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| 1 | Paleomagnetic data from Early Cretaceous volcanic rocks of West Liaoning:Evidence for intracontinental rotation显示文摘Detailed rock magnetic studies of 55 lavas from Yixian and Fuxin area, West Liaoning, show the primary carriers of remanence to be pseudo-single domain ti-tanomagnetite. K/Ar dating indicates that the volcanic sequence spans 93 to 133 Ma. Stepwise thermal demagnetization successfully isolated well-defined characteristic magnetization (ChRM) in all lavas thermal-treated above 250℃ The mean paleodirections are D/I=5.9°/58.8° (α95 = 2.9°) and D/I =179.2°/-59.9° (α95 = 5.2°) for 27 normally magnetized flows and 28 reversibly magnetized flows, respectively. It indicates that since the Early Cretaceous there is no significant horizontal movement and rotation between the Yixian-Fuxin area and Eurasia. However, Korea Peninsula may have undergone a clockwise rotation of 33.9° relative to the Yixian-Fuxin area during the Cretaceous. On the basis of characteristics of hotspot origins (core-mantle boundary or upper mantle), the clockwise rotation of Korea Peninsula relative to Eurasia is assumed to be | ZHU Rixiang SHAO Ji’an PAN Yongxin SHI Ruiping SHI Guanghai LI Darning | 2002 | Chinese Science Bulletin2002，47，21： | 31 |
| 2 | Effects of Sc, Zr and Tion the microstructure and properties of Al alloys with high Mg content显示文摘The effects of trace Sc, Zr, and Ti on the microstructure and hardness of Al alloys with high Mg content (Al-6Mg, Al-8Mg, and Al-10Mg) were studied by optical microscope, scanning electron microscopy (SEM), transmission electron microscopy (TEM), and Brinell hardness. The grain size of the ascast alloys was refined by the addition of Sc and Zr, and it was further refined by the addition of Ti. With the same contents of Sc, Zr, and Ti, an increase in Mg content was beneficial to the refinement due to the solution of Mg into α-Al. The refined microstructures of the as-cast alloys were favorable for Brinell hardness. Addition of Sc, Zr, and Ti to the Al-10Mg alloy results in the improvement of peak hardness and it is about 45% higher than that of the Al-10Mg alloy, which is due to fine precipitations of Al3(Sc1-xZrx), Al3(Sc1-xTix), and Al3(Sc1-x-yZrxTiy). | WANG Xu CHEN Guoqin LI Bing WU Lianmei JIANG Darning | 2010 | Rare Metals2010，29，1： | 18 |
| 3 | Ubiquitylation of p62/sequestosome1 activates its autophagy receptor function and controls selective autophagy upon ubiquitin stress显示文摘在细胞的 ubiquitin (Ub ) 的改变动态平衡,作为 Ub 知道强调,展示并且影响处于多重条件的细胞的回答,然而,内在的机制不完全地被理解。这里,我们报导 autophagy 受体 p62/sequestosome-1 与结合酶, UBE2D2 和 UBE2D3 的 E2 Ub 交往。内长的 p62 在 Ub 动态平衡的 upregulation 期间经历 E2 依赖的 ubiquitylation,一个条件作为 Ub + 应力称为,那对由 bortezomib 的 Ub overexpression,热吃惊或延长 proteasomal 抑制内在,化学疗法的药。p62 的 Ubiquitylation 破坏 p62 的 UBA 领域的 dimerization,解放它的能力认出为选择 autophagy 的 polyubiquitylated 货物。我们进一步证明这机制可能为在 Ub + 压力条件之上的 autophagy 激活是批评的。机制的描述和在察觉到 Ub 应力并且控制选择 autophagy 的 p62 的规章的角色能帮助理解并且调制细胞的回答到许多内长、环境的挑战,潜在地对 autophagy 相关的病为治疗学的策略的发展打开一条新大街。 | Hong Peng Jiao Yang Guangyi Li Qing You Wen Han Tianrang Li Darning Gao Xiaoduo Xie Byung-Hoon Lee Juan Du Jian Hou Tao Zhang Hai Rao Ying Huang Qinrun Li Rong Zeng Lijian Hui Hongyan Wang Qin Xia Xuemin Zhang Yongning He Masaaki Komatsu Ivan Dikic Daniel Finley Ronggui Hu | 2017 | Cell Research2017，27，5： | 9 |
| 4 | K-Ar age of young volcanic rocks and excess argon——Binary mixing model and quantitative study of excess argon effect显示文摘A binary mixing model for excess argon is suggested in the note. According to thismodel and the data of excess argon component obtained in our experiment, a quantitative study of the effect of excess argon on real K-Ar age of young volcanic rocks is done. The result indicates that the effect of 5% excess argon component in samples on K-Ar age of the samples more than 2 Ma is less than 7.36% and can lead K-Ar age of 0.5 Ma samples to increase by 32.4%, while 1% excess argon component leads K-Ar age of 0.5 Ma samples to increase by 6.26%. Therefore, when pre-processed excess argon component is ≤1%, K-Ar age of the samples more than 0.5 Ma should be credible. On this basis we suggest a principal opinion for evaluation of previous K-Ar dating results and propose that the matrix is used to determine K-Ar age of young volcanic rocks. For the samples less than 0.2 Ma, in the case of high excess argon content, even if only 1% excess argon component exists in their matrix, it can also greatly affect their K-A | Darning Li Wenji Chen Qi Li | 2000 | Chinese Science Bulletin2000，45，7： | 4 |
