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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Comparative study of the spectroscopic properties of Yb3+/Er3+ codoped tellurite glasses modified with R2O(R = Li,Na and K)显示文摘 | DESIRENA H De la ROSA E ROMERO V H | | 0，，02： | 1 |
| 3 | A key role of leptin in the control of regulatory T cell proliferation显示文摘 | De Rosa V Procaccini C Cali G | 2007 | Immunity2007，26，2： | 1 |
| 4 | A key role of leptin in the control of regulatory T cell proliferation显示文摘 | De Rosa V Procaecini C Call G | 2007 | Immunity2007，26，2： | 1 |
| 5 | 3D spiral computerized tomography in the reconstructive treatment of malignant maxillofacial tumors显示文摘 | De Rosa V Ionna F Mozzillo N | 2000 | Radiol Med(Torino)2000，100，6： | 1 |
| 6 | Diffusion-weigh- ted imaging findings in Perthes disease with dynamic gadolini- um-enhanced subtracted (DGS) MR correlation: a preliminary study 显示文摘 | Merlini L Combescure C De Rosa V | 2010 | Pediatr Radiol2010，40，3： | 1 |
| 7 | Identification,isolation,characterization,and banking of human dental pulp stem cells显示文摘 | Tirino V Paino F De Rosa A | | 0，，： | 1 |
| 8 | At the crossroad of T cells,adipose tissue,and diabetes显示文摘 | Matarese G Procaccini C De Rosa V | 2012 | Immunol Rev2012，249，1： | 1 |
| 9 | 3D spiral computerized to- mography in the reconstructive treatment of malignant maxillofa- cial tumors显示文摘 | De Rosa V Ionna F Mozzillo N | 2000 | Radiol Med2000，100，6： | 1 |
| 10 | Recognition and autocompletion of partially drawn symbols by using polar histograms as spatial relation descriptors显示文摘 | Costagliola G de Rosa M Fuccella V | 2014 | Computers & Graphics2014，39，2： | 1 |
| 11 | Epilepsy, occipital calcifications, and oligosymptomatic celiac disease in childhood显示文摘 | Arroyo HA De Rosa S Ruggieri V | 2002 | J Child Neurol2002，17，11： | 1 |
| 12 | Protective effect of selenium supplementation on the genotoxicity of di (2-ethyl- hexyl) phthalate and mono (2-ethylhexyl) phthalate treat- ment in LNCaP cells显示文摘 | Erkekolu P Raehidi W De Rosa V | 2010 | Free Radie Biol Med2010，49，4： | 1 |
| 13 | A key role of leptin in the control of regulatory T cell proliferation 显示文摘 | De Rosa V Procaccini C Call G | 2007 | Immunity2007，26，2： | 1 |
| 14 | Stable, inducible thermoacidophilic alpha-amylase from Bacillus acidocaldarius 显示文摘 | BUONOCORE V CAPORALE C DE ROSA M | 1976 | J Baeteriol1976，128，2： | 1 |
| 15 | Phase Ⅱ trial of temozolomide using protracted low-dose and whole-brain radiotherapy for non-small-cell lung cancer and breast cancer patients with brain metastases 显示文摘 | Addeo R De Rosa C Faiola V | 2008 | Cancer2008，113，9： | 1 |
| 16 | 3D piralcom P terized tomography in the re-constructive treatment of malignant maxillo-facial tumors显示文摘 | De Rosa V Ionna F Mozzillo N | 2000 | Radiol Med(Torino)2000，100，6： | 1 |
| 17 | On the double peak shape of melting endotherms of isothermally crystallized isotactic polypropylene samples 显示文摘 | PETRACg ONE V DE ROSA C GUERRA G | 1984 | Makromolekulare Chemie Rapid Commun1984，5，： | 1 |
| 18 | A key role of Leptin in the control of regulatory T cell proliferation 显示文摘 | De Rosa V Procaccini C Call G | 2007 | Immunity2007，26，2： | 1 |
| 19 | Intracellular metabolic pathways control immune tolerance 显示文摘 | PROCACCINI C GALGANI M DE ROSA V | 2012 | Trends Immu-nol2012，33，1： | 1 |
| 20 | Recognition and autocompletion of partially drawn symbols by using polar histograms as spatial relation descriptors显示文摘 | COSTAGLIOLA G DE ROSA M FUCCELLA V | 2014 | Computers & Graphics2014，39，4： | 1 |
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