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| 1 | MicroRNA sequences modulating inflammation and lipid accumulation in macrophage “foam” cells: Implications for atherosclerosis显示文摘Accumulation of macrophage'foam'cells,laden with cholesterol and cholesteryl ester,within the intima of large arteries,is a hallmark of early'fatty streak'lesions which can progress to complex,multicellular atheromatous plaques,involving lipoproteins from the bloodstream and cells of the innate and adaptive immune response.Sterol accumulation triggers induction of genes encoding proteins mediating the atheroprotective cholesterol efflux pathway.Within the arterial intima,however,this mechanism is overwhelmed,leading to distinct changes in macrophage phenotype and inflammatory status.Over the last decade marked gains have been made in understanding of the epigenetic landscape which influence macrophage function,and in particular the importance of small non-coding micro-RNA(miRNA)sequences in this context.This review identifies some of the miRNA sequences which play a key role in regulating'foam'cell formation and atherogenesis,highlighting sequences involved in cholesterol accumulation,those influencing inflammation in sterol-loaded cells,and novel sequences and pathways which may offer new strategies to influence macrophage function within atherosclerotic lesions. | Richard James Lightbody Janice Marie Walsh Taylor Yvonne Dempsie Annette Graham | 2020 | World Journal of Cardiology2020，12，7： | 7 |
| 2 | A case-control study of maternal recreational physical activity and risk of gestational diabetes mellitus 显示文摘 | Dempsy JC Butler CL Sorensen TK | 2004 | Diabetes Res Clin Pract2004，66，2： | 1 |
| 3 | A role for miR-145 in pulmonary arterial hypertension:evidence from mouse models and patient samples显示文摘 | Caruso P Dempsie Y Stevens HC | 2012 | Circ Res2012，111，3： | 1 |
| 4 | Interaction of sleep state and chemical stimuli in sustaining rhythmic ventilation显示文摘 | Skatrud J Dempsy J | 1983 | J Appl Physiol1983，55，： | 1 |
| 5 | A role for miR-145 in pulmonary arterial hypertension: evidence from mouse models and patient samples显示文摘 | Caruso P Dempsie Y Stevens HC | 2012 | Circ Res2012，111，3： | 1 |
| 6 | The serotonin hypothesis of pulmonary hypertension revisited显示文摘 | Maclean MR Dempsie Y | 2010 | Adv Exp Med Biol2010，661，： | 1 |
| 7 | Integration of cytokine biology and lipid metabolism in stroke 显示文摘 | Adibhatla R M Dempsy R Hatcher J F | 2008 | Front Biosci2008，83，13： | 1 |
| 8 | A role for miR-145 in pulmonary arterial hypertension : evidence from mouse models and patient samples显示文摘 | Caruso P Dempsie Y Stevens HC | 2012 | Circ Res2012，111，3： | 1 |
| 9 | Pulmonary hypertension: therapeutic tar-gets; within the serotonin system显示文摘 | Dempsie Y Maclean MR | 2008 | J Pharmacol2008，155，4： | 1 |
| 10 | Serotonin and pulmonary hypertensionfrombench to bedside? 显示文摘 | Maclean MR Dempsie Y | 2009 | Curr opin Pharmacol2009，9，3： | 1 |
| 11 | A case control study of maternal recreational physical activity and risk of gestational diabetes melitus显示文摘 | Dempsy JC Buffer CL Sorensen TK | 2004 | Diabetes Res Clin Pract2004，66，： | 1 |
| 12 | Endothelial apoptosis in pulmonary hypertension is controlled by a microRNA/programmed cell death 4/caspase-3axis显示文摘 | White K Dempsie Y Caruso P | 2014 | Hypertension2014，64，1： | 1 |
| 13 | Polyamine response to CNS injury:For better Or for worse显示文摘 | Rao AM Hatcher JF Dempsy RJ | 1999 | Recent Research Development in Neurochemistry1999，2，： | 1 |
| 14 | C3d of complement as molecular adjuvant:bridging innate and acquired immunity显示文摘 | Dempsy P W Allison M E Akkaraju S | 1996 | Science1996，271，： | 1 |
| 15 | The serotonin hypothesis of pulmonary hypertension revised显示文摘 | Maclean MR Dempsie Y | 2010 | Adv Exp Med Biol2010，661，： | 1 |
| 16 | Individualizing management of aggressive fibromatoses显示文摘 | Matthew A. Spear L.Candace Jennings Henry J. Mankin Ira J. Spiro Dempsy S. Springfield Mark C. Gebhardt Andrew E. Rosenberg James T. Efird Herman D. Suit | 1998 | International Journal of Radiation Oncology, Biology, Physics1998，，： | 1 |
| 17 | Integration of cy- tokinebio- logy and lipid metabolism in stroke 显示文摘 | Adibhatla RM Dempsy R Hateher JF | 2008 | Front Biosci2008，13，1： | 1 |
| 18 | A case control study of maternal recreational physical activity and risk of gestation diabetes melitus显示文摘 | Dempsy J C Butler C L Sorensern T K | 2004 | Diabetes Res Clin Praot2004，66，2： | 1 |
| 19 | A case controstuay of maternal recreational physical activity and risk ogestational diabetes mellitus显示文摘 | Dempsy JC Buffer CL Sorensen TK | | 0，，02： | 1 |
| 20 | Pulmonary hypertension:therapeutic targets within the serotonin system显示文摘 | Dempsie Y Mac Lean MR | 2008 | Br J Pharmacol2008，155，4： | 1 |
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