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1Trend of declining stroke mortality in China:reasons and analysis显示文摘Introduction There is a downward trend of stroke-related mortality in the USA.By reviewing all published articles on stroke mortality in China,we analysed its trend and possible factors that have influenced the trend.Methods Both English and Chinese literatures were searched on the mortality of stroke or cerebrovascular diseases in China.Potential papers related to this topic were identified from PubMed,Medline,Embase,Cochrane Library,Wanfang Database,SINOMED and China National Knowledge Infrastructure databases.Results Comparing the results from the most recent population-based epidemiological survey and databank from the national Center for Disease Control and Prevention,the age-adjusted stroke mortality rate has shown a downward trend among both urban and rural population in the past 30 years in China.Comparing with 30 years ago,the rate of stroke mortality has decreased by more than 31%in urban/suburban population and 11%in rural population.In men,the age-adjusted stroke mortality rate decreased by 18.9%and in women by 24.9%between 1994 and 2013.Factors that may have contributed to the trend of decreased stroke mortality rate include(1)improved healthcare coverage and healthcare environment;(2)improved treatment options and medical technology;(3)support by government to educate the public on stroke and stroke prevention;and(4)improved public knowledge on stroke.Conclusions The age-adjusted stroke mortality rate in China has shown a downward trend among both urban and rural population in the past 30 years.The major influencing factors that helped in reducing stroke mortality in China included improved healthcare coverage,healthcare environment,the updated treatment options and modern medical technology.Wenzhi Wang David Wang Hongmei Liu Haixin Sun Bin Jiang Xiaojuan Ru Dongling Sun Zhenghong Chen Yongjun Wang 2017Stroke & Vascular Neurology2017,2,3:52
2MEKK1, MKK1/MKK2 and MPK4 function together in a mitogen-activated protein kinase cascade to regulate innate immunity in plants显示文摘激活 Mitogen 的蛋白质 kinase (MAPK ) 串联在调整植物起重要作用天生的有免疫力的回答。在到为有组成的防卫回答的异种的搜索的一幅基因屏幕,我们识别了展出房间死亡和组成的防卫回答的 mpk4 和 mekk1 的多重等位基因。双分子的荧光互补(BiFC ) 分析证明 MPK4 和 MEKK1 与 MKK1 和 MKK2 交往,二密切相关的 MAPK kinases。mkk1 和 mkk2 单身者异种植物没有明显的变异的显型。测试 MKK1 和 MKK2 是否冗余地工作, mkk1 mkk2 两倍异种被产生。mkk1 mkk2 两倍变异的植物在幼苗舞台和幼苗致命性显型死是温度依赖者。类似于 mpk4 和 mekk1 异种,两倍变异的幼苗积累的 mkk1 mkk2 H2O2 高级,显示自发的房间死亡,联系的组成地快速的致病(PR ) 基因和展览病原体抵抗。另外,由 flg22 的 MPK4 的激活在 mkk1 mkk2 被损害两倍异种,在地图 kinase 串联和 MPK4 和 MEKK1 建议那 MKK1 和 MKK2 功能否定地在植物调整天生的有免疫力的回答。Minghui Gao Jinman Liu Dongling Bi Zhibin Zhang Fang Cheng2, Sanfeng Chen Yuelin Zhang 2008Cell Research2008,18,12:37
3Knockdown of CD146 reduces the migration and proliferation of human endothelial cells显示文摘我们的以前的学习证明了那个 CD146 分子是脉管的内皮细胞层上的一个简历标记,它涉及 angiogenesis 和肿瘤生长。然而机制在后面不是清楚的。这里,我们第一次用 CD146 siRNA 开发了一个新奇 CD146 封锁系统在 endothelial 房间上学习它的功能。我们的数据证明 CD146 siRNA 明确地在 mRNA 和蛋白质层次上堵住了 CD146 的表达式,导致 HUVEC 增长,粘附和移植的重要抑制。这些结果证明 CD146 在脉管的 endothelial 房间活动和 angiogenesis 起一个关键作用,并且 CD146 siRNA 能为 anti-angiogenesis 治疗被用作一个新禁止者。Yanyong Kang Fengcai Wang Jing Feng Dongling Yang Xu Yang Xiyun Yan 2006Cell Research2006,16,3:33
4Genetic diversity of rice cultivars (Oryza sativa L.) in China and the temporal trends in recent fifty years显示文摘To understand geographical distribution of the genetic diversity of rice cultivars {Oryza sativa L.) and its trends in recent fifty years in China, 453 ’ accessions were analyzed by 36 microsatellites loci and 42 phenotypic traits. Results revealed that the genetic diversity by SSRs is highly consistent with that by phenotypic traits and the genetic diversity of indica cultivars was higher than that of japonica cultivars; the genetic diversity of cultivars declined from 1950s to 1980s and then increased greatly; among the six rice ecological zones (REZs), genetic diversity of REZTl was the highest and those of REZV and REZVT were the lowest at both DNA and phenotypic level. Jiangsu and Jiangxi provinces in the middle and lower reaches of Yangtze River and Sichuan province in southwest of China were the areas with the highest genetic diversity. Breeders in REZV which is an important japonica rice area but with very low genetic diversity should explore more gene resources to widen the genetic backgrounds of cultivars.QI Yonawen ZHANG Dongling ZHANG Hongliang WANG Meixing SUN Junli WEI Xinghua QIU Zongen TANG Shengxiang CAO Yongsheng WANG Xiangkun LI Zichao 2006Chinese Science Bulletin2006,51,6:27
