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| 1 | A new iridoid glycoside from Gardenia jasminoides显示文摘新 iridoid glycoside, 6 ′ - O-sinapoylgeniposide,从栀子 jasminoides 埃利斯被孤立,它的结构根据 1D 和 2D NMR 被阐明, HR-ESI-MS 技术。 | Xiao Qin Zhou Zhi Ming Bi Ping Li Dan Tang Hal Xia Cai | 2007 | Chinese Chemical Letters2007，18，10： | 10 |
| 2 | Two new saponins from the aerial part of Astragalus membranaceus var. mongholicus显示文摘Two new saponins named mongholicoside A (1) and mongholicoside B (2) were isolated from the aerial part of Astragalus membranaceus var. mongholicus. Their structures were determined by 1D and 2D NMR, ESI-MS techniques and chemical methods. | Qing Tao Yu Ping Li Zhi Ming Bi Jun Luo Xiao Dan Gao | 2007 | Chinese Chemical Letters2007，18，5： | 7 |
| 3 | ZnO-MWCNTs/Nafion inorganic-organic composite film:Preparation and application in bioelectrochemistry of hemoglobin显示文摘Multi-walled carbon nanotubes(MWCNTs) were coated with ZnO by a hydrothermal method.The resulting nanocomposites were mixed with the Nafion solution to form a composite matrix for the fabrication of hemoglobin(Hb) biosensor.To prevent the leak of Hb molecules of the biosensor,silica sol-gel film was coated on the surface of the Hb/ZnO-MWCNTs/Nafion electrode.The silica sol-gel/Hb/ZnO-MWCNTs/Nafion film exhibited a pair of well-defined,quasi-reversible redox peaks.This biosensor showed excellent electrocatalytic activity to H_2O_2.The sensitivity and apparent Michaelis-Menten constant of this Hb biosensor to H_2O_2 were 1.31 A/(M cm^2) and 82.8μmol/L,respectively,which indicated that Hb had high affinity to H_2O_2. | Wei Ma Wei Song Dan Bi Tian | 2009 | Chinese Chemical Letters2009，20，3： | 6 |
| 4 | Assessment of Temperature Extremes in China Using RegCM4 and WRF显示文摘This study assesses the performance of temperature extremes over China in two regional climate models(RCMs),RegCM4 and WRF, driven by the ECMWF's 20 th century reanalysis. Based on the advice of the Expert Team on Climate Change Detection and Indices(ETCCDI), 12 extreme temperature indices(i.e., TXx, TXn, TNx, TNn, TX90 p, TN90 p,TX10 p, TN10 p WSDI, ID, FD, and CSDI) are derived from the simulations of two RCMs and compared with those from the daily station-based observational data for the period 1981–2010. Overall, the two RCMs demonstrate satisfactory capability in representing the spatiotemporal distribution of the extreme indices over most regions. RegCM performs better than WRF in reproducing the mean temperature extremes, especially over the Tibetan Plateau(TP). Moreover, both models capture well the decreasing trends in ID, FD, CSDI, TX10 p, and TN10 p, and the increasing trends in TXx, TXn, TNx, TNn, WSDI, TX90 p,and TN90 p, over China. Compared with observation, RegCM tends to underestimate the trends of temperature extremes,while WRF tends to overestimate them over the TP. For instance, the linear trends of TXx over the TP from observation,RegCM, and WRF are 0.53?C(10 yr)^(-1), 0.44?C(10 yr)^(-1), and 0.75?C(10 yr)^(-1), respectively. However, WRF performs better than RegCM in reproducing the interannual variability of the extreme-temperature indices. Our findings are helpful towards improving our understanding of the physical realism of RCMs in terms of different time scales, thus enabling us in future work to address the sources of model biases. | Xianghui KONG Aihui WANG Xunqiang BI Dan WANG | 2019 | Advances in Atmospheric Sciences2019，36，4： | 5 |
