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| 1 | 应用ImageJ程序包进行材料显微组织图像处理、分析和可视化的一种框架(英文)显示文摘显微组织图像(例如胞、粒子与晶粒等)的数字图像处理、分割和分析,对于获取显微组织特征的三维信息非常重要。已有数种商用和共享程序包可以用于图像的处理和分析。'ImageJ'即其中之一,其长期广泛采用及其可扩展插件形式已使其成为许多不同应用领域科学家选用的工具。它包含了处理、分割、重建和可视化材料显微结构所需要的几乎所有基本的和最新的功能以及图像分析工具(例如‘Particle Analyzer’,‘3D object counter’,‘3D Roi Manager’),以用于成组粒子的复杂统计处理。虽然它在生物医学研究领域很受欢迎,被认为是一种有用的和有效的开放源码的图像处理与分析软件,但是在材料科学领域对其所知甚少。面向材料学界,本文尤其是那些没有图像处理和分析经验的材料科学与工程专业人员,在简要介绍ImageJ的基础上,提出了将其应用于在三维空间中处理、分割和分析显微组织结构连续切片图像的一个通用框架。 | Asad Ullah 刘国权 王浩 Dil Faraz Khan Matiullah Khan | 2012 | 中国体视学与图像分析2012，17，4： | 7 |
| 2 | Improvement of a High Velocity Compaction Technique for Iron Powder显示文摘Water atomized pure iron powder was compacted by high velocity compaction(HVC) with and without upper relaxation assist(URA) device.The influence of URA device on green density,spring back,green strength and hardness was studied.Morphological characteristics of the samples were observed by scanning electron microscope(SEM).Green strength of the samples was measured by computer controlled universal testing machine.The results show that as stroke length increases,the green density,green strength and hardness of the compacts increase gradually.At the identical stroke length,the green density of the compacts pressed with URA devise was 2% higher than the compacts pressed without URA device.The green strength and hardness of the compacts pressed with URA device were higher than the compacts pressed without URA device.Furthermore,the radial spring back of the compacts decreased gradually with the increment in stroke length,whilst that of compacts prepared with URA device was lower. | Dil Faraz KHAN Haiqing YIN Zahid USMAN Matiullah KHAN Xianjie YUAN Wenhao WANG Xuanhui QU | 2013 | Acta Metallurgica Sinica(English Letters)2013，26，4： | 4 |
| 3 | Phase microstructure evaluation and microwave dielectric properties of (1-x)Mg_(0.95)Ni_(0.05)Ti_(0.98)Zr_(0.02)O_3–xCa_(0.6)La_(0.8/3)TiO_3 ceramics显示文摘All the compositions in the(1-x)Mg_(0.95)Ni_(0.05)Ti_(0.98)Zr_(0.02)O_3–xCa_(0.6)La_(0.8/3)TiO_3(0 ≤ x ≤ 0.2) series were fabricated using solid state sintering route. Mg_(0.95)Ni_(0.05)Ti_(0.98)Zr_(0.02)O_3 possessed excellent microwave dielectric properties with ε_r ≈ 17.1, Q_uf_0 ≈ 195855 GHz, and τ_f ≈-46 ppm/℃. t f was tuned through zero by mixing with Ca_(0.6)La_(0.8/3)TiO_3. In the present study, τ_f ≈-2 ppm/℃ with er ≈ 23.9 and high Q_uf_0 ≈ 115870 GHz was achieved for x = 0.15, i.e., for a mixture of 85% Mg_(0.95)Ni_(0.05)Ti_(0.98)Zr_(0.02)O_3–xCa_(0.6)La_(0.8/3)TiO_3. | Abdul MANAN Zahid ULLAH Arbab Safeer AHMAD Atta ULLAH Dil Faraz KHAN Arshad HUSSAIN Mati Ullah KHAN | 2018 | Journal of Advanced Ceramics2018，7，1： | 4 |
| 4 | Development of a panel of unigene-derived polymorphic EST–SSR markers in lentil using public database information显示文摘Lentil(Lens culinaris Medik.), a diploid(2n = 14) with a genome size greater than 4000 Mbp, is an important cool season food legume grown worldwide. The availability of genomic resources is limited in this crop species. The objective of this study was to develop polymorphic markers in lentil using publicly available curated expressed sequence tag information(ESTs). In this study, 9513 ESTs were downloaded from the National Center for Biotechnology Information(NCBI) database to develop unigene-based simple sequence repeat(SSR) markers. The ESTs were assembled into 4053 unigenes and then analyzed to identify 374 SSRs using the MISA microsatellite identification