5Macrophagic CD146 promotes foam cell formation and retention during atherosclerosis显示文摘Yongting Luo Hongxia Duan Yining Qian Liqun Feng Zhenzhen Wu Fei Wang Jing Feng Dongling Yang Zhihai Qin Xiyun Yan 2017Cell Research2017,27,3:18
6Similarity criteria and coal-like material in coal and gas outburst physical simulation显示文摘Bo Zhao Guangcai Wen Haitao Sun Dongling Sun Huiming Yang Jie Cao Linchao Dai Bo Wang 2018International Journal of Coal Science & Technology2018,5,2:17
7Chinese Stroke Association guidelines for clinical management of cerebrovascular disorders:executive summary and 2019 update of the management of high-risk population显示文摘Aim Cerebrovascular disease is the leading cause of death and disability in China,causing a huge burden among patients and their families.Hence,stroke prevention is critical,especially in the high-risk population.Here,we present the evidence-based guideline suitable for the Chinese population.Methods Literature search of PubMed and Cochrane library(from January 1964 to June 2019)was done.After thorough discussion among the writing group members,recommendations were listed and summarised.This guideline was reviewed and discussed by the fellow writing committees of the Chinese Stroke Association’s Stroke.Results This evidence-based guideline was written in three parts:controlling the risk factors of stroke,utilisation of antiplatelet agents and assessing the risks of first-ever stroke.All recommendations were listed along with the recommending classes and levels of evidence.Conclusions This guideline provides recommendations for primary prevention of cerebrovascular disease among high-risk population in China.Controlling related risk factors,appropriately using antiplatelet agents,assessing the risk of developing first-ever stroke should help reduce the rate of cerebrovascular disease in China.Yilong Wang Shangrong Han Haiqiang Qin Huaguang Zheng Bin Jiang Yong Cao Yuan Gao Ling Guan Qian Jia Yong Jiang Yuming Jiao Shuya Li Yapeng Li Zixiao Li Wei Liu Xiaojuan Ru Dongling Sun Haixin Sun Penglian Wang Tingting Wang Lixia Zong Lei Guo Xuewei Xie Yuming Xu Yuyuan Xu Xiaomeng Yang Yingying Yang Mengyuan Zhou Wenzhi Wang Chinese Stroke Association Stroke Council Guideline Writing Committee 2020Stroke & Vascular Neurology2020,5,3:11
8Late Cenozoic high-resolution magnetostratigraphy in the Kunlun Pass Basin and its implications for the uplift of the northern Tibetan Plateau显示文摘The Kunlun Pass Basin, located in the middle of the eastern Kunlun Mountains, received relatively continuous late Cenozoic sediments from the surrounding mountains, archiving great information to understand the deformation and uplift histories of the northern Tibetan Plateau. The Kunlun-Yellow River Movement, identified from the tectonomorphologic and sedimentary evolution of the Kunlun Pass Basin by Cui Zhijiu et al. (1997, 1998), is roughly coincident with many important global and Plateau climatic and environmental events, becoming a crucial time interval to understand tectonic-climatic interactions. However, the ages used to constrict the events remain great uncertainty. Here, we present the results of detailed magnetostratigraphy of the late Cenozoic sediments in the Kunlun Pass Basin, which show the basin sediments were formed between about 3.6 Ma and 0.5 Ma and the Kunlun-Yellow River Movement occurred at 1.2 to ~0.78 Ma. The lithology, sedimentary facies and lithofacies associations divide the basin into five stages of tectonosedimentary evolution, indicating the northern Tibetan Plateau having experienced five episodes of tectonic uplifts at ~3.6, 2.69-2.58, 1.77, 1.2, 0.87 and ~0.78 Ma since the Pliocene.SONG Chunhui GAO Dongling FANG Xiaomin CUI Zhijiu LI Jijun YANG Shengi JIN Hongbo Douglas Burbank Joseph L. Kirschvink 2005Chinese Science Bulletin2005,50,17:10