| 5 | Rapid and sensitive determination of fatty acids in edible oil by liquid chromatography-electrospray ionization tandem mass spectrometry显示文摘A sensitive and robust on-line LC/MS method was developed for quantitative determination of linoleic acid,docosahexaenoic acid and docosanoic acid from edible oil samples.The oil samples were dissolved in chloroform-isopropyl alcohol(20:80,v:v)solution and the three fatty acids were separated by HPLC with a C4 column using 10 mmol/L ammonium acetate-isopropyl alcohol-acetonitrile(20:40:40,v:v:v)mobile phase in isocratic elution.Electrospray ionization mass spectrometry with the selected ion recording monitoring was used to detect and quantify the fatty acid.The calibration curves were linear in the range of 10.00–5000 pg/mL for linoleic acid and docosanoic acid,and 1.000–500.0 pg/mL for docosahexaenoic acid.The limit of detection was 2.0 pg/mL for linoleic acid,3.0 pg/mL for docosanoic acid,and 0.20 pg/mL for docosahexaenoic acid.The results showed that the method described in this paper could be utilized for rapid determination of three fatty acids at picogram levels in edible oils. | BI Xin JIN YiBao LI ShangFu GAO Dan JIANG YuYang LIU HongXia | 2014 | Science China Chemistry2014，57，3： | 4 |
| 6 | A comparison of surgical efficacy between a 1.8-mm microincision and 3.2-mm and 5.5-mm incisions for phacoemulsification显示文摘Phacoemulsification is a commonly used surgical method in cataract surgery. This paper observes and compares the surgical efficacy of three incisions of different length for phacoemulsification to identify the optimal method for cataract surgery. Ninety patients were enrolled in the present study and divided into three groups. The 1.8-mm group received Bausch & Lomb MI60 foldable intraocular lens(IOL) implantation(n=30), 3.2-mm group received Bausch & Lomb Akreos AO foldable lens implantation(n=30), and 5.5-mm group received Alcon TYPE 05 rigid IOL implantation(n=30). Visual acuity, Oculyzer-based anterior segment analysis, and corneal endothelial cell count before surgery, and 3, 7, 30, and 90 d after surgery were recorded and compared. Pseudophakic accommodation three days, one week, one month, and three months after surgery was determined. Intraoperative ultrasound time and ultrasonic energy were recorded. It was finally concluded that for phacoemulsification with the same phaco tip, a 1.8-mm microincision can lead to quicker recovery of visual acuity, more stable astigmatism, and higher pseudophakic accommodation than conventional incision. | E Song Xin Li Ming-Chao Bi Hua Ren Dan Wang Zhi-Hua Cui Wei Yang Hui Shi Ya-Bin Sun | 2018 | International Journal of Ophthalmology(English edition)2018，11，3： | 4 |
| 7 | Decoding lithium batteries through advanced in situ characterization techniques显示文摘Given the energy demands of the electromobility market,the energy density and safety of lithium batteries(LBs)need to be improved,whereas its cost needs to be decreased.For the enhanced performance and decreased cost,more suitable electrode and electrolyte materials should be developed based on the improved understanding of the degradation mechanisms and structure–performance correlation in the LB system.Thus,various in situ characterization technologies have been developed during the past decades,providing abundant guidelines on the design of electrode and electrolyte materials.Here we first review the progress of in situ characterization of LBs and emphasize the feature of the multi-model coupling of different characterization techniques.Then,we systematically discuss how in situ characterization technologies reveal the electrochemical processes and fundamental mechanisms of different electrode systems based on representative electrode materials and electrolyte components.Finally,we discuss the current challenges,future opportunities,and possible directions to promote in situ characterization technologies for further improvement of the battery performance. | Mei Yang Ruyi Bi Jiangyan Wang Ranbo Yu Dan Wang | 2022 | International Journal of Minerals,Metallurgy and Materials2022，29，5： | 4 |
