2篇
您的检索式：作者名="DING Shanting"
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| 1 | Extended depth of field through an axicon 显示文摘 | ZHAI Zhongsheng DING Shanting L1] Qinghua | 2009 | Journal of Modern Optics(S0950-0340)2009，6，11： | 1 |
| 2 | Influence of superior cervical ganglionectomy on hippocampal neurogenesis and learning and memory in adult rats显示文摘BACKGROUND:Studies have shown that neurogenesis in the dentate gyrus plays an important role in learning and memory.However,studies have not determined whether the superior cervical ganglion or the sympathetic nerve system influences hippocampal neurogenesis or learning and memory in adult rats. OBJECTIVE:To observe differences in dentate gyrus neurogenesis,as well as learning and memory,in adult rats following superior cervical ganglionectomy. DESIGN,TIME AND SETTING:A randomized,controlled,animal study was performed at the Immunohistochemistry Laboratory of the School of Life Sciences in Lanzhou University from July 2006 to July 2007. MATERIALS:Doublecortin polyclonal antibody was provided by Santa Cruz Biotechnology,USA; avidin-biotin-peroxidase complex was purchased from Zhongshan Goldenbride Biotechnology, China;Morris water maze was bought from Taimeng Technology,China. METHODS:A total of 20 adult,male,Wistar rats were randomly divided into surgery and control groups,with 10 rats in each group.In the surgery group,the bilateral superior cervical ganglions were transected.In the control group,the superior cervical ganglions were only exposed,but no ganglionectomy was performed. MAIN OUTCOME MEASURES:To examine distribution,morphology,and number of newborn neurons in the dentate gyrus using doublecortin immunohistochemistry at 36 days following surgical procedures.To examine ability of learning and memory in adult rats using the Morris water maze at 30 days following surgical procedures. RESULTS:Doublecortin immunohistochemical results showed that a reduction in the number of doublecortin-positive neurons in the surgery group compared to the control group(P<0.05),while the distribution of doublecortin-positive neurons was identical in the two groups.The surgery group exhibited significantly worse performance in learning and spatial memory tasks compared to the control group(P<0.05). CONCLUSION:Superior cervical ganglionectomy inhibited neurogenesis in the dentate gyrus and decreased learning and memory abilities in adult rats. | Yanping Ding Baoping Shao Shiyuan Yu Shanting Zhao Jianlin Wang | 2009 | Neural Regeneration Research2009，4，9： | 1 |
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