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| 1 | Type 2 diabetes mellitus and CA 19-9 levels显示文摘AIM:To prospectively investigate serum CA 19-9 levels in type 2 diabetic patients in comparison with age-and gender-matched control subjects. METHODS:We recorded duration of diabetes and examined fasting glucose levels,HbA1c levels and serum CA 19-9 levels in 76 type 2 diabetic patients and 76 controls.Abdominal CT was performed in order to eliminate abdominal malignancy in the diabetic and control groups. RESULTS:The average CA 19-9 level was 46.0±22.4 U/mL for diabetic patients whereas it was 9.97±7.1 U/mL for the control group(P<0.001).Regression analysis showed a positive correlation between diabetes and CA 19-9 independent from age,gender,glucose level and HbA1c level(t=8.8,P<001).Two of the diabetic patients were excluded from the study because of abdominal malignancy shown by CT at the initial evaluation.For all patients,abdominal CT showed no pancreatic abnormalities. CONCLUSION:CA 19-9 is a tumor-associated antigen, which is elevated in pancreatic,upper gastrointestinal tract,ovarian hepatocellular,and colorectal cancers,as well as in inflammatory conditions of the hepatobiliary system,biliary obstruction and in thyroid diseases. Diabetes has been claimed to be a risk factor for pancreatic cancer,which is increasing its incidence and has one of the lowest survival rates of all cancers.CA 19-9 is used in the diagnosis of pancreatic cancer but is also a marker of pancreatic tissue damage that might be caused by diabetes.We propose that a higher cut- off value of CA 19-9 should be used in diabetics to differentiate benign and malignant pancreatic disease, and subtle elevations of CA 19-9 in diabetics should be considered as the indication of exocrine pancreatic dysfunction. | Oya Uygur-Bayramicli Resat Dabak Ekrem Orbay Can Dolapclo■lu Mehmet Sargin Gamze Kilico■lu Yüksel Güleryüzlü Alpaslan Mayada■li | 2007 | World Journal of Gastroenterology2007，13，40： | 63 |
| 2 | A clinical dilemma:abdominal tuberculosis显示文摘AIM: To evaluate the clinical, radiological and microbiological properties of abdominal tuberculosis (TB) and to discuss methods needed to get the diagnosis.METHODS: Thirty-one patients diagnosed as abdominal TB between March 1998 and December 2001 at the Gastroenterology Department of Kartal State Hospital,Istanbul, Turkey were evaluated prospectively. Complete physical examination, medical and family history, blood count erythrocyte sedimentation rate, routine biochemical tests,Mantoux skin test, chest X-ray and abdominal ultrasonography (USG) were performed in all cases, whereas microbiological examination of ascites, upper gastrointestinal endoscopy, colonoscopy or barium enema, abdominal tomography, mediastinoscopy, laparoscopy or laparotomy were done when needed.RESULTS: The median age of patients (14 females, 17males) was 34.2 years (range 15-65 years). The most frequent symptoms were abdominal pain and weight loss.Eleven patients had active pulmonary TB. The most common abdominal USG findings were ascites and hepatomegaly. Ascitic fluid analysis performed in 13 patients was found to be exudative and acid resistant bacilli were present in smear and cultured only in one patient with BacTec (3.2 %). Upper gastrointestinal endoscopy yielded nonspecific findings in 16 patients. Colonoscopy performed in 20 patients showed ulcers in 9 (45 %), nodules in 2 (10 %)and, stricture, polypoid lesions, granulomatous findings in terminal ileum and rectal fistula each in one patient (5 %).Laparoscopy on 4 patients showed dilated bowel loops,thickening in the mesentery, multiple ulcers and tubercles on the peritoneum. Patients with abdominal TB were divided into three groups according to the type of involvement.Fifteen patients (48 %) had intestinal TB, L1 patients (35.2 %) had tuberculous peritonitis and 5 (16.8 %)tuberculous