| 8 | A selective voltammetric detection for dopamine using poly(gallic acid) film modified electrode显示文摘The electrochemistry behavior of dopamine was investigated by cyclic voltammetry and differential pulse voltammetry at a poly (gallic acid) film modified glassy carbon electrode.Two electrons and two protons participated in the diffusion-controlled electrocatalytic oxidation of dopamine with a diffusion coefficient of 2.186×10^(-5) cm^2/s.The interference of ascorbic acid with the determination of dopamine could be efficiently eliminated.This work provided a simple approach to selectively and sensitively... | Song, Wei Chen, Yu Xu, Juan Tian, Dan Bi | 2010 | Chinese Chemical Letters2010，21，3： | 3 |
| 9 | Rapid detection of intestinal pathogens in fecal samples by an improved reverse dot blot method显示文摘AIM:To develop a new, rapid and accurate reverse dot blot(RDB) method for the detection of intestinal pathogens in fecal samples.METHODS:The 12 intestinal pathogens tested were Salmonella spp., Brucella spp., Escherichia coli O157:H7, Clostridium botulinum , Bacillus cereus , Clostridium perfringens , Vibrio parahaemolyticus , Shigella spp., Yersinia enterocolitica, Vibrio cholerae, Listeria monocytogenes and Staphylococcus aureus.The two universal primers were designed to amplify two variable regions of bacterial 16S and 23S rDNA genes from all of the 12 bacterial species tested.Five hundred and forty fecal samples from the diarrhea patients were detected using the improved RDB assay.RESULTS:The methods could identify the 12 intestinal pathogens specifi cally, and the detection limit was as low as 103 CFUs.The consistent detection rate of the improved RDB assay compared with the traditional culture method was up to 88.75%.CONCLUSION:The hybridization results indicated that the improved RDB assay developed was a reliable method for the detection of intestinal pathogen in fecal samples. | Jian-Ming Xing Su Zhang Ying Du Dan Bi Li-Hui Yao | 2009 | World Journal of Gastroenterology2009，15，20： | 3 |
| 10 | Syntheses and Liquid Crystal Properties of New Rare Earth Sandwich Type Heteropoly Compounds显示文摘 | BI Li hua \{**\}, LIU Jing hua *** , WANG En bo **** , HUANG Ru dan YU Yong zhang and WU Ping song (Department of Chemistry, Northeast Normal University, Changchun 130024, P.R. China) (Received March 29, 1999) | 1999 | Chemical Research in Chinese Universities1999，15，4： | 2 |
| 11 | Effect of endothelial progenitor cells derived from human umbilical cord blood on oxygen-induced retinopathy in mice by intravitreal transplantation显示文摘·AIM: To investigate the effect of endothelial progenitor cells(EPCs) labeled by carboxy fluorescein diacetate succinimidyl ester(CFSE) on murine oxygen-induced retinopathy(OIR) by intravitreal transplantation.·METHODS: After isolated from human umbilical cord blood mononuclear cells, EPCs were cultivated and then labeled with CFSE in vitro. C57BL/6J mice were placed to75% hyperoxia chamber from P7 to P12 to establish OIR model. At P12, OIR mice were intravitreally injected with1 μL suspension contained 2×105EPCs(EPCs group) or isometric phosphate buffered saline(PBS group). The contralateral eye of each mice received no injection(OIR group). Evans blue angiography and frozen section were examined to track the labeled cells in OIR group at P15 and P19. Using retina paraffin sections and adenosinediphos phatase staining at P12 and P19, the effect of EPCs on OIR mice was evaluated quantitatively and qualitatively.· RESULTS: The retinas from EPCs group with less non-perfusion area and fewer peripheral tufts wereobserved at P19, comparing with that from PBS or OIR group. The retinopathy in EPCs group receded earlier with less non-ganglion cells and neovascular nuclei,together with relatively regular distribution. The counts of the neovascular nuclei at P19 were reduced by 44% or45%, compared with those of OIR group or PBS group respectively. Three days after EPCs injection, a large number of EPCs appeared in the vitreous cavity and adhered to the retinal surface. While at one week, the cells gathered between the internal plexiform layer and the inner limiting membrane, and some EPCs appeared in retinal vessels.