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| 1 | Association of Helicobacter pylori infection and giardiasis: Results from a study of surrogate markers for fecal exposure among children显示文摘AIM: To investigate whether Helicobacter pylori (H pykori)infection is associated with hepatitis A virus (HAV) infection, presence of enteroparasites, and other surrogates of fecal exposure.METHODS: We conducted a cross-sectional study in 121 children consecutively admitted at a pediatric hospital inSalvador, Brazil.H pylori and HAV infection were identified by the presence of serum antibodies. Stool specimens were examined for the presence of ova and parasites. A structured questionnaire inquiring about sanitary conditions and life style was applied to each subject. RESULTS: Fifty-one of the 121 children (42.1%) werefound to be seropositive for H pylori, and 45 (37.2%) for HAV. The seroprevalence ofHpyloriand HAV both increased significantly with age. Cross-tabulation of data showed that 26 (21.5%) were seropositive and 51 (42.1%) were negative for bothHpyloriand HAV antibodies (χ2 = 7.18,OR = 2.8, CI 1.30-5.97). The age adjusted OR for an HAV-infected child being H pylori positive was 2.3 (CI1.02-5.03). The agreement between H pylori and HAVseropositivity was fair (κ = 0.24). After controlling for possible confounding, the variables remaining independently associated with seropositivity to H pyloriwere age,presence of Giardia lamblia in feces (OR = 3.2, 95%CI, 1.1-9.5) and poor garbage disposal quality (OR = 2.4,95%CI, 1.1-5.1).CONCLUSION: Our data suggest that H pylori infection is associated with surrogate markers of fecal exposure. Thus, we conclude that the fecal-oral route is relevant in the transmission of HP among children in an urban setting of a developing country. The association observed between G. lamblia and H pylori infection may have several explanations. Further studies to investigate this relationship are warranted. | Edson Duarte Moreira Jr Victor Bastos Nassri Rafaela Sousa Santos Junísia Ferraz Matos Wilson Andrade de Carvalho Célia Stolve Silvani Círia Santana e Sant'Ana | 2005 | World Journal of Gastroenterology2005，11，18： | 3 |
| 2 | Antiherpetic activity of a sulfated polysaccharide from Agaricus brasiliensis mycelia显示文摘 | Francielle Tramontini Gomes de Sousa Cardozo Carla Maísa Camelini Alessandra Mascarello Márcio José Rossi Ricardo José Nunes Célia Regina Monte Barardi Margarida Matos de Mendon?a Cláudia Maria Oliveira Sim?es | 2011 | Antiviral Research2011，，1： | 2 |
| 3 | S-adenosylmethionine in alcoholic liver cirrhosis: a randomized, placebo-controlled, double-blind, multicenter clinical trial显示文摘 | Mato JM Cámara J Fernández de Paz J | 1999 | J Hepatol1999，30，6： | 1 |
| 4 | Simultaneous follow-up of mouse colon lesions by colonoscopy and endoluminal ultrasound biomicroscopy显示文摘AIM:To evaluate the potential use of colonoscopy and endoluminal ultrasonic biomicroscopy(eUBM)to track the progression of mouse colonic lesions.METHODS:Ten mice were treated with a single azoxy-methane intraperitoneal injection(week 1)followed by seven days of a dextran sulfate sodium treatment in their drinking water(week 2)to induce inflammationassociated colon tumors.eUBM was performed simultaneously with colonoscopy at weeks 13,17-20 and21.A 3.6-F diameter 40 MHz mini-probe catheter was used for eUBM imaging.The ultrasound mini-probe catheter was inserted into the accessory channel of a pediatric flexible bronchofiberscope,allowing simultaneous acquisition of colonoscopic and eUBM images.During image acquisition,the mice were anesthetized with isoflurane and kept in a supine position over a stainless steel heated surgical waterbed at 37℃.Both eUBM and colonoscopic images were captured and stored when a lesion was detected by colonoscopy or when the eUBM image revealed a modified colon wall anatomy.During the procedure,the colon was irrigated with water that was injected through a flush port on the mini-probe catheter and that acted as the ultrasound coupling medium between the transducer and the colon wall.Once the acquisition of the last eUBM/colonoscopy section for each animal was completed,the colons were fixed,paraffin-embedded,and stained with hematoxylin and eosin.Colon images acquired at the first time-point for each mouse were compared with subsequent eUBM/colonoscopic images of the same sites obtained in the following acquisitions to evaluate lesion progression.RESULTS:All 10 mice had eUBM and colonoscopic images acquired at week 13(the first time-point).Two animals died immediately after the first imaging acquisition and,consequently,only 8 mice were subjected to the second eUBM/colonoscopy imaging acquisition(at the second time-point).Due to the advanced stage of colonic tumorigenesis,5 animals died after the second time-point image acquisition,and thus,only three were subjected to the third eUBM/colonoscopy imaging acquisition(the third time-point).eUBM was able to detect the four layers in healthy segments of colon:the mucosa(the first hyperechoic layer moving away from the mini-probe axis),followed