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| 1 | Effects of Sc, Zr and Tion the microstructure and properties of Al alloys with high Mg content显示文摘The effects of trace Sc, Zr, and Ti on the microstructure and hardness of Al alloys with high Mg content (Al-6Mg, Al-8Mg, and Al-10Mg) were studied by optical microscope, scanning electron microscopy (SEM), transmission electron microscopy (TEM), and Brinell hardness. The grain size of the ascast alloys was refined by the addition of Sc and Zr, and it was further refined by the addition of Ti. With the same contents of Sc, Zr, and Ti, an increase in Mg content was beneficial to the refinement due to the solution of Mg into α-Al. The refined microstructures of the as-cast alloys were favorable for Brinell hardness. Addition of Sc, Zr, and Ti to the Al-10Mg alloy results in the improvement of peak hardness and it is about 45% higher than that of the Al-10Mg alloy, which is due to fine precipitations of Al3(Sc1-xZrx), Al3(Sc1-xTix), and Al3(Sc1-x-yZrxTiy). | WANG Xu CHEN Guoqin LI Bing WU Lianmei JIANG Darning | 2010 | Rare Metals2010，29，1： | 18 |
| 2 | Ubiquitylation of p62/sequestosome1 activates its autophagy receptor function and controls selective autophagy upon ubiquitin stress显示文摘在细胞的 ubiquitin (Ub ) 的改变动态平衡,作为 Ub 知道强调,展示并且影响处于多重条件的细胞的回答,然而,内在的机制不完全地被理解。这里,我们报导 autophagy 受体 p62/sequestosome-1 与结合酶, UBE2D2 和 UBE2D3 的 E2 Ub 交往。内长的 p62 在 Ub 动态平衡的 upregulation 期间经历 E2 依赖的 ubiquitylation,一个条件作为 Ub + 应力称为,那对由 bortezomib 的 Ub overexpression,热吃惊或延长 proteasomal 抑制内在,化学疗法的药。p62 的 Ubiquitylation 破坏 p62 的 UBA 领域的 dimerization,解放它的能力认出为选择 autophagy 的 polyubiquitylated 货物。我们进一步证明这机制可能为在 Ub + 压力条件之上的 autophagy 激活是批评的。机制的描述和在察觉到 Ub 应力并且控制选择 autophagy 的 p62 的规章的角色能帮助理解并且调制细胞的回答到许多内长、环境的挑战,潜在地对 autophagy 相关的病为治疗学的策略的发展打开一条新大街。 | Hong Peng Jiao Yang Guangyi Li Qing You Wen Han Tianrang Li Darning Gao Xiaoduo Xie Byung-Hoon Lee Juan Du Jian Hou Tao Zhang Hai Rao Ying Huang Qinrun Li Rong Zeng Lijian Hui Hongyan Wang Qin Xia Xuemin Zhang Yongning He Masaaki Komatsu Ivan Dikic Daniel Finley Ronggui Hu | 2017 | Cell Research2017，27，5： | 9 |
| 3 | Expression, purification of a synthetic fuse-protein-TSF from PF4 and TSP1 fragments and its effect on angio-genesis and tumor growth显示文摘Sequences encoding PF4 (58-70) and TSP1 (429-459) were linked to yield a single gene TSF which encodes the fuse-protein of TSF. The gene was cloned into a pGEX-2T expression vector to generate a protein GST-TSF, which was strongly expressed in E. coli. The purified GST-TSF was degraded with thrombin to generate the protein TSF. With the methods of MTT and wound repair assay, the effects of TSF on the proliferation and migration of EC were detected, respectively. The results showed that TSF significantly suppressed BAEC proliferation and migration in a dose-dependent manner. The fuse protein GST-TSF, and the peptides PF4 (58-70) and TSP1 (429-459) also inhibited BAEC proliferation and migration, respectively, but their inhibition rates were not as high as TSF. Using the CAM assay, it was shown that TSF, GST-TSF, PF4 (58-70) and TSP1 (429-459) inhibited angiogenesis in chick CAM potentially, the effect of TSF was the highest. In vivo, the growth of Lewis lung carcinoma was potently inhibited by TSF | SHEN Xianrong JI Dongmei HU Youqing JIA Fuxing DENG Xinxian WANG Ling CHU Zhiyong JIANG Dingwen LEI Chengxiang HUANG Jiansheng HU Xinran REN Darning | 2001 | Chinese Science Bulletin2001，46，24： | 2 |
| 4 | Determining the effects of microwave heating on the ordered structures of rice starch by NMR 显示文摘 | Darning Fan Wenrui Ma Liyun Wang | 2013 | Carbohydrate Polymers2013，92，2： | 1 |
| 5 | The effect of the second phase inversion on microstructures in phase inversion EVAL membranes显示文摘 | Young Taihomg Wang Darning Hsieh Chihchen | 1998 | Journal of Membrane Science1998，146，： | 1 |
| 6 | A novel nondripping oligomeric flame retardant for polyethylene terephthalate 显示文摘 | Ban Darning Wang Yuzhong Yang Bing | 2004 | Eur Polym J2004，40，8： | 1 |
| 7 | Effect of Mg content on the mechanical properties and microstructure of Gf/Al composite显示文摘 | WANG Xu JIANG Darning WU Gaohui | 2008 | Materials Science and Engineering A2008，497，12： | 1 |
