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| 1 | 重载列车系统的动力效应对铁路斜拉桥地震响应的影响显示文摘本文为了评估重载列车系统的动力效应对大跨度铁路桥梁地震响应的影响,研究了重载列车静止在铁路斜拉桥上时的动力特性以及地震响应,采用了基于多刚体力学的空间车辆模型与附加质量模型两种不同的方式对车辆进行建模。计算中考虑了桥梁的几何非线性,并采用了三类地震波进行数值模拟。在对比有无车辆情况下的桥梁响应时,考虑了重载货车满载以及空载的因素。结果表明,在地震发生时,满载的列车会使得主梁弯矩以及拉索的索力峰值分别增加80%与40%,但是主梁的加速度峰值则会显著下降。证明了重载列车存在一定阻尼效应,且该阻尼效应对于满载列车来说更为显著。在此基础上,提出了一种用于桥梁抗震验算的简化2自由度车辆模型,并证明了其可靠性。 | 朱志辉 龚威 王琨 刘宇 DAVIDSON Michael T 蒋丽忠 | 2020 | Journal of Central South University2020,27,7: | 5 |
| 2 | Fondaparinux预防老年急性内科患者发生静脉血栓形成的效果与安全性:随机安慰剂对照研究显示文摘目的:观察 Fondaparinux 对具有中高度静脉血栓发生危险的老年急性内科住院患者的抗凝效果与安全性。设计:双盲随机安慰剂对照研究。背景:8个国家的35个中心。参与者:849例≥60岁内科患者,住院原因分别为充血性心力衰竭、慢性肺病合并急性呼吸系统疾患、急性炎症性或感染性疾病,预期至少住院4天以上。干预:2.5 mg Fondaparinux 或安慰剂,每天1次皮下注射,持续6~14天。观察指标:主要指标为静脉血栓形成(治疗后15天内采用双侧静脉造影检查)及有症状的静脉血栓;次要指标为死亡与出血。患者随访时间为1个月。结果:Fondaparinux 治疗组425例患者和安慰剂组414例患者接受了安全性分析(10例未治疗)。644例患者(75.9%)可接受主要指标分析。静脉血栓检出率在 Fondaparinux 治疗组为5.6%(18/321),安慰剂组为10.5%(34/323),相对危险减少46.7%(95% CI 7.7%~69.3%)。安慰剂组5例患者发生有症状的静脉血栓,Fondaparinux治疗组无患者发生有症状的静脉血栓(P=0.029)。两组均有1例(0.2%)患者发生严重出血。随访结束时,安慰剂组、Fondaparinux 治疗组分别死亡25(6.0%)、14(3.3%)例患者。结论:Fondaparinux 可有效预防急性内科老年患者无症状性及有症状的静脉血栓。严重出血几率两组相似。 | Alexander T Cohen Bruce L Davidson Alexander S Gallus Michael R Lassen Martin H Prins Witold Tomkowski Alexander G G Turpie Jan F M Egberts Anthonie W A Lensing 石汉平(译) 王深明(校) | 2006 | 英国医学杂志中文版2006,9,5: | 3 |
| 3 | Endothelin-1 activation in pediatric patients undergoing surgical coarctation of the aorta repair显示文摘AIM To determine endothelin-1(ET-1)concentration before and after surgical coarctectomy and evaluate its association with left ventricular geometric change.METHODSA prospective,cohort study of 24 patients aged 2 d to 10years with coarctation of the aorta undergoing surgical repair.A sub-cohort of patients with age<1 mo was classified as'neonates'.Echocardiograms were performed just prior to surgery and in the immediate post-op period to assess left ventricle mass index and relative wall thickness(RWT).Plasma ET-1 levels were assessed at both time points.Association between ET-1 levels and ventricular remodeling was assessed.RESULTSPatients<1 year demonstrated higher pre-op ET-1 than post-op(2.8 pg/m L vs 1.9 pg/m L,P=0.02).Conversely,patients>1 year had no change in ET-1 concentration before and after surgery(1.1 vs 1.4,NS).Pre-op,patients<1 year demonstrated significantly higher ET-1 than older children(2.8 vs 1.1,P=0.001).Post-op there was no difference between the age groups(1.9 vs 1.4,NS).Neither RWT nor left ventricle mass index(LVMI)varied from pre-op to post-op.The subset of neonates showed a strong positive correlation between pre-op ET-1 and RWT(r=0.92,P=0.001).Patients with ET-1>2 pg/m L preop demonstrated higher LVMI(65.7 g/m^(2.7) vs 38.5 g/m^(2.7),P=0.004)and a trend towards higher RWT(45%vs39%,P=0.07)prior to repair than those with lower ET-1concentration.CONCLUSIONET-1 concentration is significantly variable in the perioperative period surrounding coarctectomy.Older children and infants have different responses to surgical repair suggesting different mechanisms of activation. | Benjamin Steven Frank Tracy T Urban Suhong Tong Courtney Cassidy Max B Mitchell Christopher S Nichols Jesse A Davidson | 2017 | World Journal of Cardiology2017,9,12: | 2 |