by the muscularis mucosae(hypoechoic),the submucosa(the second hyperechoic layer)and the muscularis externa(the second hypoechoic layer).Hypoechoic regions between the mucosa and the muscularis externa layers represented lymphoid infiltrates,as confirmed by the corresponding histological images.Pedunculated tumors were represented by hyperechoic masses in the mucosa layer.Among the lesions that decreased in size between the first and third time-points,one of the lesions changed from a mucosal hyperplasia with ulceration at the top to a mucosal hyperplasia with lymphoid infiltrate and,finally,to small signs of mucosal hyperplasia and lymphoid infiltrate.In this case,while lesion regression and modification were observable in the eUBM images,colonoscopy was only able to detect the lesion at the first and second time-points,without the capacity to demonstrate the presence of lymphoid infiltrate.Regarding the lesions that increased in size,one of them started as a small elevation in the mucosa layer and progressed to a pedunculated tumor.In this case,while eUBM imaging revealed the lesion at the first time-point,colonoscopy was only able to detect it at the second time-point.All colonic lesions(tumors,lymphoid infiltrate and mucosal thickening)were identified by eUBM,while colonoscopy identified just76%of them.Colonoscopy identified all of the colonic tumors but failed to diagnose lymphoid infiltrates and increased mucosal thickness and failed to differentiate lymphoid infiltrates from small adenomas.During the observation period,most of the lesions(approximately67%)increased in size,approximately 14%remained unchanged,and 19%regressed.CONCLUSION:Combining eUBM with colonoscopy improves the diagnosis and the follow-up of mouse colonic lesions,adding transmural assessment of the bowel wall. | Rossana C Soletti Kelly Z Alves Marcelo AP de Britto Dyanna G de Matos Mnica Soldan Helena L Borges Joo C Machado | 2013 | World Journal of Gastroenterology2013，19，44： | 1 |
| 5 | Stimulation of Glutathione Synthesis of in Vitro Matured Bovine Oocytes and its Effect on Embryo Development and Freezability 显示文摘 | de Matos D G Furnus C C Moses D F | 1996 | M ol Reprod Dev1996，45，： | 1 |
| 6 | Copropagating and counterpropagating pumps in second-order-pumped discrete fiber Raman amplifiers显示文摘 | Chestnut D A de Matos C J S Reeves-Hall P C | 2002 | Optics Letters2002，27，19： | 1 |
| 7 | Effect of Cysteamine on Glutathione Level and Developmental Capacity of Bovine Oocyte Matured in Vitro显示文摘 | de Matos D G Furnus C C Moses D F | 1995 | Mol Reprod Dev1995，42，： | 1 |
| 8 | The hyaluronic acid receptor (CD44) is expressed in bovine oocytes and preimplantational stage embryos显示文摘 | Valcarcel A de Matos D G Furnus C C | 1999 | Theriogenology1999，51，： | 1 |
| 9 | All-fiber format compression of frequency chirped pulses in air-guiding photonic crystal fibers显示文摘 | de MATOS C J S POPOV S V | 2004 | Phys Rev Lett2004，93，10： | 1 |
| 10 | Exercise training restores baroreflex sensitivity in never-treated hypertensive patients显示文摘 | LATERZA M C DE MATOS L D TROMBETTA I C | 2007 | Hypertension2007，49，6： | 1 |
| 11 | Consumer reaction to service failure and recovery: the moderat- ing role of attitude toward complaining 显示文摘 | Augusto de Matos C Vargas Rossi C A Teixeira Veiga R | 2009 | Journal of Services Marketing2009，23，7： | 1 |
| 12 | Effect of hyaluronic acid on development of in vitro produced bovine enabryos 显示文摘 | FURNUS C C DE MATOS D G MARTINEZ A G | 1998 | Thefiogenology1998，49，： | 1 |
| 13 | Effect of hyaluronic acid on development of in vitro produced bovine embryos显示文摘 | Furnus C C de Matos D G Martinez A G | 1998 | Theriogenology1998，49，： | 1 |
| 14 | Effect oftheophylline on induced sputum inflammatory indices andneutrophil chemotaxis in chronic obstructive pulmonary dis-ease显示文摘 | CULPITT SV DE MATOS C RUSSELL RE | 2002 | Am J Respir Crit Care Med2002，，165： | 1 |
| 15 | Association of African swine fever virus withthe cytoskeleton显示文摘 | CARVALHO Z G DE MATOS A P A RODRIGUES-POUSADA C | 1988 | Virus Res1988，11，2： | 1 |
| 16 | Reli- able teleportation in trappedions显示文摘 | Solano E Cesar C L de Matos Filho R L | 2001 | European Physi- cal Journal D2001，13，1： | 1 |
| 17 | A Signal Peptide Derived from HSP60 Binds HLA-E and Interferes with CD94/ NKG2A Recognition 显示文摘 | Michaelsson J Teixeira de Matos C Achour A | 2002 | J Exp Med2002，，： | 1 |
| 18 | Fiber Bragg Grating(FBG) Characterization and Shaping by Local Pressure 显示文摘 | Matos de C J S Torres P Margulis W | 2001 | Lightwave Technology2001，19，8： | 1 |
| 19 | Effect of theophlline On induced sputum inflammatory jndices and neutmphil chemutaxis in chronic obstractive pulmonary disease显示文摘 | Culpittv V De Matos C Russ E I | 2006 | Am J Respir Crit Care2006，165，10： | 1 |
| 20 | Release and activity of matrixmetalloproteinase-9 and tissue inhibitor of metalloproteinase-lby alveolar maerophages from patients with chronic obstructive pulmonary disease 显示文摘 | Russell R E Culpitt S V De Matos C | 2002 | Am J Respir Cell Mol Biol2002，26，5： | 1 |
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