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| 1 | The Chromosome-Level Reference Genome of Tea Tree Unveils Recent Bursts of Nonautonomous LTR Retrotransposons in Driving Genome Size Evolution显示文摘Dear Editor,The tea tree Camellia sinensis,a member of the genus Camellia in the Theaceae family,includes two major cultivated varieties,C.sinensis var.assamica(CSA\Assam type)and C.sinensis var.sinensis(CSS;Chinese type)(Ming and Bartholomew,2007).Due to the high economic importance of the tea tree,considerable efforts have been made to explore genetic basis of the biosynthesis of natural metabolites that determine health benefits and diverse tea flavors(Shi et al.,2011;Li et al.,2011;Li et al.,2015;Xia et aL,2017;Liu et al.,2019). | Qun-Jie Zhang Wei L i Kui Li Hong Nan Cong Shi Yun Zhang Zhang-Yan Dai Yang-Lei Lin Xiao-Lan Yang Yan Tong Dan Zhang Cui Lu Li-Ying Feng Chen-Feng Wang Xiao-Xin Liu Jian-An Huang Wen-Kai Jiang Xing-Hua Wang Xing-Cai Zhang Evan E.Eichler Zhong-Hua Liu and Li-Zhi Gao | 2020 | Molecular Plant2020，13，7： | 27 |
| 2 | Prognostic evaluation of postoperative adjuvant therapy for operable cervical cancer:10 years'experience of National Cancer Center in China显示文摘Objective: The aim of this study was to investigate the prognostic factors and to evaluate the impact of adjuvant therapy on clinical outcome for early-stage cervical cancer.Methods: The clinical-pathological data of all 1,335 patients with the International Federation of Gynecology and Obstetrics(FIGO) Ib–IIa cervical cancer treated with primary radical surgery at the Chinese National Cancer Center between May 2007 and Dec 2013 were retrospectively reviewed.The median follow-up was 70 months.Results: Of all the patients,61.6% of the cases received adjuvant therapy,with 5-year disease-free survival(DFS)of 92.1% and 5-year overall survival(OS) of 95.0%.In multivariate analysis,differentiation of G3(P<0.05),lymph node metastasis(LNM,P<0.05) and lymphovascular space invasion(LVSI,P<0.05) were independent predictors for OS,while LNM(P<0.05),deep stroma invasion(DSI,P<0.05) and LVSI(P<0.05) were independent factors for DFS.The samples were stratified by histologic type,and cervical squamous cell carcinoma(SCC) was found to share the same independent factors except for differentiation of OS.As to patients with cervical adenocarcinoma/adenosquamous carcinoma(AC/ASC),differentiation was the independent predictor of OS(P<0.05); and LVSI of DFS(P<0.05).Of 236 patients with high-risk factors,there was no significant difference in survival between concurrent chemoradiotherapy(CCRT,n=195),radiotherapy(RT,n=24),and chemotherapy(CT,n=17).Among the 190 patients with LNM who underwent CCRT,124 cases showed improved DFS after sequential CT(P=0.118),with a recurrence rate decrease of 14%,though the difference was not statistically significant.Patients with single intermediate-risk factors like DSI or LVSI were found to partially benefit from adjuvant therapy,but the difference was not statistically significant.Conclusions: LNM,LVSI,DSI and differentiation were found to be independent prognostic factors for operable cervical cancer.Aggressive postoperative adjuvant therapy based on single risk factors in Chinese National Cancer Center could benefit survival.CCRT+CT outperformed CCRT in high-risk patients.For patients with single non-high-risk factor,the role of adjuvant therapy needs to be further discussed. | Tong Shu Dan Zhao Bin Li Yating Wang Shuanghuan Liu Pingping Li Jing Zuo Ping Ba i RongZhang Lingying Wu | 2017 | Chinese Journal of Cancer Research2017，29，6： | 12 |
| 3 | Teenagers’Sexual Behavior in Sweden, Europe显示文摘Objective To investigate the development of sexuality from early to late adolescence,and to compare girls and boys of different agesMethods A cross sectional survey in all schools was performed covering all pupilsbetween 13 and 18 years of age that were in school when the survey was conducted. Avalidated instrument, Q90, created for use in teenagers was distributed in the class-rooms to 3 216 teenagers. Q90 covers 30 questions about body development andsexual behavior. Non-response was insignificant (n=19; 0.6%).Results Pubertal development was considered “early” or “late” by about 50% ofboth boys and girls. Eighty percent of the 13 to 15 years old boys and girls had had aromance and 30% had experience of sexual cuddling (petting), while