9Identification of quantitative trait loci for the dead leaf rate and the seedling dead rate under alkaline stress in rice显示文摘The quantitative trait loci (QTLs) for the dead leaf rate (DLR) and the dead seedling rate (DSR) at the different rice growing periods after transplanting under alkaline stress were identified using an F2:3 population, which included 200 individuals and lines derived from a cross between two japonica rice cultivars Gaochan 106 and Changbai 9 with microsatellite markers. The DLR detected at 20 days to 62 days after transplanting under alkaline stress showed continuous normal or near normal distributions in F3 lines, which was the quantita- tive trait controlled by multiple genes. The DSR showed a continuous distribution with 3 or 4 peaks and was the quantitative trait con- trolled by main and multiple genes when rice was grown for 62 days after transplanting under alkaline stress. Thirteen QTLs associated with DLR were detected at 20 days to 62 days after transplanting under alkaline stress. Among these, qDLR9-2 located in RM5786?RM160 on chromosome 9 was detected at 34 days, 41 days, 48 days, 55 days, and 62 days, respectively; qDLR4 located in RM3524?RM3866 on chromosome 4 was detected at 34 days, 41 days, and 48 days, respectively; qDLR7-1 located in RM3859?RM320 on chromosome 7 was detected at 20 days and 27 days; and qDLR6-2 in RM1340-RM5957 on chromosome 6 was detected at 55 days and 62 days, respectively. The alleles of both qDLR9-2 and qDLR4 were derived from alkaline sensitive parent 'Gaochan106'. The alleles of both qDLR7-1 and qDLR6-2 were from alkaline tolerant parent Changbai 9. These gene actions showed dominance and over dominance primarily. Six QTLs associated with DSR were detected at 62 days after transplanting under alkaline stress. Among these, qDSR6-2 and qDSR8 were located in RM1340?RM5957 on chromosome 6 and in RM3752?RM404 on chromosome 8, respectively, which were asso- ciated with DSR and accounted for 20.32% and 18.86% of the observed phenotypic variation, respectively; qDSR11-2 and qDSR11-3 were located in RM536?RM479 and RM2596?RM286 on chromosome 11, respectively, which were associated with DSR explaining 25.85% and 15.41% of the observed phenotypic variation, respectively. The marker flanking distances of these QTLs were quite far ex- cept that of qDSR6-2, which should be researched further.Dongling Qi Guizhen Guo Myung-chul Lee Junguo Zhang Guilan Cao Sanyuan Zhang Seok-cheol Suh Qingyang Zhou Longzhi Han 2008Journal of Genetics and Genomics2008,35,5:8
10Late Holocene paleoenvironmental changes in the southern Okinawa Trough inferred from a diatom record显示文摘We analyzed sediment diatoms from core MD05-2908 to infer climate and paleoenvironmental changes in the southern Okinawa Trough (SOT) over the past 1000 years.Because the study area is located in the East Asia monsoon area and beneath the main axis of Kuroshio Current,the climatic and hydrographical conditions are strongly influenced by both of these factors.The species used as environmental indicators,including the Kuroshio Current species (KC species) and freshwater species,were investigated in this paper.Changes in the abundance of the two groups of species revealed significant variations in water temperature and hydrography in the SOT during the Medieval Warm Period (MWP) and the Little Ice Age (LIA).From 950-1500 AD,the abundance of the KC species increased fluctuantly,while the freshwater species decreased,showing that the influence of the Kuroshio Current was intensified at that interval and the precipitation of the study area was relatively low.The KC species decreased remarkably and was maintained at a low abundance during the interval of 1500-1900 AD,which suggests that the impact of the Kuroshio Current on the SOT weakened during the period corresponding to the LIA.Moreover,the high abundance of the freshwater species at the same interval indicates a distinct increase in precipitation in northeastern Taiwan,which may be correlated to the south-detention of the rainfall belt in China caused by the southward migration of the western Pacific subtropical high.LI DongLing JIANG Hui LI TieGang ZHAO MeiXun 2011Chinese Science Bulletin2011,56,11:8