tool. Among the 374 SSRs, 26 compound SSRs were observed.Primer pairs for these SSRs were designed using Primer3 version 1.14. To classify the functional annotation of ESTs and EST–SSRs, BLASTx searches(using E-value 1 × 10-5) against the public UniP rot(http://gffzzc0d2db89b939488bhonx6uv9bvfbu6599.ffgz.tsg.suse.edu.cn/) and NCBI(http://gffzz5b533c64939a43b3honx6uv9bvfbu6599.ffgz.tsg.suse.edu.cn/) databases were performed. Further functional annotation was performed using PLAZA(version3.0) comparative genomics and GO annotation was summarized using the Plant GO slim category. Among the synthesized 312 primers, 219 successfully amplified Lens DNA. A diverse panel of 24 Lens genotypes was used to identify polymorphic markers. A polymorphic set of 57 markers successfully discriminated the test genotypes. This set of polymorphic markers with functional annotation data could be used as molecular tools in lentil breeding. | Debjyoti Sen Gupta Peng Cheng Gaurav Sablok Dil Thavarajah Pushparajah Thavarajah Clarice J.Coyne Shiv Kumar Michael Baum Rebecca J.McGee | 2016 | The Crop Journal2016，4，5： | 2 |
| 5 | An Investigation of Landslide Susceptibility Using Logistic Regression and Statistical Index Methods in Dailekh District, Nepal显示文摘Landslide distribution and susceptibility mapping are the fundamental steps for landslide-related hazard and disaster risk management activities, especially in the Himalaya region which has resulted in a great deal of death and damage to property. To better understand the landslide condition in the Nepal Himalaya, we carried out an investigation on the landslide distribution and susceptibility using the landslide inventory data and 12 different contributing factors in the Dailekh district, Western Nepal. Based on the evaluation of the frequency distribution of the landslide, the relationship between the landslide and the various contributing factors was determined.Then, the landslide susceptibility was calculated using logistic regression and statistical index methods along with different topographic(slope, aspect, relative relief, plan curvature, altitude, topographic wetness index) and non-topographic factors(distance from river, normalized difference vegetation index(NDVI), distance from road, precipitation, land use and land cover, and geology), and 470(70%) of total 658 landslides. The receiver operating characteristic(ROC) curve analysis using 198(30%) of total landslides showed that the prediction curve rates(area under the curve, AUC) values for two methods(logistic regression and statistical index) were 0.826, and 0.823with success rates of 0.793, and 0.811, respectively. The values of R-Index for the logistic regression and statistical index methods were83.66 and 88.54, respectively, consisting of high susceptible hazard classes. In general, this research concluded that the cohesive and coherent natural interplay of topographic and non-topographic factors strongly affects landslide occurrence, distribution, and susceptibility condition in the Nepal Himalaya region. Furthermore, the reliability of these two methods is verified for landslide susceptibility mapping in Nepal’s central mountain region. | DIL Kumar RAI XIONG Donghong ZHAO Wei ZHAO Dongmei ZHANG Baojun NIRMAL Mani DAHAL WU Yanhong MUHAMMAD Aslam BAIG | 2022 | Chinese Geographical Science2022，32，5： | 2 |