| 4 | Activation of the Lime-Flyash Reaction by Trace Chemical显示文摘 | D·T·Davidson | 1996 | HRB Bull1996,,: | 1 |
| 5 | Ezetimibe coadministered with simvastatin In patients with primary hypercholesterolemia显示文摘 | DAVIDSON MH MCGARRY T BETTIS R | 2002 | J Am Coll Cardiol2002,40,12: | 1 |
| 6 | 显示文摘 | Uhlmann D R Suratwala T Davidson K | 1997 | J Non-Cryst Solids1997,218,: | 1 |
| 7 | Interleukin - 2 sig -naling via STAT5 constrains T helper 17 cell generation显示文摘 | Laurence A Tato C M Davidson T S | 2007 | Im- munity2007,26,3: | 1 |
| 8 | A preliminary cost curve assessment of carbon dioxide capture and storage potential in China显示文摘 | Dahowski R T Li X Davidson C L | 2009 | Energy ProcedJa2009,1,1: | 1 |
| 9 | Quasi-Maximum-Likelihood Multiuser Detection Using Semi-Definite Relaxation with Application to Synchronous CDMA 显示文摘 | MA W-K DAVIDSON T WONG K | 2002 | IEEE Transactions on Signal Processing2002,50,4: | 1 |
| 10 | Resilience in response to life stress: the effects of coping style and cognitive hardiness显示文摘 | BEASLEY M THOMPSON T DAVIDSON J | 2003 | Personality and Individual Differences2003,,34: | 1 |
| 11 | The prediction of patti- cle cluster properties in the near wall region of a vertical riser显示文摘 | Harris A T Davidson J F Thorpe R B | 2002 | Powder Technology2002,127,2: | 1 |
| 12 | Type I and type III interferons drive redundant amplification loops to induce a transcriptional signature in influenza-infected airway epithelia显示文摘 | Crotta S Davidson S Mahlakoiv T | 2013 | PLoS Pathog2013,9,10: | 1 |
| 13 | Development of a new resilience scale:the Connor-Davidson Resilience Scale (CD-RISC)显示文摘 | Connor K M Davidson J R T | | 0,,02: | 1 |
| 14 | Fluidized sand biofilters used to remove ammonia, biochemical oxygen demand, total coliform bacteria, and suspended solids from an intensive aquaculture effluent 显示文摘 | Davidson J Helwig N Summerfelt S T | 2008 | Aquaeultuml Engineering2008,39,1: | 1 |
| 15 | Pharmacology, pharmacokinetics and practical applications of borlezomib显示文摘 | Schwartz R Davidson T | 2004 | Oncology (Williston Park)2004,18,1411: | 1 |
| 16 | Fluorescent tracking of nickel ions in human cultured cells显示文摘 | Ke Q Davidson T Kluz T | 2007 | Toxicology and Applied Pharmacology2007,219,: | 1 |
| 17 | Development of a new resilience scale: The Connor-Davidson Resilienee Scale (CD-RISC) 显示文摘 | Connor K M Davidson J R T | 2003 | Depression and Anxiety2003,18,: | 1 |
| 18 | Efficacy of sertraline in preventing relapse of posttraumatic stress disorder:results of a 28 - week double - blind, placebo - controlled study 显示文摘 | Davidson J Pearlstein T Londborg P | 2001 | Am J Psychiatry2001,158,12: | 1 |
| 19 | 查看详情显示文摘 | Lockhart T P Davidson F | | 0,,: | 1 |
| 20 | Inaetivation of Escherichia coli and Listeria innoeua in apple and carrot juices using high pressure homogenization and nisin 显示文摘 | Pathanibul P Taylor T M Davidson P M | 2009 | International Journal of Food Microbiology2009,129,: | 1 |