| 8 | A Novel Nondripping Oligomeric Flame Retardant for Polyethylene Terephthalate 显示文摘 | Ban Darning Wang Yuzhong Yang Bing | 2004 | Europ Polym J2004，40，8： | 1 |
| 9 | Com- parison of the tribological properties of an ion sulfurized coating and a plasma sprayed FeS coating 显示文摘 | Wang Haidou Zhuang Darning Wang Kunlin | 2003 | Materials Science and Engineering:A2003，357，： | 1 |
| 10 | A novel phosphorus-containing polymer as a highly effective flame retardant 显示文摘 | Chang Yulong Wang Yuzhong Ban Darning | 2004 | nacromolecular Materials and Engineering2004，289，8： | 1 |
| 11 | The comparison on tribological properties of ion sulfuration steels under oil lubrication显示文摘 | WANG Haidou ZHUANG Darning WANG Kunlin | 2003 | Materials Letters2003，57，： | 1 |
| 12 | A novel non-dripping oligomeric flame retardant for polyethylene terephthalate显示文摘 | Ban Darning Wang Yuzhong Yang Bing | 2004 | European Polymer Journal2004，40，： | 1 |
| 13 | An O(n^2) algorithm for signed translocation 显示文摘 | Wang Lusheng Zhu Darning Liu Xiaowen | 2005 | Journal of Computer and System Sciences2005，70，3： | 1 |
| 14 | Comparison of 'the tribological properties of an ion sulfurized coatingand a plasma sprayed FeS coating 显示文摘 | Wang Haidou Zhuang Darning Wang Kunlin | 2003 | Materials Science and Engineering2003，357，： | 1 |
| 15 | Experimental Studies on a High Performance Compact Loop Heat Pipe With a Square Flat Evaporator 显示文摘 | LI ai WANG Darning Peterson O P | 2010 | Applied Thermal Engineering2010，30，： | 1 |
| 16 | Burning behavior and pyrolysis products of flame-retardant PET containing sulfur-containing aryl polyphosphonote 显示文摘 | Deng Li Wang Yuzhong Ban Darning | 2006 | J Anal Appl Pyrolysis2006，76，： | 1 |
| 17 | Formationmechanism of the macrovoids induced by surfactant additives显示文摘 | Wang Darning Lin Fungching Wu Tiantsair | 1998 | Journal of Membrane Science1998，142，2： | 1 |
| 18 | Prophylaxis of tumor through oral administration of IL-12 GM-CSF gene carried by live attenuated salmonella显示文摘A live attenuated AraA autotrophic mutant of Salmonella typhimurium (SL3261) was used as carrier for eukaryotic expression vectors EGFPN1, pCMVmIL-12, pCMVWL-12, pCMVmGM-CSF and PCMVhGM-CSF and was administered orally to BALB/c and C57BL/6 mice. After 6 weeks, these mice were challenged with 4T1 and Lewis tumor cells respectively. GFP expression and gene integration could be detected in mice’s livers, spleens, intestines, kidneys and tumors. The serum level of cytokines increasedsignificantly in treated mice, so did the ratio of CD8+/CD4+,which resulted in the tumor regression and prolongation of the survival time of those mice. These researches laid an experimental foundation for the tumor gene therapy using live attenuated salmonella. | LI Yuhua CHEN Hui QUO Kunyuan XIE Yongmei WANG Feng XIE Kuangcheng HUANG Jiangsheng REN Darning | 2001 | Chinese Science Bulletin2001，46，13： | 1 |
| 19 | Remote Detection of Hydrocarbon Microseepage in a Loess Covered Area显示文摘Hydrocarbon microseepage can result in related near-surface mineral alterations.In this study,we evaluated the potential of detecting these alterations with field measured and satellite acquired hyperspectral data.Fourteen soil samples and reflectance spectra were collected in the Xifeng Oilfield,a loess covered area.Soil samples were analyzed in the laboratory for calcite,dolomite,kaolinite,illite,and mixedlayer illite/smectite content,and we processed reflectance spectra for continuum removal to derive clay and carbonate mineral absorption depth(H).High correlation between absorption depth and mineral content was shown for clay and mineral carbonate with field measured spectra.Based on the result for the field spectra,we proposed and tested a fast index based on the absorption depth of clay and carbonate minerals with a hyperspectral image of the area.The detected hydrocarbon microseepage anomalies matched well with those shown in the geological map. | Liang Zhao Darning Wang Shengbo Chen Lin Li Tianyu Zhang | 2020 | Journal of Earth Science2020，31，1： | 0 |
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