| 5 | MicroRNA-150 aggravates H2O2-induced cardiac myocyte injury by down-regulating c-myb gene显示文摘MicroRNAs (miRNAs ) 是经由降级或他们的目标基因的翻译抑制在 post-transcriptional 规定起一个重要作用的非编码的 RNA 的一个班。MicroRNA-150 (miR-150 ) 在调整 B 和 T 淋巴细胞的发展起一个重要作用。尽管 miR-150 的 dysregulation 在人的心肌的梗塞被证实,很少响应反应的氧种类(ROS ) 关于 miR-150 的生物功能被知道在心脏的 myocytes 的调停的基因规定。用量的即时反向的抄写聚合酶链反应,我们证明 miR-150 的水平在在有氢过氧化物(H2O2 ) 的治疗以后的心脏的 myocytes 是起来调整的。在调停 H2O2 的基因规定识别 miR-150 的潜在的角色,我们调制了表示用 miR-150 禁止者的 miR-150 和 miR-150 模仿。结果证明 miR-150 的那 silencing 表情减少了导致 H2O2 的心脏的房间死亡和 apoptosis。在淋巴细胞, c-myb 是 miR-150 的一个直接目标。在心脏的 myocytes,我们发现 c-myb 也涉及 miR-150-mediated 导致 H2O2 的心脏的房间死亡。这些结果建议 miR-150 在心脏的 myocytes 参予调停 H2O2 的基因规定和功能的调整。MiR-150 可以在与 ROS 有关的心疾病起一个必要作用,例如心脏的肥大,心失败,心肌的梗塞,和心肌的 ischemia/reperfusion 损害。 | Xuebiao Li Minjian Kong Darning Jiang Jianfang Qian Qunjun Duan Aiqiang Dong | 2013 | Acta Biochimica et Biophysica Sinica2013，45，9： | 3 |
| 6 | Numerical method for solution of strongly coupled binary alloy solidification problems 显示文摘 | XU Darning LI Qingchun | 1991 | Numerical Heat Transfer Part A1991，20，2： | 1 |
| 7 | SPH modeling of droplet impact on solid boundary显示文摘 | Li Darning Bai Ling Li Lingling | 2014 | Transactions of Tianjin University2014，20，： | 1 |
| 8 | Adhering wear mechanism of cemented carbide cutter in the intervallic cutting of stainless steel显示文摘 | Fenglian Sun Zhenjia Li Darning Jiang | 1998 | Wear1998，214，： | 1 |
| 9 | Experimental Studies on a High Performance Compact Loop Heat Pipe With a Square Flat Evaporator 显示文摘 | LI ai WANG Darning Peterson O P | 2010 | Applied Thermal Engineering2010，30，： | 1 |
| 10 | Burning behavior and pyrolysis products of flame-retardant PET containing sulfur-containing aryl polyphosphonote 显示文摘 | Deng Li Wang Yuzhong Ban Darning | 2006 | J Anal Appl Pyrolysis2006，76，： | 1 |
| 11 | Variability of ex-treme precipitation over Yunnan Province, China 1960-2012 显示文摘 | Li Yungang He Darning Hu Jinming | 2015 | International Journal of Climatology2015，35，2： | 1 |
| 12 | The microstructural evolution of an Al-Zn-Mg-Cu alloy during homogenization显示文摘 | Xigang Fan Darning Jiang Qingchang Meng Zhong Li | 2006 | Materials Letters2006，，： | 1 |
| 13 | A Novel Approach to Construct Object-oriented System Dependence Graph and Algorithm Design 显示文摘 | Du Lin Xiao Guorong Li Darning | 2012 | Journal of Software2012，7，1： | 1 |
| 14 | Prophylaxis of tumor through oral administration of IL-12 GM-CSF gene carried by live attenuated salmonella显示文摘A live attenuated AraA autotrophic mutant of Salmonella typhimurium (SL3261) was used as carrier for eukaryotic expression vectors EGFPN1, pCMVmIL-12, pCMVWL-12, pCMVmGM-CSF and PCMVhGM-CSF and was administered orally to BALB/c and C57BL/6 mice. After 6 weeks, these mice were challenged with 4T1 and Lewis tumor cells respectively. GFP expression and gene integration could be detected in mice’s livers, spleens, intestines, kidneys and tumors. The serum level of cytokines increasedsignificantly in treated mice, so did the ratio of CD8+/CD4+,which resulted in the tumor regression and prolongation of the survival time of those mice. These researches laid an experimental foundation for the tumor gene therapy using live attenuated salmonella. | LI Yuhua CHEN Hui QUO Kunyuan XIE Yongmei WANG Feng XIE Kuangcheng HUANG Jiangsheng REN Darning | 2001 | Chinese Science Bulletin2001，46，13： | 1 |
| 15 | Remote Detection of Hydrocarbon Microseepage in a Loess Covered Area显示文摘Hydrocarbon microseepage can result in related near-surface mineral alterations.In this study,we evaluated the potential of detecting these alterations with field measured and satellite acquired hyperspectral data.Fourteen soil samples and reflectance spectra were collected in the Xifeng Oilfield,a loess covered area.Soil samples were analyzed in the laboratory for calcite,dolomite,kaolinite,illite,and mixedlayer illite/smectite content,and we processed reflectance spectra for continuum removal to derive clay and carbonate mineral absorption depth(H).High correlation between absorption depth and mineral content was shown for clay and mineral carbonate with field measured spectra.Based on the result for the field spectra,we proposed and tested a fast index based on the absorption depth of clay and carbonate minerals with a hyperspectral image of the area.The detected hydrocarbon microseepage anomalies matched well with those shown in the geological map. | Liang Zhao Darning Wang Shengbo Chen Lin Li Tianyu Zhang | 2020 | Journal of Earth Science2020，31，1： | 0 |
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