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| 1 | Role of MMP-2 and MMP-9 and their natural inhibitors in liver fibrosis, chronic pancreatitis and non-specific inflammatory bowel diseases显示文摘BACKGROUND: There is a growing evidence that matrix metalloproteinase (MMP)-2 and MMP-9 (gelatinases) play an important role in the pathogenesis of numerous disorders especially with inflammatory etiology and extracellular matrix (ECM) remodeling. Despite the fact that gelatinases involve in liver cirrhosis is provided in the literature, their role in the pathogenesis of chronic pancreatitis and non-specific inflammatory bowel diseases is still under investigation.DATA SOURCES: We carried out a PubM ed search of English language articles relevant to the involvement of gelatinases in the pathogenesis of liver fibrosis, pancreatitis, and non-specific inflammatory bowel diseases.RESULTS: The decreased activity of gelatinases, especially MMP-2, is related to the development of liver fibrosis, probably due to the decrease of capability for ECM remodeling. Similar situation can be found in chronic pancreatitis; however reports on this matter are rare. The presence of non-specific inflammatory bowel diseases results in MMP-9 activity elevation.CONCLUSION: The fluctuation of gelatinases activity during liver fibrosis, chronic pancreatitis and non-specific inflammatorybowel diseases is observed, but the exact role of these enzymes demands further studies. | Jacek Kurzepa Agnieszka M?dro Gra?yna Czechowska Joanna Kurzepa Krzysztof Celiński Weronika Kazmierak Maria S?omka | 2014 | Hepatobiliary & Pancreatic Diseases International2014，13，6： | 15 |
| 2 | Removal of NOx by DC and pulsed corona discharges in a wet electrostatic precipitator model 显示文摘 | Dros M Round G F | 1998 | Journal of Electrostatics1998，45，4： | 2 |
| 3 | Characterization of the integration and modular excision of the integrative conjugative element PAISt in Streptomyces turgidiscabies Car8显示文摘 | Huguet-Tapia JC Bignell DRO Loria R | 2014 | PLoS One2014，9，99： | 1 |
| 4 | Identification of polymorphs of pentacene显示文摘 | Christine C Mattheus Anne B Dros Jacob Baas | 2003 | Synthetic metals2003，138，： | 1 |
| 5 | Effect of Pb ions on superoxide dismutase and catalase activities in leaves of pea plants grown in high and low irradiance显示文摘 | E. Romanowska B. Wróblewska A. Dro?ak M. Zienkiewicz M. Siedlecka | 2008 | Biologia Plantarum2008，，1： | 1 |
| 6 | Removal of NOx by DC and pulsed corona discharges in a wet electrostatic precipitator model显示文摘 | Mizeraczyk J Czech T 1998 | 1998 | Journal of Electrostatics1998，45，： | 1 |
| 7 | Dependence of PCDD and PCDF levels in human milk on various parameters in Germany Ⅱ 显示文摘 | Beck H Droβ A Mathar W | 1992 | Chemosphere1992，25，710： | 1 |
| 8 | Removal of NOx by DC and pulsed corona discharges in a wet electrostatic precipitator model 显示文摘 | Dros M Round G F | 1998 | Journal of Electrostatics1998，45，4： | 1 |
| 9 | Technology and potential of wear resistant thermal spray coatings 显示文摘 | Bach Fr W Mohwald K Droβler B | 2005 | Ma terialwissenschaft und Werkstofftechnik2005，36，8： | 1 |
| 10 | Vegetative growth, stomatal resistance,photosyntteetic efficiency and yield of watermel- on plants under different water levels显示文摘 | De Melo Alberto Soares Janivan Fernandes Suassuna Pe- dro Dantas Fernandes | 2010 | Aeta Scientiarum- Agronomy2010，32，1： | 1 |
| 11 | Sidiam giycodcoxycholate and spinabiluty of gastroitestinalmucas:protective effect of smeceite显示文摘 | DRO M T | | 0，，07： | 1 |
| 12 | Non-isothermal Studies on Mechanism And Kinetics of Thermal Decomposition of Cobalt(II) Oxalate Dihydrate显示文摘 | B. Ma?ecka E. Dro?d?-Cie?la A. Ma?ecki | 2002 | Journal of Thermal Analysis and Calorimetry2002，，3： | 1 |
| 13 | Identification of polymorphs of pentacene显示文摘 | MATTHEUS C H DROS A B BAAS J | 2003 | Synthetic Metals2003，138，： | 1 |
| 14 | Analysis of PI3K/AKT/mTOR signalling pathway in high risk neuroblastic tumours显示文摘 | I?ycka–?wieszewskaE Dro?yńskaE RzepkoR | 2010 | Pol J Pathol2010，61，19： | 1 |
| 15 | Anthocyanin analysis by HPLC/MS 显示文摘 | Heier A Blaas W Dro 13 A | 2002 | Am J Enol Vitic2002，53，： | 1 |
| 16 | Method of de-noising by spectral subtraction applied to the detection of rolling bearing defects显示文摘 | Estocq P Bolaers F Dro J P | 2006 | Journal of Vibration and Control2006，12，2： | 1 |
| 17 | Thoraeoscopy for autonomic: disorders显示文摘 | CLAES G DRO]-I' C GOTHBERG G | 1993 | Am Thorae Surg1993，56，： | 1 |
| 18 | Catechol-O-methyltransferase and monoamine oxidase B genes andsusceptibility to sporadic Parkinson,s disease in a Polish population显示文摘 | Bialecka M Dro^dzik M Honczarenko K | 2005 | Eur Neurol2005，53，： | 1 |
| 19 | An ex-post analysis of the effect of re- newables and cogeneration on Spanish electricity prices 显示文摘 | LILIANA GELABERT XAVIER LABANDEIRA PE- DRO LINARES | 2011 | Energy economics2011，33，12： | 1 |
| 20 | Dizziness reported by elderly patients in family practice:prevalence,incidence,and clinical characteristics显示文摘 | Maarsingh OR Dros J Schellevis FG | 2010 | BMC Fam Pract2010，11，： | 1 |
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