of Management & Organization1998,28,3:1
11Impact of Product- Harm Crises on Brand Equity: The Moderating Role of Consumer Expectations 显示文摘Niraj Dawar Marian 2000Journal of Marketing Research2000,3,1:1
12Affine systems of equations and counting infinitary logic 显示文摘Atserias A Bulatov A Dawar A 2009Theoretical Computer Science2009,410,18:1
13Marketing universals: Consumers use of brand name, price, physical appearance, and retailer reputation as signals of product quality显示文摘Dawar N Parker P 1994Journal of Marketing1994,58,2:1
14Corporate Social Responsibility and Consumers' Attributions and Brand Evaluations in a Product-Harm Crisis 显示文摘Jill Klein Niraj Dawar 2004International Journal of Research in Marketing2004,21,3:1
15Brand crises: The roles of brand familiarity and crisis relevance in determining the impact on brand evaluations 显示文摘Niraj Dawar Jing Lei 2009Journal of Business Research2009,,62:1
16Effect of laser irradiation on the responsivity of mercury cadmium telluride detectors显示文摘Arora V K Dawar A L 1996Infrared Physics and Technology1996,37,2:1
17Brand crises : The roles of brand fa- miliarity and crisis relevance in determining the im- pact on brand evaluations 显示文摘Dawar N Lei J 2009Journal of Business Research2009,62,4:1
18Effect of laser irradiation on structural,electrical,and optical properties of p-mercury cadmium telluride显示文摘Dawar A L Savita Roy Mall R P 1991J Appl Phys1991,70,7:1
19Corporate social responsibility and consumers' attributions and brand evaluations in a product -harm crisis 显示文摘Klein J Dawar N 2004International Journal of research in Marketing2004,21,3:1
20The Impact of Information Characteristics on Negative Spillover Effects in Brand Portfolios显示文摘Jing Lei Niraj Dawar Jos Lemmink 0,,33:1
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