significantlymore girls than boys had sexual intercourse (18% vs 13%; odds ratio 1.5, 95% CI1.1-1.9). The difference between girls and boys remained in those being 16-18 yearsold, where 63% of the girls and 53% of the boys (odds ratio 1.5, 95% CI 1.2-1.9)admitted having intercourse. Mean age at first intercourse was 14.9 and 15 years,respectively. At 16-18 years of age, 23% of the sexually active girls, as compared with25% of the boys estimated that they had had 6 or more sexual partners. About 30% ofthe adolescents, irrespective of age and gender, did not use contraceptives at theirfirst and latest intercourse. Eight percent of the older girls had been pregnant, andthey had an increased history of sexually transmitted infections, as compared withthe boys (6.2% vs 2.7%; odds ratio 2.4, 95% CI 1.2-5.0).Conclusion Exploring sexuality and experimentation is a normal behavior inadolescence. The results of this study, however, indicate that there are substantialgroups of teenagers who practice sexual risk-taking. In addition to general sexualeducation, programs should also be directed to define sexual risks and its consequences. | Lars I Holmberg Dan Hellberg | 2005 | Journal of Reproduction and Contraception2005，16，3： | 2 |
| 4 | Cloning, expression, Charac- terization, and nucleophile identification of family 3, Aspergillus niger beta-glucosidase显示文摘 | Dan S Marton I Dekcl M | 2000 | The Journal of Biological Chemistry2000，275，： | 1 |
| 5 | Effect of addition fluoroethers to organic solvents for lithium ion secondary batteries 显示文摘 | NAKAJIMA T DAN K I KOH M | 2001 | Journal of Fluorine Chemistry2001，111，： | 1 |
| 6 | Precise Global Collision Detection in Multi-axis NC-machining显示文摘 | Oleg I Gershon E Dan H | | 0，，09： | 1 |
| 7 | Rapid synthesis of nanocrystalline TiO2/SnO2 binary oxides and their photoinduced decomposition of methyl orange显示文摘 | YANG JUAN DAN L I WANG XIN | 2002 | Journal of Solid State Chemistry2002，165，1： | 1 |
| 8 | Acute moderate exercise elicits increased dorsolateral prefrontal activation and improves cognitive performance with Stroop test显示文摘 | YANAGISAWA H DAN I TSUZUKI D | 2010 | Neuroimage2010，50，4： | 1 |
| 9 | Control of an interconnected power system:a time delay approach显示文摘 | Dan I Aaron F S Jean-Michel Dion | 2002 | IMA Journal of Mathematical Control and Information2002，19，1： | 1 |
| 10 | Immunobiology of endometriosis 显示文摘 | Dan I Lebovic M D M A Michael D Mueller M D Robert N Taylor M D | 2001 | Fertil Steril2001，75，1： | 1 |
| 11 | Acute moder- ate exercise elicits increased dorsolateral prefrontal activation and improves cognitive performance with Stroop test显示文摘 | YANAGISAWA H DAN I TSUZUKI D | 2010 | Neuroimage2010，50，4： | 1 |
| 12 | Air Distribution for Comfort and IAQ显示文摘 | DAN I H | 1998 | Heating Piping and Air Condition1998，，5： | 1 |
| 13 | Chatacterisation of Hungarian porcine circovirus 2 genomes associated with PMWS and PDNS cases显示文摘 | DAN A MOLNAR T BIKSI I | 2003 | Acta Vet Hung2003，51，4： | 1 |
| 14 | Pathogenic coloniza- tion of the stomach in enterally fed elderly patients compa- ring percutaneous endoscopic gastrostomy with nasogastric tube显示文摘 | Segal R Dan M Porgoreliuk I | 2006 | J Am Gcriatre Soc2006，54，13： | 1 |
| 15 | Induction of systemic acquired resistance in cotton by BTH has a negligible effect on phytophagous insects显示文摘 | Moshe I Hamed D Dan G | 2001 | Entomplogia Experimentalis et Applicata2001，99，： | 1 |
| 16 | Immunobiology of endometriosis显示文摘 | Dan I Lebovic MD Mueller MD | 2001 | Fertil Steril2001，75，1： | 1 |
| 17 | Antinutrophil cytoplastic antibodies in patients with systemic lupus erythematosus: prevalence, antigen specificity, and clinical associations 显示文摘 | Manolova I Dan CM Halacheva K | 2001 | Rheumtol Int2001，20，： | 1 |
| 18 | Unbalanced magnetic pull due to asymmetry and low-level static rotor eccentricity in fractional-slot brushless permanent-magnet motors with surface-magnet and consequent-pole rotors显示文摘 | DAVID G D MIRCEA P DAN M I | | 0，，07： | 1 |
| 19 | Geometrically nonlinear finite element reliability analysis of structural systems(Ⅰ):theory显示文摘 | KIYOHIRO I DAN M F | 2000 | Computers and Structures2000，77，6： | 1 |
| 20 | 10/20, 10/10, and 10/5 Systems Revisited: Their Validity as Relative Head-Surface Based Positioning Systeins显示文摘 | Jurcak V Tsuzuki D Dan I | 2007 | Neuroimage2007，34，4： | 1 |
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