| 6 | Evaluation of biomarkers, genetic mutations, and epigenetic modifications in early diagnosis of pancreatic cancer显示文摘BACKGROUND Pancreatic cancer(PC)is one of the deadliest malignancies with an alarming mortality rate.Despite significant advancement in diagnostics and therapeutics,early diagnosis remains elusive causing poor prognosis,marred by mutations and epigenetic modifications in key genes which contribute to disease progression.AIM To evaluate the various biological tumor markers collectively for early diagnosis which could act as prognostic biomarkers and helps in future therapeutics of PC in Kashmir valley.METHODS A total of 50 confirmed PC cases were included in the study to evaluate the levels of carbohydrate antigen 19-9(CA 19-9),tissue polypeptide specific antigen(TPS),carcinoembryonic antigen(CEA),vascular endothelial growth factor-A(VEGF-A),and epidermal growth factor receptor(EGFR).Mutational analysis was performed to evaluate the mutations in Kirsten rat sarcoma(KRAS),Breast cancer type 2(BRCA-2),and deleted in pancreatic cancer-4(DPC-4)genes.However,epigenetic modifications(methylation of CpG islands)were performed in the promoter regions of cyclin-dependent kinase inhibitor 2A(p16;CDKN2A),MutL homolog 1(hMLH1),and Ras association domain-containing protein 1(RASSF1A)genes.RESULTS We found significantly elevated levels of biological markers CA 19-9(P≤0.05),TPS(P≤0.05),CEA(P≤0.001),and VEGF(P≤0.001).Molecular genetic analysis revealed that KRAS gene mutation is predominant in codon 12(16 subjects,P≤0.05),and 13(12 subjects,P≤0.05).However,we did not find a mutation in DPC-4(1203G>T)and BRCA-2(617delT)genes.Furthermore,epigenetic modification revealed that CpG methylation in 21(P≤0.05)and 4 subjects in the promoter regions of the p16 and hMLH1 gene,respectively.CONCLUSION In conclusion,CA 19-9,TPS,CEA,and VEGF levels were significantly elevated and collectively have potential as diagnostic and prognostic markers in PC.Global data of mutation in the KRAS gene commonly in codon 12 and rare in codon 13 could augment the predisposition towards PC.Additionally,methylation of the p16 gene could also modulate transcription of genes thereby increasing the predisposition and susceptibility towards PC. | Bilal Rah Manzoor Ahmad Banday Gh Rasool Bhat Omar J Shah Humira Jeelani Fizalah Kawoosa Tahira Yousuf Dil Afroze | 2021 | World Journal of Gastroenterology2021，27，36： | 2 |
| 7 | 3D与2D腹腔镜胃旁路手术的手术时间与术者主观评价比较显示文摘背景与目的:肥胖发病率正在以'令人担忧'的速度快速增长,已成为严重威胁人类健康的重大问题。腹腔镜胃旁路手术是最常见的减肥手术之一。随着技术与设备的发展,3D腹腔镜成像系统逐步踏入普外科手术领域,三维立体图像弥补了传统2D腹腔镜成像系统缺乏纵深感、立体解剖描述不足的劣势,为主刀医师提供更加清晰的手术视野,使手术变得更加精细,一定程度上降低了难度。3D腹腔镜作为腹腔镜技术的重大革新,在胃旁路手术方面的应用却鲜有报道,与2D腹腔镜比较的优劣情况尚不明了。本研究通过单中心随机对照研究,探讨3D腹腔镜在胃旁路手术中的优势及应用价值。方法:选择中国医科大学附属第四医院2017年8月—2019年3月减重患者60例,随机分为两组,每组各30例,分别行2D腹腔镜胃旁路手术(2D组)与3D腹腔镜胃旁路手术(3D组)。比较两组完成各手术步骤(建立胃小囊、胃肠吻合及肠肠吻合)的用时及总体用时,采用调查问卷方式就术者对两组手术的镜下可操作性及舒适度行主观问卷评分。结果:两组患者术前一般资料无统计学差异(均P>0.05)。与2D组比较,3D组除胃小囊建立时间上无统计学差异外(P=0.120),胃肠吻合时间(P=0.015)、肠肠吻合时间(P=0.012)及手术总用时(P=0.023)均明显缩短。术者对3D腹腔镜下的精准性、层面感、纵深感主观评分以及眼部疲乏感、颈部疲乏感的主观评分均明显优于2D腹腔镜(均P<0.05)。结论:与2D腹腔镜比较,3D腹腔镜可显著缩短胃旁路手术的手术用时,有效的提高了术者操作的舒适度,具有良好的应用前景。 | Thapa Dil Momin 王墨飞 周勇 王勇 刘金钢 | 2020 | 中国普通外科杂志2020，29，6： | 2 |
| 8 | Correl atation (TID) male patient ion and 显示文摘 | Aldhilan between coronary A Syed GM transient i Suleiman I schemic dil artery disease in Saudi | 2014 | J Saudi Heart hssoc2014，26，1： | 1 |