11Geographical genetic diversity and divergence of common wild rice (O. rufipogon Griff.) in China显示文摘Using 36 SSR markers and 889 accessions of common wild rice in China, the genetic diversity and the divergence among different geographical populations are investigated. Guangdong Province has the largest number of alleles, which account for 84% of the total alleles detected in the study, followed by Guangxi Province. The Nei's gene diversity indices, from high to low, are in the sequence of Hainan, Guangdong, Guangxi, Fujian, Hunan, Jiangxi, and Yunnan provinces. Two genetic diversity centers of Chinese common wild rice are detected on the basis of geographic analysis, i.e., the region covering Boluo, Zijin, Lufeng, Haifeng, Huidong and Huiyang counties of Guangdong Province and the region covering Yongning, Longan, Laibin and Guigang counties of Guangxi Province. The common wild rice in Yunnan, Hunan, Jiangxi, and Fujian provinces are diverged into respectively independent populations with relatively large genetic distances, whereas, those in Hainan, Guangdong and Guangxi provinces have relatively low genetic divergence. Under the condition of geographic separation, natural selection is considered as one of the primary forces contributing to the divergence of common wild rice in China.WANG MeiXing ZHANG HongLiang ZHANG DongLing PAN DaJian LI DaoYuan FAN ZhiLan QI YongWen SUN JunLi YANG QingWen LI Chen LI ZiChao 2008Chinese Science Bulletin2008,53,22:8
12FXYD6: a novel therapeutic target toward hepatocellular carcinoma显示文摘FXYD6, FXYD 领域包含离子运输管理者 6,被报导了影响 Na 的活动 < 啜 class= “ a-plus-plus ” >+/K+-ATPase 并且与心理疾病被联系。这里,我们证明 FXYD6 在 hepatocellular 癌(HCC ) 是起来调整的并且提高 HCC 房间的迁居和增长。FXYD6 的起来规定不仅断然随 Na 的增加相关 < 啜 class= “ a-plus-plus ” >+/K 有它发信号的下游的 Src 英皇家空军之阶级最低之兵的激活的 +-ATPase 而且坐标小径。更重要地,显著地由它的功能的抗体堵住 FXYD6 在老鼠禁止 xenografted HCC 肿瘤的生长潜力,显示 FXYD6 代表向 HCC 的一个潜在的治疗学的目标。总的来说,我们的结果在 HCC 前进建立 FXYD6 的一个关键角色并且建议指向 FXYD6 的治疗能向 HCC 病人有益于临床的治疗。Qian Gao Xiongfei Chen Hongxia Duan Zhaoqing Wang Jing Feng Dongling Yang Lina Song Ningxin Zhou Xiyun Yan 2014Protein & Cell2014,5,7:7
13State-of-the-Art Review of High-Throughput Statistical Spatial-Mapping Characterization Technology and Its Applications显示文摘Macroscopic materials are heterogeneous,multi-elementary,and complex.No material is homogeneous or isotropic at a certain small scale.Parts of the material that differ from one another can be termed'natural chips.'At different spots on the material,the composition,structure,and properties vary slightly,and the combination of these slight differences establishes the overall material performance.This article presents a state-of-the-art review of research and applications of high-throughput statistical spatialmapping characterization technology based on the intrinsic heterogeneity within materials.Highthroughput statistical spatial-mapping uses a series of rapid characterization techniques for analysis from the macroscopic to the microscopic scale.Datasets of composition,structure,and properties at each location are obtained rapidly for practical sample sizes.Accurate positional coordinate information and references to a point-to-point correspondence are used to set up a database that contains spatialmapping lattices.Based on material research and development design requirements,dataset spatialmapping within required target intervals is selected from the database.Statistical analysis can be used to select a suitable design that better meets the targeted requirements.After repeated verification,genetic units that reflect the material properties are determined.By optimizing process parameters,the assembly of these genetic unit(s)is verified at the mesoscale,and quantitative correlations are established between the microscale,mesoscale,macroscale,practical sample,across-the-scale span composition,structure,and properties.The high-throughput statistical spatial-mapping characterization technology has been applied to numerous material systems,such as steels,superalloys,galvanization,and ferrosilicon alloys.This approach has guided the composition and the process optimization of various materials.Haizhou Wang Lei Zhao Yunhai Jia Dongling Li Lixi Yang Yuhua Lu Guang Feng Weihao Wan 2020Engineering2020,6,6:7