·CONCLUSION: EPCs transplantation can participate in the reparative procedure of the neovascularization in OIR. | Dan Wang Bo Zhang Hui Shi Wei Yang Ming-Chao Bi Xiang-Fu Song Chen Zhang Jian-Hui Cheng Ji-Long Hao E Song | 2016 | International Journal of Ophthalmology(English edition)2016，9，11： | 2 |
| 12 | Safety and immunogenicity of human papillomavirus-16/18 AS04-adjuvanted vaccine in healthy Chinese females aged 15 to 45 years:a phase Ⅰ trial显示文摘Globally,about 70% of cervical cancers are associated with human papillomavirus (HPV)-16 or HPV-18 infection.A meta-analysis of epidemiologic studies in China showed that HPV was present in 98% of cervical cancer samples.The HPV-16/18 AS04-adjuvanted vaccine Cervarix has shown a high level of protection against HPV-16/18 infections and associated cervical lesions.This phase Ⅰ trial (NCT00549900) assessed the safety,tolerability,and immunogenicity of the vaccine in Chinese.Thirty healthy Chinese females,aged 15 to 45 years with a median age of 29.5 years,received three doses of Cervarix in Months 0,1,and 6.Safety was assessed via recording solicited local and systemic symptoms within 7 days and unsolicited symptoms within 30 days after each vaccination.Serious adverse events,new onset of chronic diseases,and other medically significant conditions were recorded throughout this trial.As an exploratory objective,HPV-16/18 antibody titers were determined by enzyme-linked immunosorbent assay in serum samples collected in Months 0 and 7.Pain at the injection site was the most frequently reported local symptom.Two subjects reported medically significant adverse events.Both cases were assessed as unrelated to vaccination by the investigator.In Month 7,100% seroconversion was observed for both anti-HPV-16 and anti-HPV-18 with high geometric mean antibody titers.HPV-16/18 AS04-adjuvanted vaccine,evaluated for the first time in Chinese females,was generally well tolerated and immunogenic,as previously shown in global studies. | Feng-Cai Zhu Chang-Gui Li Hong-Xing Pan Yi-Ju Zhang Dan Bi Hai-Wen Tang Sanjoy Datta | 2011 | Chinese Journal of Cancer2011，30，8： | 2 |
| 13 | Kinetic Characteristics of Neutralizing Antibody Responses Vary among Patients with COVID-19显示文摘Objective The coronavirus disease 2019(COVID-19) pandemic continues to present a major challenge to public health. Vaccine development requires an understanding of the kinetics of neutralizing antibody(NAb) responses to severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).Methods In total, 605 serum samples from 125 COVID-19 patients(from January 1 to March 14, 2020)varying in age, sex, severity of symptoms, and presence of underlying diseases were collected, and antibody titers were measured using a micro-neutralization assay with wild-type SARS-CoV-2.Results NAbs were detectable approximately 10 days post-onset(dpo) of symptoms and peaked at approximately 20 dpo. The NAb levels were slightly higher in young males and severe cases, while no significant difference was observed for the other classifications. In follow-up cases, the NAb titer had increased or stabilized in 18 cases, whereas it had decreased in 26 cases, and in one case NAbs were undetectable at the end of our observation. Although a decreasing trend in NAb titer was observed in many cases, the NAb level was generally still protective.Conclusion We demonstrated that NAb levels vary among all categories of COVID-19 patients. Longterm studies are needed to determine the longevity and protective efficiency of NAbs induced by SARS-CoV-2. | LI Ling Hua TU Hong Wei LIANG Dan WEN Chun Yan LI An An LIN Wei Yin HU Ke Qi HONG Wen Shan LI Yue Ping SU Juan ZHAO San Tao LI Wei YUAN Run Yu ZHOU Ping Ping HU Feng Yu TANG Xiao Ping KE Chang Wen KE Bi Xia CAI Wei Ping | 2021 | Biomedical and Environmental Sciences2021，34，12： | 1 |
