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27篇 您的检索式:作者名="DYLAN M"
    题名 作者 年代 出处 被引量
1NOD2 and ATG16L1 polymorphisms affect monocyte responses in Crohn's disease显示文摘AIM:To assess whether polymorphisms in NOD2 and ATG16L1 affect cytokine responses and mycobacterium avium subspecies paratuberculosis (MAP) survival in monocytes from Crohn's disease (CD) patients.METHODS:Monocytes were isolated from peripheral blood of CD patients of known genotype for common single nucleotide polymorphisms of NOD2 and ATG16L1.Monocytes were challenged with MAP and bacterial persistence assessed at subsequent time-points.Cytokine responses were assayed using a Milliplex multi-analyte profiling assay for 13 cytokines.RESULTS:Monocytes heterozygous for a NOD2 polymorphism (R702W,P268S,or 1007fs) were more permissive for growth of MAP (P=0.045) than those without.There was no effect of NOD2 genotype on subsequent cytokine expression.The T300A polymorphism ofATG16L1 did not affect growth of MAP in our model (P=0.175),but did increase expression of cytokines interleukin (IL)-10 (P=0.047) and IL-6 (P=0.019).CONCLUSION:CD-associated polymorphisms affected the elimination of MAP fromex vivo monocytes (NOD2),or expression of certain cytokines (ATG16L1),implying independent but contributory roles in the pathogenesis of CD.Dylan M Glubb Richard B Gearry Murray L Barclay Rebecca L Roberts John Pearson Jacqui I Keenan Judy McKenzie Robert W Bentley 2011World Journal of Gastroenterology2011,17,23:2
2Characteristic Impedance De-termination Using Propagation Constant Measurement显示文摘Roger B M Dylan F W 1991IEEE Microwave and Guided Wave Letters1991,,1:1
3Providing social support may be more beneficial than receiving it: Results from a prospective study of mortality显示文摘Stephanie L B Randolph M N Amiram D V Dylan M S 2003Psychology Science2003,,4:1
4Kinetics and thermodynamics of atmospherically relevant aqueous phase reactions ofa-pinene oxide显示文摘Dylan B Bleier EIord M J 2013J Phys ChemA2013,117,20:1
5Image processing with the radial Hilbert transform:theory and experiments显示文摘Jeffrey A Davis Dylan E McNamara Don M Cottrell 2000Optics Letters2000,25,2:1
6Meta-analysis:angiotensin-receptor blockers in chronic heart failure and high-risk acute myocardial infarction显示文摘Lee VC Rhew DC Dylan M 2004Ann Intern Med2004,141,9:1
7Meta-analysis: angiotensinreceptor blockers in chronic heart failure and high-risk acute myocardial infarction显示文摘Lee V C Rhew D C Dylan M 2004Ann Intern Med2004,141,9:1
8Metalloproteinase Inhibitors:Biological Actions and Therapeutic Opportunities显示文摘Andrew H B Dylan R E Gillian M 2002Journal of Cell Science2002,115,19:1
9Burns caused by steam inhalation for respiratory in children显示文摘Siun MM Dylan M Susan S 0,,10:1
10A light hydrocarbon fuel processor producing high-purity hydrogen显示文摘Dainiel G L Kyle T Dylan M 2003J Power Sources2003,117,12:1
11Hospitals' compliance with prophylaxis guidelines for venous thromboembolism显示文摘Yu H T Dylan M L LinJ 2007Am J Health Syst Pharm2007,64,1:1
12Mortali-ty differences among organisms causing septicemiain hemodialysis patients显示文摘Danese M D Griffiths R I Dylan M 2006Hemodial Int2006,10,:1
13Mortality differences among organisms causing septicemia in hemodialysis patients显示文摘Danese MD Griffiths RI Dylan M 2006Hemodial Int2006,10,1:1
14Meta analysis: angiotensin receptor blockers in chronic heart failure and high risk acute myocardial infarction 显示文摘VICTOR LEE C DAVID RHEW C DYLAN M 2004Ann Int Med2004,141,9:1
15PTH and the risks for hip, vertebral, and pelvic fractures among patients on dialysis显示文摘Danese M D Kim] Doan Q V Dylan M Griffiths R Chertow G M 2006AmJ Kidney Dis2006,47,:1
16Progress in coupling models of human and coastal landscape change 显示文摘MURRAY A B SATHYA G DYLAN E M 2013Computers & geoscienees2013,53,:1
17Burns caused by steam inhalation for respiratory tract infections in children 显示文摘Siun MM Dylan M Susan S 2004BMJ2004,328,10:1
18Bums caused by steam inhalation for respiratory tract infections in children 显示文摘SIUN M M DYLAN M SUSAN S 2004BMJ2004,328,10:1
19Specific requirements of MRFs for the expression of muscle specific microRNAs, miR-1, miR-206 and miR-133显示文摘Dylan Sweetman Katarzyna Goljanek Tina Rathjen Svetlana Oustanina Thomas Braun Tamas Dalmay Andrea Münsterberg 2008Developmental Biology2008,,2:1
20Meta-analysis: Angiotensin-receptor blockers in chronic heart failure and high-risk acute myocardial infarctiml显示文摘Lee V C Rhew D C Dylan M 2004Ann Intern Med2004,141,9:1
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