14Impaired tumor angiogenesis and VEGF- induced pathway in endothelial CD146 knockout mice显示文摘Qiqun Zeng Zhenzhen Wu Hongxia Duan Xuan Jiang Tao Tu Di Lu Yongting Luo Ping Wang Lina Song Jing Feng Dongling Yang Xiyun Yan 2014Protein & Cell2014,5,6:6
15Assessing indica-japonica differentiation of improved rice varieties using microsatellite markers显示文摘To assess the indica-japonica differentiation of improved rice varieties, a total of 512 modern varieties including 301 indica and 211 japonica accessions were analyzed using 36 microsatellites. The Fst coefficients ranged from 0.002 to 0.730 among the loci with an average of 0.315. Significant differentiation was detected at 94.4% of the loci studied (P<0.05, pairwise Fst tests), indicating that there was a high level of indica-japonica differentiation within the improved varieties. At 18 loci, about 74%-98% of the alleles of indica and japonica accessions were distributed in two ranges of amplicon length. Linkage disequilibrium analysis showed that the distribution trends were significantly nonrandomly associated. Using the differentiation trends at the 18 loci, microsatellite index (MI) was proposed for discrimination of the two subspecies. When rice accessions with MI value greater than zero were classified as indica, and those with MI value smaller than zero were classified as japonica, about 96.1% of the accessions could be classified. This result agrees with the classification based on morphological-physiological characters, indicating that this method is feasible and effective.Yongwen Qi Hongliang Zhang Dongling Zhang Meixing Wang Junli Sun Li Ding Fenghua Wang Zichao Li 2009Journal of Genetics and Genomics2009,36,5:5
16Genetic structure and diversity of Oryza sativa L. in Guizhou,China显示文摘Preserving many kinds of rice resources and rich variations, Guizhou Province is one of the districts with the highest genetic diversity of cultivated rice (Oryza sativa L.) in China. In the current research, genetic diversity and structure of 537 accessions of cultivated rice from Guizhou were studied using 36 microsatellite markers and 39 phenotypic characters. The results showed that the model-based genetic structure was the same as genetic-distance-based one using SSRs but somewhat different from the documented classification (mainly based on phenotype) of two subspecies. The accessions being classified into indica by phenotype but japonica by genetic structure were much more than that being classified into japonica by phenotype but indica by genetic structure. Like Ding Ying’s taxonomic sys- tem of cultivated rice, the subspecific differentiation was the most distinct differentiation within culti- vated rice. But the differentiation within indica or japonica population was different: japonica presented clearer differentiation between soil-watery ecotypes than indica, and indica presented clearer differen- tiation between seasonal ecotypes than japonica. Cultivated rices in Guizhou revealed high genetic diversity at both DNA and phenotypic levels. Possessing the highest genetic diversity and all the nec- essary conditions as a center of genetic diversity, region Southwestern of Guizhou was suggested as the center of genetic diversity of O. sativa L. from Guizhou.ZHANG DongLing ZHANG HongLiang WEI XingHua QI YongWen WANG Meixing SUN JunLi DING Li TANG ShengXiang QIU Zong'En CAO YongSheng WANG XiangKun LI ZiChao 2007Chinese Science Bulletin2007,52,3:5
17Effect of rotationally accelerated shot peening on the microstructure and mechanical behavior of a metastableβtitanium alloy显示文摘Microstructural evolution and deformation mechanism of a metastableβalloy(Ti-10 V-2 Fe-3 Al)processed by rotationally accelerated shot peening(RASP)were systematically investigated with optical microscopy,X-ray diffraction,electron backscatter diffraction and transmission electron microscopy.Different gradient hierarchical microstructures(gradients inα″martensite andβphase,and hierarchical twins range from the nanoscale to microscale)can be fabricated by RASP via changing the shot peening time.The hardening behavior and tensile mechanical properties of gradient hierarchical microstructure were systematically explored.Novel deformation twinning systems of{112}α″and{130}<310>α″in the kinkedα″martensite were revealed during the tensile deformation.It was found that stress-induced martensitic transformation,twinnedα″martensite and the related dynamic grain refinement contribute to hardness and work hardening ability.Simultaneous improvement of strength and ductility of the metastableα″titanium alloy can be achieved by introducing a gradient hierarchical microstructure.Xinkai Ma Zhuo Chen Dongling Zhong SNLuo Lei Xiao Wenjie Lu Shanglin Zhang 2021Journal of Materials Science & Technology2021,,16:4
