|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Skin rejuvenation using intense pulsed light-a randomized controlled splitface trial with blinded response evaluation显示文摘 | Hedelund L Due E Bjerring P | 2006 | Arch Dermatol2006，142，： | 1 |
| 2 | B-type natriuretie peptide and renal function in the diagnosis of heart failure : ananalysis from the Breathing Not Properly Multinational Study 显示文摘 | MeCullough PA Due P Omland T | 2003 | Am J Kidney Dis2003，41，3： | 1 |
| 3 | Conservative therapy in patients with anterior disc displacement without reduction using 2 common splints: a randomized clinical trial 显示文摘 | Schmitter M Zahran M Due JM Henschel V Rammelsberg P | 2005 | J Oral Maxillofac Surg2005，63，9： | 1 |
| 4 | The persistent release of HMGBI contributes to tactile hyperalgesia in a rodent model of neuropathic pain显示文摘 | Feldman P Due MR Ripsch MS | 2012 | J Neuroinflammation2012，9，： | 1 |
| 5 | Skin rejuvenation using intense pulsed light:a randomized controlled split-face trial with blinded response evaluation显示文摘 | HEDELUND L DUE E BJERRING P | 2006 | Arch Dermatol2006，142，8： | 1 |
| 6 | Crystallization of cellulose-/V-methylmorpholine-TV-oxide hydrate solutions 显示文摘 | BIGANSKA O NAVARD P BE DUE O | 2002 | Polymer2002，43，23： | 1 |
| 7 | Effectiveness of continuous veno-venous hemofiltration and intermittent hemodialysis in the treatment of severe acute phenobarbital poisoning显示文摘 | Thuan LQ Ngoc ND Due P | 2013 | APJMT2013，，： | 1 |
| 8 | Personal, social and environmental factors regarding fruit and vegetable intake among schoolchildren in nine European countries 显示文摘 | SANDVIK C DE BOURDEAUDHUIJ I DUE P | 2005 | Ann Nutr Metab2005，49，4： | 1 |
| 9 | Reliability and validity of a questionnaire to measure personal,social and environmental correlates of fruit and vegetable intake in 10-11-year-old children in five European countries 显示文摘 | De BOURDEAUDHUIJ I KLEEP KI DUE P | 2005 | Publ Health Nutr2005，8，2： | 1 |
| 10 | Social relations: network-support and relational strain显示文摘 | Due P Holstein B Lund R | 1999 | Soc Sci Med1999，48，5： | 1 |
| 11 | B-type natfiuretic peptide and renal function in the diagnosis of heart failure: an analysis from the Breathing Not Properly Muhinational Study显示文摘 | McCullough PA Due P Omland T | 2003 | Am J Kidney Dis2003，41，3： | 1 |
| 12 | The persistent release of HMGB1 contributes to tactile hyperalgesia in a rodent model of neuropathic pain显示文摘 | Feldman P Due MR Ripsch MS | 2012 | J Neuroinflam2012，9，： | 1 |
| 13 | An exposure chamber for studies on human perception of DC electrie fields and ions显示文摘 | Due Hai Nguyen Sarma Maruvada P | 1994 | IEEE Transactions on Power Delivery1994，9，4： | 1 |
| 14 | HCV-specific immune responses induced by CIGB-230 in combination with IFN-α plus ribavirin显示文摘AIM:To analyze hepatitis C virus(HCV)-specific immune responses in chronically infected patients under triple therapy with interferon-α(IFN-α)plus ribavirin and CIGB-230.METHODS:CIGB-230 was administered in different schedules with respect to IFN-αplus ribavirin therapy.Paired serum and peripheral blood mononuclear cells(PBMC)samples from baseline and end of treatment were analyzed.The HCV-specific humoral response was tested by enzyme-linked immunosorbent assay,neutralizing antibodies were evaluated by cell culture HCV neutralization assays,PBMC proliferation was assayed by carboxyfluorescein succinimidyl ester staining and IFN-γsecretion was assessed by enzyme-linked immunospot.Data on virological and histological response and their association with immune variables are also provided.RESULTS:From week 12 to week 48,all groups of patients showed a significant reduction in mean leukocyte counts.Statistically significant reductions in antibody titers were frequent,but only individuals immunized with CIGB-230 as early add-on treatment sustained the core-IgG response,and the neutralizing antibody response was enhanced only in patients receiving CIGB-230.Cell-mediated immune responses also tended to decline,but significant reductions in IFN-γsecretion and total absence of core-specific lymphoproliferation were exclusive of the control group.Only CIGB-230-immunized individuals showed de novo induced lymphoproliferative responses against the structural antigens.Importantly,it was demonstrated that thequality of the CIGB-230-induced immune response depended on the number of doses and timing of administration in relation to the antiviral therapy.Specifically,the administration of 6 doses of CIGB-230 as late addon to therapy increased the neutralizing antibody activity and the de novo core-specific IFN-γsecretion,both of which were associated with the sustained virological response.CONCLUSION:CIGB-230,combined with IFN-α-based therapy,modifies the immune response in chronic patients.The study provides evidence for the design of more effective therapeutic vaccine interventions against HCV. | Yalena Amador-Caizares Gillian Martínez-Donato Liz lvarez-Lajonchere Claudia Vasallo Mariacarla Dausá Daylen Aguilar-Noriega Carmen Valenzuela Ivette Raíces Jean Dubuisson Czeslaw Wychowski Zurina Cinza-Estévez Marlén Castellanos Magdalys Núez Anny Armas Yaimé González Ismariley Revé Ivis Guerra ngel Pérez Aguiar Santiago Dueas-Carrera | 2014 | World Journal of Gastroenterology2014，20，1： | 1 |
| 15 | Cohabitation and marital status as pre- dictors of mortality: an eight year follow - up study 显示文摘 | LUND R DUE P MODVIG J HOLSETIN BE DAMSGAARD MT ANDERSEN PK | 2002 | Social Science & Medicine2002，55，： | 1 |
| 16 | Effectiveness of continuous veno-venous hemofiltration and intermittent hemodialysis in the treatment of severe acute phenobarbital poisoning显示文摘 | Thuan LQ Ngoc ND Due P | 2013 | APJMT2013，3，1： | 1 |
| 17 | Machine learning in preoperative glioma MRl:Survival associations by perfusion - based support vector machine outperforms traditional MRI 显示文摘 | Emblem KE Due Tonnessen P Hald JK | 2014 | J Magn Reson Imaging2014，40，1： | 1 |
| 18 | Force magnet saturation显示文摘 | Grauers A Kasinathan P and Hamdi E density limits machine due in low-speed permanent S | 2005 | IEEE Transaction on Energy Conversion2005，20，1： | 1 |
| 19 | B-type natriuretic peptide and renal function in the diagnosis of heart failure:an analysis from the Breathing Not Properly Multinational Study显示文摘 | McCullough PA Due P Omland T | 2003 | Am J Kidney Dis2003，41，： | 1 |
| 20 | Effects of Atorvastatin on Vitamin D Levels in Patients With Acute Ischemic Heart Disease显示文摘 | José L. Pérez-Castrillón Gemma Vega Laura Abad Alberto Sanz José Chaves Gonzalo Hernandez Antonio Due?as | 2007 | The American Journal of Cardiology2007，，7： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员