| 9 | Chitosan coatings with distinct innate immune bioactivities differentially stimulate angiogenesis,osteogenesis and chondrogenesis in poly-caprolactone scaffolds with controlled interconnecting pore size显示文摘This study tested whether osseous integration into poly(ε-caprolactone)(PCL)bioplastic scaffolds with fully-interconnecting 155±8μm pores is enhanced by an adhesive,non-inflammatory 99% degree of deacetylation(DDA)chitosan coating(99-PCL),or further incorporation of pro-inflammatory 83% DDA chitosan microparticles(83-99-PCL)to accelerate angiogenesis.New Zealand White rabbit osteochondral knee defects were press-fit with PCL,99-PCL,83-99-PCL,or allowed to bleed(drill-only).Between day 1 and 6 weeks of repair,drill-only defects repaired by endochondral ossification,with an 8-fold higher bone volume fraction(BVF)versus initial defects,compared to a 2-fold(99-PCL),1.1-fold(PCL),or 0.4-fold(83-99-PCL)change in BVF.Hematoma innate immune cells swarmed to 83-99-PCL,elicited angiogenesis throughout the pores and induced slight bone resorption.PCL and 99-PCL pores were variably filled with cartilage or avascular mesenchyme near the bone plate,or angiogenic mesenchyme into which repairing trabecular bone infiltrated up to 1 mm deep.More repair cartilage covered the 99-PCL scaffold(65%)than PCL(18%)or 83-99-PCL(0%)(p<0.005).We report the novel finding that non-inflammatory chitosan coatings promoted cartilage infiltration into and over a bioplastic scaffold,and were compatible with trabecular bone integration.This study also revealed that in vitro osteogenesis assays have limited ability to predict osseous integration into porous scaffolds,because(1)in vivo,woven bone integrates from the leading edge of regenerating trabecular bone and not from mesenchymal cells adhering to scaffold surfaces,and(2)bioactive coatings that attract inflammatory cells induce bone resorption. | Caroline D.Hoemann Javier Rodríguez Gonzalez Jessica Guzman-Morales Gaoping Chen Ebrahim Jalali Dil Basil D.Favis | 2022 | Bioactive Materials2022，7，4： | 1 |
| 10 | High-temperature optical fiber thermometer显示文摘 | Dils R R | 1983 | Appl Phys1983，54，3： | 1 |
| 11 | Prevalence of knee osteoarthritis in the United States:arthritis data from the National Health and Nutrition Examination Survey 1991-1994显示文摘 | Dil on CF Rasch EK Gu Q | | 0，，11： | 1 |
| 12 | Characterising phosphorus loss in surface and subsurface hydrological pathways显示文摘 | Heathwaite A L Dils R M | 2000 | Science of the Total Environment2000，25，1： | 1 |
| 13 | Evaluation of group counseling for women with breast cancer in Turkey显示文摘 | Oz F Dil S Inci F | 2012 | Cancer Nurs2012，35，4： | 1 |
| 14 | Clinical evaluation of glimepiride versus glyburide in NIDDM in a double-blind comparative study Glimepiride/Glyburide Research Group显示文摘 | Dil s DG Schneider J | | 0，，09： | 1 |
| 15 | High-temperature optical fiber thermometer显示文摘 | Dils R R | 1983 | Journal of Applied Physics1983，54，3： | 1 |
| 16 | Characterising phosphorus loss in surface and subsurface hydrological pathways显示文摘 | Heathwaite A L Dils R M | 2000 | Science of the Total Envi- ronment2000，251，： | 1 |
| 17 | High temperature optical fiber thermometer 显示文摘 | DILS R R | 1983 | Journal of Applied Physics1983，54，3： | 1 |
| 18 | Supplementary concentrate type af ects nitrogen excretion of grazing dairy cows显示文摘 | Mul igan F J Dil on P Cal an J J | | 0，，10： | 1 |
| 19 | Characterising phosphorous loss in surface and subsurface hydrological pathways显示文摘 | Heathwaite A L Dils R M | 2000 | Science of the Total Environment2000，25，1： | 1 |
| 20 | Evaluation of polymerase chain reaction for rapid diagnosis of clinically suspected tuberculous pleurisy显示文摘 | Dil Afroze Sharma D Dhobi GN | | 0，，02： | 1 |
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