18Fine mapping of the awn gene on chromosome 4 in rice by association and linkage analyses显示文摘Awnness is a key trait in rice domestication, yet no studies have been conducted on fine mapping or association mapping of the rice awn gene. In this study, we investigated the awnness and genotype of a core collection of 303 cultivated rice varieties and a BC5F2 segregating population of 200 individuals. Combining association and linkage analyses, we mapped the awnness related genes to chromosome 4. Primary association analysis using 24 SSR markers revealed five loci significantly associated with awnness on chromosome 4. The associated markers cover previously identified regions. Fine association mapping was conducted using another 29 markers within a 4-Mb region, covering the associated marker in34, which is close to the awn gene Awn4.1. Seven associated markers were revealed, distributed over an 870-kb region. Combining the fine association mapping and linkage analysis of awnness in the 200 BC5F2 segregating population, we finally identified a 330-kb region as the candidate region for Awn4.1. The results indicate that combining association mapping and linkage mapping provides an efficient and precise approach to both genome-wide mapping and fine mapping of rice genes.HU GuangLong ZHANG DongLing PAN HuiQiao LI Ben WU JianTao ZHOU XueYa ZHANG QunYuan ZHOU Lei YAO GuoXin LI JunZhou LI JinJie ZHANG HongLiang LI ZiChao 2011Chinese Science Bulletin2011,56,9:4
19Shp-2/NF-κB Pathway Mediates the Inhibition of Lipoxin A4 onIL-1β-induced Synthesis of IL-6 in Glomerular Mesangial Cells显示文摘Objective: To examine whether lipoxin A4 (LXA4) has an antagonistic effect on IL-1β-induced synthesis of IL-6 in glomerular mesangial cells, and to explore the molecular mechanisms of signal pathway in LXA4 actions. Methods: The glomerular mesangial cells of rat were cultured and treated with IL-1β with or without preincubation with LXA4 at different concentrations. The amount of IL-6 in the supernatant of cells was analyzed by enzymelinked immunosorbent assay(ELISA). The expressions of mRNA of IL-6 were determined by RT-PCR. The expressions of Src homology 2( SH2 ) containing protein-tyrosine phosphatase 2(Shp-2) were assessed by immunoprecipitation and immunoblotting. Activities of DNA-binding of nuclear factor-kappa B(NF-κB) were measured by electrophoretic mobility shift assay(EMSA). Results:IL-1β- snulated secretion of protein and expression of mRNA of IL-6 in mesangial cells were inhibited by LXA4 in a dose-dependent manner. LXA4 antagonizes the phosphorylation of Shp-2 and activities of NF-κB induced by IL-1β Conclusion: LXA4 antagonists IL-1β-induced synthesis of IL-6 in glomerular mesangial cellsthrough the mechanism of Shp-2/NF-κB pathway-dependent signal transduction.WUSheng-hua LUChao DONGLing CHENZi-qing 2004Journal of Nanjing Medical University2004,18,4:4
20Bt protein expression in the transgenic insect-resistant cotton in China显示文摘According to statistics of International Service for the Acquisition of Agri-biotech Applications(ISAAA),18million farmers in 28 countries planted more than 181million hectares of genetically modified(GM)crops in2014,at an annual growth rate of between 3%–4%,with6.3 million ha more than 2013[1].Among these counties,China ranks the sixth with 3.9 million ha.Globally,27kinds of transgenic crops have been approved.The four main food groups for which GM varieties areGuoqing Sun Dongling Zhang Rui Zhang Yuan Wang Zhigang Meng Tao Zhou Chenzhen Liang Tao Zhu Sandui Guo 2016Science Bulletin2016,61,20:3
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