lymphadenitis. The diagnosis of abdominal TB was confirmed microbiologically in 5 (16 %) and histopathologically in 19 patients (60.8 %). The remaining nine patients (28.8 %) had been diagnosed by a positive response to antituberculous treatment.CONCLUSION: Neither clinical signs, laboratory, radiological and endoscopic methods nor bacteriological and histopathological findings provide a gold standard by themselves in the diagnosis of abdominal TB. However, an algorithm of these diagnostic methods leads to considerably higher precision in the diagnosis of this insidious disease which primarily necessitate a clinical awareness of this serious health problem. | Oya Uygur-Bayramili Gül Dabak Resat Dabak | 2003 | World Journal of Gastroenterology2003，9，5： | 20 |
| 3 | Severe thiamine deficiency in sheep with acute ruminal lactic acidosis 显示文摘 | KARAPINAR T DABAK M KIZIL O | 2008 | Journal of Veterinary Internal Medicine2008，22，3： | 1 |
| 4 | Risk of endocrine pancreatic insufficiency in patients receiving adjuvant chemoradiation for resected gastric cancer显示文摘 | Cengiz Gemici Mehmet Sargin Oya Uygur-Bayramicli Alpaslan Mayadagli Gokhan Yaprak Resat Dabak Mihriban Kocak | 2013 | Radiotherapy and Oncology2013，，2： | 1 |
| 5 | Subungual glomus tumours of the hand:diagnosis and treatment of 14 cases显示文摘 | Tomak Y Akcay I Dabak N | 2003 | Scand J Plast Reconstr Surg Hand Surg2003，，： | 1 |
| 6 | Design of a muhiband OFDM system for realistic UWB channel environments 显示文摘 | BATRA A BALAKRISHNAN J AIELLO G R FOERSTER J R DABAK A | 2004 | IEEE Transactions on Microwave Theory and Techniques2004，52，9： | 1 |
| 7 | Effects of silymarin on methotrexate-induced nephrotoxicity in rats显示文摘 | Dabak DO Kocaman N | 2015 | Ren Fail2015，37，4： | 1 |
| 8 | Thiamine deficiency in sheep with chronic rumen acidosis 显示文摘 | DABAK M GUL Y | 2004 | The Veterinary Re- cord2004，154，2： | 1 |
| 9 | Type 2 diabetes mellitus and CAl99 levels显示文摘 | Uyg1lr-Bayramicli O Dabak R Orbay E et a1 | 2013 | World J Gaatroenter2013，13，20： | 1 |
| 10 | Synthesis and investigation of tuberculosis inhibition activities of some 1,2,3-triazole derivatives显示文摘 | Dabak K Sezer O Akar A | 2003 | European Journal of Medicinal Chemistry2003，38，2： | 1 |
| 11 | Determination of ghrelin immunoreactivity in kidney tissues of diabetic rats显示文摘 | Kuloglu T Dabak DO | | 0，，7： | 1 |
| 12 | Synthesis and investiga tion of tuberculosis inhibition activities of some 1,2,3-triazole derivatives显示文摘 | Dabak K Sezer O Akar A | 2003 | European Journal of Medicinal Chemistry2003，38，2： | 1 |
| 13 | Type 2 diabetes mellitus and CA199 levels 显示文摘 | Uygur - Bayramieli O Dabak R Orbay E | 2007 | World J Gastroenterol2007，13，40： | 1 |
| 14 | Effect of joint motion on safety of portals in posterior ankle arthroscopy 显示文摘 | URGUDEN M CEVIKOL C DABAK T K | 2009 | Arthroscopy2009，25，12： | 1 |
| 15 | Evaluation of primary bone lymphoma and the importance of positron emission tomography显示文摘 | Cirakli A Elli M Dabak N | 2014 | Acta Orthop Traumatol Turc2014，48，： | 1 |
| 16 | Outcome of surgical treatment for patellar fractures 显示文摘 | Ozdemir H Ozenci H Dabak K | 2001 | Ulus Trauma Derg2001，7，1： | 1 |
| 17 | Synthesis and in- vestigation of tuberculosis inhibition activities of some 1,2,3-triazole derivatives显示文摘 | Dabak K Sezer 0 Akar A | 2003 | Eur J Med Chem2003，38，2： | 1 |
| 18 | Distribution and evaluation of bone and soft tissue tumors in the middle Black Sea Region显示文摘 | Dabak N Clrakll A Gtilman B | 2014 | Acta Orthop Traumatol Turc2014，48，1： | 1 |
| 19 | A multi-band OFDM system for UWB communication显示文摘 | BALAKRISHNAN J BATRA A DABAK A | 2003 | IEEE Conference on Ultra Wide- band Systems and Technologies2003，21，2： | 1 |
| 20 | A clinical dilemma:abdominal tuberculosis显示文摘 | Uygur-Bayramic OL Dabak C Dabak R | 2003 | World J Gyastroenterol2003，9，5： | 1 |
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