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30篇 您的检索式:作者名="Dafoe"
    题名 作者 年代 出处 被引量
1Endothelium-derived essential signals involved in pancreas organogenesis显示文摘Endothelial cells(ECs) are essential for pancreas differentiation, endocrine specification, and endocrine function. They are also involved in the physiopathology of type 1 and type 2 diabetes. During embryogenesis, aortic ECs provide specific factors that maintain the expression of key genes for pancreas development such as pancreatic and duodenal homeobox-1. Other unknown factors are also important for pancreatic endocrine specification and formation of insulin-producing beta cells. Endocrine precursors proliferate interspersed with ductal cells and exocrine precursors and, at some point of development, these endocrine precursors migrate to pancreatic mesenchyme and start forming the islets of Langerhans. By the end of the gestation and close to birth, these islets contain immature beta cells with the capacity to express vascular endothelial growth factor and therefore to recruit ECs from the surrounding microenvironment. ECs in turn produce factors that are essential to maintain insulin secretion in pancreatic beta cells. Once assembled, a cross talk between endocrine cells and ECs maintain the integrity of islets toward an adequate function during the whole life of the adult individual. This review will focus in the EC role in the differentiation and maturation of pancreatic beta cells during embryogenesis as well as the current knowledge about the involvement of endothelium to derive pancreatic beta cells in vitro from mouse or human pluripotent stem cells.Dodanim Talavera-Adame Donald C Dafoe 2015World Journal of Experimental Medicine2015,5,2:2
2Proteomic analysis of hybrid poplar xylem sap 显示文摘Dafoe N J Constabel C P 2009Phytochemistry2009,70,7:1
3A first principles approach to identifying polymers for use in two-phase partitioning bioreactors 显示文摘Parent JS Capela M Dafoe JT 2012Journal of Chemical Technology and Biotechnology2012,87,8:1
4Double adult renal allografts a technique for expansion of the cadaveric kidney donor pool 显示文摘Johnson LB Kno PC dafoe DC 1996Surgery1996,120,:1
5Higher-order tooth flank form error correction for face-milled spiral bevel and hy- poid gears显示文摘FAN Qi Dafoe R Swanger J W 2008ASME Journal of Mechanical Design2008,130,07:1
6Higher-order tooth flank form error correction for face-milled spiral bevel and hypoid gears显示文摘Q Fan R S DaFoe J W Swanger 2008ASME Journal of Mechanical Design2008,130,7:1
7The physical welfare of the dionne quintuplets 显示文摘Dafoe AR Dafoe WA 1937Canadian Medical Association Journal1937,37,5:1
8Benificial effects of fetal liver tissue on fetal pancreatic transplantation 显示文摘Tafra L Berezniak R Dafoe DC 1990Surgery1990,108,4:1
9Surgical mask vs N95 respirator for preventing influenza among health care workers: a randomized trial显示文摘Loeb M Dafoe N Mahony J 2009JAMA2009,302,17:1
10The dionne quintuplets显示文摘Dafoe AR 1934Jama1934,103,9:1
11Percutaneous transluminal angioplasty treatment of renal transplant artery stenosis 显示文摘 Dafoe DC Shoenfeld RB 1982Transplantation1982,34,6:1
12Management of the post- myocardial infarction patient: a consensus report-revision of 1991 CCS guidelines显示文摘Fallen EL Cairns J Dafoe W 1995Can J Cardiol1995,11,:1
13Higher-order tooth flank form error correction for face-milled spiral bevel and hypoid gears显示文摘FAN Q DAFOE R S SWANGER J W 2008Journal of Mechanical Design2008,130,07:1
14Higher-order tooth flank form error correction for face-milled spiral bevel and hypoid gears 显示文摘Fan Q DaFoe R S Swanger J W 2008Journal of Mechanical Design2008,130,07:1
15Corrosive esophagitis显示文摘Dafoe CS 1969Thorax1969,24,:1
16Necrotizing fasciitis 显示文摘Green RJ Dafoe DC Raffin TA 1996Chest1996,110,1:1
17Higher-order Tooth Flank Form Error Correction for Face-milled Spiral Bevel and Hypoid Gears显示文摘Fan Q DaFoe R S Swanger J W 2008ASME Journal of Mechanical Design2008,130,07:1
18Higher-order tooth flank form error correction for face-milled spiral bevel and hypoid gears 显示文摘Fan Qi DaFoe R S Swanger J W 2008ASME Journal of Mechanical Design2008,130,7:1
19Patterns of volunteerism,testing,and exclusion among potential living kidney donors显示文摘Kayler LK Armenti VT Dafoe DC 0,,04:1
20POSTTRANSPLANT LYMPHOPROLIFERATTVE DISORDERS AND EPSTEIN-BARR VIRUS PROPHYLAXIS显示文摘Paul C. Kuo Donald C. Dafoe Edward J. Alfrey Richard K. Sibley John D. Scandling 1995Transplantation1995,,1:1
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