| 14 | Controlling the false discovery rate in behavior genetics research显示文摘 | Yoav Bi Dan D Greg E Neri K Ilan G | 2001 | Behavioural Brain Research2001，125，1： | 1 |
| 15 | The surge-like eruption of a miniature filament显示文摘We report on the rare eruption of a miniature Hα filament that took the form of a surge. The filament first underwent a full development within 46 min and then began to erupt 9 min later, followed by a compact, impulsive X-ray class M2.2 flare with a two-ribbon nature only at the early eruption phase. During the eruption, its top rose, whereas the two legs remained rooted in the chromosphere and showed little swelling perpendicular to the rising direction. This led to a surge-like eruption with a narrow angular extent. Similar to the recent observations for standard and blowout X- ray jets by Moore et al., we thus define it as a 'blowout Hα surge.' Furthermore, our observations showed that the eruption was associated with (1) a coronal mass ejection guided by a pre-existing streamer, (2) abrupt, significant, and persistent changes in the photospheric magnetic field around the filament, and (3) a sudden disappearance of a small pore. These observations thus provide evidence that a blowout surge is a small- scale version of a large-scale filament eruption in many aspects. Our observations further suggest that at least part of the Hα surges belong to blowout-type cases, and the exact distinction between the standard and blowout Hα surges is important in understanding their different origins and associated eruptive phenomena. | Jia-Yan Yang Yun-Chun Jiang Dan Yang Yi Bi Bo Yang Rui-Sheng Zheng Jun-Chao Hong | 2012 | Research in Astronomy and Astrophysics2012，12，3： | 1 |
| 16 | High performance Au/Ag core/shell bipyramids for determination of thiram based on surface‐enhanced Raman scattering显示文摘 | Xia Zheng Yanhua Chen Yang Chen Ning Bi Haibo Qi Meihong Qin Dan Song Hanqi Zhang Yuan Tian | 2012 | J Raman Spectrosc2012，，10： | 1 |
| 17 | Overexpression of YKL-40 is an independent prognostic marker in gastric cancer显示文摘 | Jiong Bi Sze-Hang Lau Zi-Li Lv Dan Xie Wen Li Ying-Rong Lai Jue-Min Zhong Hui-qun Wu Qiao Su Yu-long He Wen-Hua Zhan Jian-Ming Wen Xin-Yuan Guan | 2009 | Human Pathology2009，，： | 1 |
| 18 | Rational syntheses, characterization, crystal structure, and replacement reactions of coordinated water molecules of ^10- (M = Cd, Co, Cu, Fe, Mn, Ni or Zn) 显示文摘 | BI Li Hua HUANG Ru Dan PENG Jun | 2001 | J Chem Soc: Dalton Trans2001，，： | 1 |
| 19 | Third generation biosensor based on myoglobin-TiO_2/MWCNTs modified glassy carbon electrode显示文摘TiO2 nanoparticles 在由热水的免职的多围的碳 nanotubes 上是同类地涂的,鉴于它的高 biocompatibility 和大表面,这 nanocomposite 可以是为肌球素固定的有希望的材料。与 Mb-TiO2/MWCNTs 电影修改的玻璃质的碳电极展出了一双明确、稳定、将近可逆的周期 voltammetric 山峰。在 Mb 和电极表面之间的电子转移, 3.08 s 的 K ? 1,极大地在 TiO2/MWCNTs 电影被便于。氢过氧化物的 electrocatalytic 减小被学习,明显的 Michaelis 鈥揗e nten 常数被计算是 83.10 渭 m ol/L,它在 TiO2/MWCNTs 电影显示出 Mb 的一项大催化活动到 H2O2。 | Lei Zhang Dan Bi Tian Jun Jie Zhu | 2008 | Chinese Chemical Letters2008，19，8： | 1 |
| 20 | Development of a UFLC–MS/MS method for simultaneous determination of six lignans of Schisandra chinensis (Turcz.) Baill. in rat plasma and its application to a comparative pharmacokinetic study in normal and insomnic rats显示文摘 | Binbin Wei Qing Li Dan Su Ronghua Fan Longshan Zhao Lulu Geng Bosai He Xiaohui Chen Ying Jia Kaishun Bi | 2013 | Journal of Pharmaceutical and Biomedical Analysis2013，，： | 1 |
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