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	题名	作者	年代	出处	被引量
1	血浆游离DNA水平增高可作为预测重型颅脑损伤患者死亡率的独立指标(英文)显示文摘Trauma is the leading cause of death under 45 years worldwide and up to 50% of trauma fatalities are due to brain injury.Prediction of outcome is one of the major problems associated with severe TBI and research efforts have focused on the investigation of biomarkers with prognostic value following TBI. Therefore,our aim was to investigate whether cell-free DNA concentrations correlated to short-term primary outcome( survivor or death) and GCS scores following severe TBI. A total of 188 victims of severe TBI were enrolled in this prospective study,outcome variables comprised: survival and neurological assessment using the GCS at ICU discharge. Control blood samples were obtained from 25 healthy volunteers. Peripheral venous blood was collected at admission in the ICU. Plasma DNA was measured using a real-time quantitative PCR assay for the β-globin gene. There was correlation between higher DNA levels and both fatal outcome and lower hospital admission GCS scores. Plasma DNA concentrations at the chosen cut- off point( ≥171,381 kilogenomesequivalents /L) predicted mortality with a specificity of 90% and a sensitivity of 43%. Logistic regression analysis showed that elevated plasma DNA levels were independently associated with death( P < 0. 001). In conclusion,high cell-free DNA concentration was a predictor of short-term mortality following severe TBI.	Rodrigues Filho EM1 Simon D Ikuta N Klovan C Dannebrock F de Oliveira CO Regner A	2014	中华神经外科疾病研究杂志2014，13，3：	6
2	Insulin resistance in epileptic girls who gain weight after therapy with valproic acid显示文摘	Verrotti A Basciani F De Simone M	2002	J Child Neurol2002，17，4：	1
3	查看详情显示文摘	Mijatovic T De Nève N Bruyère C Simon G Dewelle J Van Quaquebeke E Van Der A.E Van Vynckt F Lefranc F Kiss R		0，，：	1
4	Two-phase n-butenes dimerization by nickel complexes in molten salt media显示文摘	Dupont J de Souza R F	1998	Appl Catal A:General1998，775，：	1
5	The effect of a levonorgestrel-releasing intrauterine device in the treatment of myoma-related menorrhagia显示文摘	Mercorio F De Simone R Di Zpiezio Sardo A	2003	Contraception2003，67，4：	1
6	Quantification of clinical morbidity associated with schistosome infection in sub-Saharan Africa显示文摘	Marieke J van der Werf Sake J de Vlas Simon Brooker Caspar W.N Looman Nico J.D Nagelkerke J.Dik F Habbema Dirk Engels	2003	Acta Tropica2003，，2：	1
7	Multiple right-sid-ed pulmonary nodules : metastatic cancer or resectable earlystage tumor? 显示文摘	Cioffi U Raveglia F De Simone M	2011	J Cardiothorac Surg2011，6，：	1
8	Fludarabine and cytarabine as continuous sequential infusion for elderly patients with acute myeloid leukemia显示文摘	Ferrara F D'Arco AM De Simone M	2005	Haematologica2005，90，6：	1
9	Three-dimensional Color Doppler Reconstruction of Intracardic Blood Flow in Patients with Different Heart Valve Disease显示文摘	DE SIMONE R GLOMBITZA G VAHL C F	2000	Am J Cardiol2000，86，：	1
10	Appraisal of the coordinator-based transplant organizational model显示文摘	FilipponiF De Simone P Mosca F	2005	Transplant Proc2005，37，6：	1
11	Renal function at two years in liver transplant patients receiving everolimus: results of a randomized, multicenter study 显示文摘	Saliba F De Simone P Nevens F	2013	Am J Transplant2013，13，7：	1
12	High-dose idarubicin and busulphan as conditioning to autologous stem cell transplan- tation in adult patients with acute myeloid leukaemia 显示文摘	Ferrara F Palmieri S De Simone M	2005	Br J Haematol2005，128，2：	1
13	Appraisal of the coordinator: based transplant organizational model 显示文摘	Filipponi F de Simone P Mosca F	2005	Transplant Proc2005，37，6：	1
14	Link of nonhemodynamic factors to hemodyoamic determinants of left ventricular hypertrophy 显示文摘	De Simone G Pesamsi F Contaldo F	2001	Hypertension2001，38，1：	1
15	Hypoglycemic effects of sesquiterpene glycosides and polyhydroxylated triterpenoids of Eriobotrya japonica显示文摘	de Tommasi N de Simone F Cirino G	1991	Planta Med1991，57，5：	1
16	Inhibitory Action of Aqueous Garlic Peel Extract on the Corrosion of Carbon Steel in HCl Solution显示文摘	SIMONE S de A A P MICHELLE M P TATIANA L F		0，，：	1
17	Minimally invasive oxygen- ozone therapy for lumbar disk hemation 显示文摘	Andreyla C F Simon etti L De Santis F	2003	AJNR Am J Neurordiol2003，24，5：	1
18	Indirect composite restorations in the anterior region: a predictable technique for complex cases显示文摘	Vanini L De Simone F Tammaro S	1997	Pract Periodontics Aesthet Dent1997，9，80：	1
19	Constituents of Eriobotrya japonica,a study of their antiviral properties显示文摘	de Tommasi N de Simone F Pizza C	1992	J Nat Prod1992，55，8：	1
20	Link of nonhemodynamic factors to hemodynamic determinants of left ventricular hypertrophy显示文摘	De Simone G Pasanisi F Contaldo F	2001	Hypertension2001，38，1：	1

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